ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	140/694	423/7206	6.89646171547e-44
ko04724	Glutamatergic synapse	62/694	152/7206	5.63196334573e-25
ko05033	Nicotine addiction	37/694	56/7206	7.37634352938e-25
ko04721	Synaptic vesicle cycle	41/694	80/7206	1.979080284e-21
ko04728	Dopaminergic synapse	61/694	185/7206	5.24713806795e-19
ko04713	Circadian entrainment	50/694	136/7206	5.04943644292e-18
ko05032	Morphine addiction	43/694	110/7206	8.29783945097e-17
ko04727	GABAergic synapse	41/694	110/7206	3.16218092636e-15
ko04723	Retrograde endocannabinoid signaling	52/694	175/7206	3.05870626859e-14
ko04024	cAMP signaling pathway	66/694	279/7206	1.93707514348e-12
ko04725	Cholinergic synapse	46/694	160/7206	3.64174187765e-12
ko04911	Insulin secretion	38/694	117/7206	4.89424059049e-12
ko04921	Oxytocin signaling pathway	54/694	209/7206	5.05914665933e-12
ko05031	Amphetamine addiction	32/694	91/7206	2.27212019423e-11
ko04726	Serotonergic synapse	40/694	137/7206	5.74849403423e-11
ko04742	Taste transduction	25/694	61/7206	7.89711113041e-11
ko04261	Adrenergic signaling in cardiomyocytes	51/694	205/7206	9.17712986478e-11
ko04020	Calcium signaling pathway	60/694	265/7206	1.63649273691e-10
ko04970	Salivary secretion	29/694	95/7206	8.59988535158e-09
ko04966	Collecting duct acid secretion	14/694	26/7206	1.674063225e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	24/694	74/7206	4.557463746e-08
ko05030	Cocaine addiction	23/694	73/7206	1.58841429159e-07
ko04720	Long-term potentiation	26/694	99/7206	1.35066910138e-06
ko05203	Viral carcinogenesis	7/694	277/7206	3.67323241884e-06
ko05110	Vibrio cholerae infection	19/694	63/7206	3.97776465851e-06
ko04010	MAPK signaling pathway	56/694	321/7206	1.00272787442e-05
ko03040	Spliceosome	1/694	145/7206	1.13199704414e-05
ko05164	Influenza A	2/694	167/7206	1.34123805394e-05
ko04120	Ubiquitin mediated proteolysis	1/694	138/7206	2.60949253222e-05
ko04514	Cell adhesion molecules (CAMs)	28/694	130/7206	3.44552507068e-05
ko04971	Gastric acid secretion	23/694	98/7206	3.99187427935e-05
ko04060	Cytokine-cytokine receptor interaction	4/694	191/7206	5.24984239742e-05
ko05322	Systemic lupus erythematosus	2/694	151/7206	6.33546513882e-05
ko04022	cGMP-PKG signaling pathway	39/694	216/7206	9.17794355746e-05
ko05168	Herpes simplex infection	4/694	182/7206	0.000106805526753
ko04360	Axon guidance	41/694	233/7206	0.000108085750393
ko04924	Renin secretion	20/694	86/7206	0.000143830159209
ko04510	Focal adhesion	8/694	240/7206	0.000310143501626
ko04730	Long-term depression	18/694	78/7206	0.000338470735567
ko04260	Cardiac muscle contraction	21/694	98/7206	0.000380113499005
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/694	79/7206	0.000399849680458
ko05120	Epithelial cell signaling in Helicobacter pylori infection	20/694	92/7206	0.000461588481747
ko05205	Proteoglycans in cancer	11/694	271/7206	0.000713227986018
ko05162	Measles	2/694	120/7206	0.00085281888204
ko04621	NOD-like receptor signaling pathway	4/694	157/7206	0.000872957469976
ko04925	Aldosterone synthesis and secretion	21/694	105/7206	0.00115532729484
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/694	14/7206	0.00119150516024
ko04540	Gap junction	24/694	128/7206	0.00125545498155
ko04630	Jak-STAT signaling pathway	3/694	132/7206	0.00151780424007
ko04014	Ras signaling pathway	43/694	279/7206	0.00175705757159
ko00240	Pyrimidine metabolism	2/694	110/7206	0.00177533044271
ko05323	Rheumatoid arthritis	18/694	89/7206	0.00187477117733
ko03013	RNA transport	5/694	166/7206	0.00190365645992
ko04932	Non-alcoholic fatty liver disease (NAFLD)	6/694	182/7206	0.00197461038134
ko04745	Phototransduction - fly	10/694	38/7206	0.00250369090679
ko05169	Epstein-Barr virus infection	8/694	206/7206	0.0025555240004
ko05220	Chronic myeloid leukemia	1/694	85/7206	0.00277307512191
ko04972	Pancreatic secretion	21/694	111/7206	0.00285625368027
ko05414	Dilated cardiomyopathy	21/694	112/7206	0.00299817229271
ko05161	Hepatitis B	6/694	173/7206	0.00367508006328
ko04145	Phagosome	27/694	162/7206	0.00426352625381
ko05016	Huntington's disease	9/694	215/7206	0.00447529328185
ko04550	Signaling pathways regulating pluripotency of stem cells	6/694	165/7206	0.00485062350512
ko04964	Proximal tubule bicarbonate reclamation	8/694	29/7206	0.00488102352779
ko04626	Plant-pathogen interaction	6/694	18/7206	0.00526657177613
ko05146	Amoebiasis	2/694	99/7206	0.00533027988436
ko04612	Antigen processing and presentation	1/694	77/7206	0.0059828068588
ko05166	HTLV-I infection	15/694	292/7206	0.00601883694445
ko04610	Complement and coagulation cascades	1/694	79/7206	0.00610847286674
ko03008	Ribosome biogenesis in eukaryotes	1/694	79/7206	0.00610847286674
ko04140	Autophagy - animal	6/694	164/7206	0.00676464674269
ko05215	Prostate cancer	3/694	111/7206	0.00860151890532
ko04015	Rap1 signaling pathway	40/694	278/7206	0.00918316168522
ko01524	Platinum drug resistance	1/694	76/7206	0.00925345750899
ko04146	Peroxisome	2/694	89/7206	0.0108270526653
ko05222	Small cell lung cancer	2/694	89/7206	0.0108270526653
ko04141	Protein processing in endoplasmic reticulum	8/694	184/7206	0.0108629181637
ko04740	Olfactory transduction	15/694	80/7206	0.0113339137894
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/694	59/7206	0.0118483749249
ko04214	Apoptosis - fly	1/694	72/7206	0.0136247638772
ko04611	Platelet activation	7/694	163/7206	0.0152828165054
ko04350	TGF-beta signaling pathway	3/694	103/7206	0.0169939988621
ko04064	NF-kappa B signaling pathway	3/694	96/7206	0.0232016167213
ko05410	Hypertrophic cardiomyopathy (HCM)	17/694	100/7206	0.0242867107202
ko04330	Notch signaling pathway	1/694	62/7206	0.0278516560646
ko04211	Longevity regulating pathway	5/694	123/7206	0.0304890632947
ko04930	Type II diabetes mellitus	10/694	54/7206	0.0354371569978
ko05321	Inflammatory bowel disease (IBD)	1/694	56/7206	0.039878983217
ko04668	TNF signaling pathway	5/694	120/7206	0.0411036200921
ko04914	Progesterone-mediated oocyte maturation	4/694	104/7206	0.0432639481002
ko05140	Leishmaniasis	2/694	75/7206	0.0455258751303
ko04110	Cell cycle	7/694	145/7206	0.0460828456012