ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	153/783	423/7206	1.0470248386e-46
ko04724	Glutamatergic synapse	76/783	152/7206	2.69531134447e-34
ko05033	Nicotine addiction	45/783	56/7206	6.13782852156e-34
ko04727	GABAergic synapse	55/783	110/7206	5.01333438026e-25
ko05032	Morphine addiction	55/783	110/7206	5.01333438026e-25
ko04728	Dopaminergic synapse	69/783	185/7206	7.49281437942e-22
ko04723	Retrograde endocannabinoid signaling	66/783	175/7206	3.01552794404e-21
ko04713	Circadian entrainment	56/783	136/7206	2.64746419834e-20
ko04725	Cholinergic synapse	59/783	160/7206	1.53932613621e-18
ko04024	cAMP signaling pathway	82/783	279/7206	3.08875410663e-18
ko04020	Calcium signaling pathway	74/783	265/7206	3.30317692026e-15
ko04911	Insulin secretion	45/783	117/7206	3.34569069606e-15
ko04721	Synaptic vesicle cycle	34/783	80/7206	2.81647183385e-13
ko04726	Serotonergic synapse	46/783	137/7206	5.65782595271e-13
ko04261	Adrenergic signaling in cardiomyocytes	59/783	205/7206	5.96550082889e-13
ko04742	Taste transduction	28/783	61/7206	3.7045816419e-12
ko05031	Amphetamine addiction	35/783	91/7206	4.21489183564e-12
ko04921	Oxytocin signaling pathway	58/783	209/7206	5.07208776943e-12
ko04720	Long-term potentiation	36/783	99/7206	1.43072104392e-11
ko05030	Cocaine addiction	27/783	73/7206	3.412982808e-09
ko04010	MAPK signaling pathway	68/783	321/7206	3.53202878358e-08
ko04925	Aldosterone synthesis and secretion	31/783	105/7206	1.1044081827e-07
ko04970	Salivary secretion	29/783	95/7206	1.27688055137e-07
ko04514	Cell adhesion molecules (CAMs)	34/783	130/7206	9.44787979445e-07
ko04072	Phospholipase D signaling pathway	45/783	197/7206	1.0421420578e-06
ko04972	Pancreatic secretion	30/783	111/7206	1.43898936314e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	23/783	74/7206	1.80937974706e-06
ko03040	Spliceosome	1/783	145/7206	2.13780473961e-06
ko04971	Gastric acid secretion	27/783	98/7206	3.22952259216e-06
ko04730	Long-term depression	23/783	78/7206	4.94825881692e-06
ko04022	cGMP-PKG signaling pathway	46/783	216/7206	6.01606937195e-06
ko05203	Viral carcinogenesis	10/783	277/7206	1.19213903743e-05
ko04360	Axon guidance	47/783	233/7206	2.25955124445e-05
ko04260	Cardiac muscle contraction	25/783	98/7206	4.34638395975e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/783	79/7206	7.05374278807e-05
ko05168	Herpes simplex infection	5/783	182/7206	8.526506541e-05
ko04060	Cytokine-cytokine receptor interaction	6/783	191/7206	0.000130970886621
ko05322	Systemic lupus erythematosus	4/783	151/7206	0.000287896485851
ko05414	Dilated cardiomyopathy	25/783	112/7206	0.000353544995179
ko04740	Olfactory transduction	20/783	80/7206	0.000354259328377
ko04915	Estrogen signaling pathway	28/783	131/7206	0.000519275355589
ko00240	Pyrimidine metabolism	2/783	110/7206	0.00054559091643
ko04540	Gap junction	27/783	128/7206	0.000770311378029
ko04120	Ubiquitin mediated proteolysis	4/783	138/7206	0.000811269176746
ko05164	Influenza A	6/783	167/7206	0.000948223832789
ko04110	Cell cycle	5/783	145/7206	0.00173777184203
ko04014	Ras signaling pathway	47/783	279/7206	0.00218759059571
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/783	14/7206	0.00224845234752
ko04141	Protein processing in endoplasmic reticulum	8/783	184/7206	0.00245387459173
ko04621	NOD-like receptor signaling pathway	6/783	157/7206	0.00253540231422
ko04964	Proximal tubule bicarbonate reclamation	9/783	29/7206	0.00270792850249
ko04610	Complement and coagulation cascades	1/783	79/7206	0.00281502835153
ko04070	Phosphatidylinositol signaling system	23/783	112/7206	0.00306579572575
ko04750	Inflammatory mediator regulation of TRP channels	24/783	122/7206	0.00317745262774
ko03013	RNA transport	7/783	166/7206	0.00338743637214
ko04924	Renin secretion	18/783	86/7206	0.00500058355565
ko04350	TGF-beta signaling pathway	3/783	103/7206	0.00590325288725
ko04745	Phototransduction - fly	10/783	38/7206	0.00601944378321
ko04930	Type II diabetes mellitus	13/783	54/7206	0.00624507382208
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/783	182/7206	0.00746486935276
ko05169	Epstein-Barr virus infection	11/783	206/7206	0.00848688244359
ko03008	Ribosome biogenesis in eukaryotes	2/783	79/7206	0.0103583535253
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/783	59/7206	0.0105143434712
ko05231	Choline metabolism in cancer	24/783	134/7206	0.0115282492573
ko04064	NF-kappa B signaling pathway	3/783	96/7206	0.0118852078464
ko00330	Arginine and proline metabolism	1/783	61/7206	0.012303502091
ko05410	Hypertrophic cardiomyopathy (HCM)	19/783	100/7206	0.0140517578344
ko05034	Alcoholism	38/783	238/7206	0.0143674110165
ko04630	Jak-STAT signaling pathway	6/783	132/7206	0.0156173620702
ko05162	Measles	5/783	120/7206	0.0166506566909
ko04976	Bile secretion	16/783	80/7206	0.0166931657023
ko04114	Oocyte meiosis	24/783	139/7206	0.0189438462348
ko04722	Neurotrophin signaling pathway	27/783	160/7206	0.0198359541384
ko00310	Lysine degradation	2/783	73/7206	0.0214318686094
ko04015	Rap1 signaling pathway	42/783	278/7206	0.0237465949794
ko05161	Hepatitis B	10/783	173/7206	0.0258892147465
ko04371	Apelin signaling pathway	29/783	177/7206	0.0266273694771
ko00480	Glutathione metabolism	1/783	55/7206	0.0268946549897
ko04912	GnRH signaling pathway	21/783	122/7206	0.027804892748
ko04916	Melanogenesis	24/783	142/7206	0.0280535612403
ko03320	PPAR signaling pathway	2/783	69/7206	0.0303857734187
ko03018	RNA degradation	3/783	84/7206	0.0319807603903
ko04918	Thyroid hormone synthesis	16/783	86/7206	0.0337907763243
ko05016	Huntington's disease	14/783	215/7206	0.0344916977142
ko04270	Vascular smooth muscle contraction	25/783	154/7206	0.0359187752113
ko05205	Proteoglycans in cancer	19/783	271/7206	0.0364541222273
ko00380	Tryptophan metabolism	1/783	50/7206	0.0386803387964
ko04973	Carbohydrate digestion and absorption	9/783	42/7206	0.0414075331347
ko04012	ErbB signaling pathway	19/783	109/7206	0.0415670737778
ko04640	Hematopoietic cell lineage	2/783	64/7206	0.0426048623567
ko04550	Signaling pathways regulating pluripotency of stem cells	10/783	165/7206	0.042746375533
ko04142	Lysosome	9/783	151/7206	0.0476195690487