ko pathway ratio_in_study ratio_in_pop p_value ko05410 Hypertrophic cardiomyopathy (HCM) 22/205 100/7206 3.33198649287e-14 ko04260 Cardiac muscle contraction 21/205 98/7206 2.29838934642e-13 ko05414 Dilated cardiomyopathy 21/205 112/7206 3.64762365395e-12 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 14/205 79/7206 3.55908768693e-08 ko04512 ECM-receptor interaction 14/205 79/7206 3.55908768693e-08 ko04510 Focal adhesion 24/205 240/7206 6.33773605631e-08 ko04261 Adrenergic signaling in cardiomyocytes 22/205 205/7206 6.62823178774e-08 ko04974 Protein digestion and absorption 14/205 96/7206 4.46726194295e-07 ko01200 Carbon metabolism 14/205 128/7206 1.45458401849e-05 ko04921 Oxytocin signaling pathway 18/205 209/7206 2.50058485127e-05 ko04020 Calcium signaling pathway 20/205 265/7206 5.95141211917e-05 ko00010 Glycolysis / Gluconeogenesis 9/205 74/7206 0.000227908439744 ko05416 Viral myocarditis 7/205 55/7206 0.000866669097311 ko04022 cGMP-PKG signaling pathway 15/205 216/7206 0.00121012587278 ko00030 Pentose phosphate pathway 5/205 32/7206 0.00191032810494 ko04151 PI3K-Akt signaling pathway 22/205 390/7206 0.00236553980558 ko00680 Methane metabolism 5/205 34/7206 0.00252086149272 ko00020 Citrate cycle (TCA cycle) 5/205 35/7206 0.00287414125315 ko04010 MAPK signaling pathway 18/205 321/7206 0.00525659790644 ko00710 Carbon fixation in photosynthetic organisms 4/205 27/7206 0.00667937710623 ko04964 Proximal tubule bicarbonate reclamation 4/205 29/7206 0.00864859231364 ko01230 Biosynthesis of amino acids 7/205 85/7206 0.010308412489 ko00350 Tyrosine metabolism 4/205 33/7206 0.0136434358652 ko05034 Alcoholism 1/205 238/7206 0.0153735434102 ko04371 Apelin signaling pathway 11/205 177/7206 0.0176434710079 ko00250 Alanine, aspartate and glutamate metabolism 4/205 38/7206 0.0220551044727 ko05230 Central carbon metabolism in cancer 6/205 81/7206 0.0273373667407 ko04922 Glucagon signaling pathway 8/205 128/7206 0.0291932754955 ko00051 Fructose and mannose metabolism 4/205 42/7206 0.0306473488282 ko00620 Pyruvate metabolism 4/205 46/7206 0.0409612463548 ko05167 Kaposi's sarcoma-associated herpesvirus infection 1/205 191/7206 0.0453786890933 ko04911 Insulin secretion 7/205 117/7206 0.0488205312766