ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 34/271 145/7206 1.82667657476e-18 ko03030 DNA replication 19/271 38/7206 8.48630339495e-18 ko04110 Cell cycle 33/271 145/7206 1.5983897475e-17 ko04111 Cell cycle - yeast 20/271 90/7206 7.62180116251e-11 ko03008 Ribosome biogenesis in eukaryotes 18/271 79/7206 4.50909810781e-10 ko00240 Pyrimidine metabolism 21/271 110/7206 5.17837030291e-10 ko03013 RNA transport 25/271 166/7206 2.12435612035e-09 ko03410 Base excision repair 12/271 38/7206 7.10106742614e-09 ko03420 Nucleotide excision repair 12/271 46/7206 7.79330883261e-08 ko03015 mRNA surveillance pathway 16/271 93/7206 2.89099130128e-07 ko04113 Meiosis - yeast 13/271 70/7206 1.56916760411e-06 ko04080 Neuroactive ligand-receptor interaction 1/271 423/7206 2.04078699919e-06 ko03020 RNA polymerase 8/271 29/7206 7.78216841465e-06 ko03430 Mismatch repair 7/271 22/7206 1.0334102954e-05 ko05169 Epstein-Barr virus infection 20/271 206/7206 8.71748347668e-05 ko03460 Fanconi anemia pathway 9/271 51/7206 9.99997369152e-05 ko05166 HTLV-I infection 25/271 292/7206 0.000103966548534 ko04218 Cellular senescence 17/271 177/7206 0.000336677827542 ko00230 Purine metabolism 18/271 194/7206 0.000346315260187 ko04020 Calcium signaling pathway 1/271 265/7206 0.000757244507367 ko05222 Small cell lung cancer 10/271 89/7206 0.00176848820342 ko03050 Proteasome 7/271 54/7206 0.00383599716616 ko05206 MicroRNAs in cancer 14/271 177/7206 0.00772837663308 ko05219 Bladder cancer 6/271 48/7206 0.00871169746572 ko05217 Basal cell carcinoma 7/271 68/7206 0.0134673534379 ko04723 Retrograde endocannabinoid signaling 1/271 175/7206 0.0150590740739 ko03450 Non-homologous end-joining 3/271 15/7206 0.0171087690298 ko04022 cGMP-PKG signaling pathway 2/271 216/7206 0.0177801998308 ko04144 Endocytosis 5/271 342/7206 0.0187494256373 ko04340 Hedgehog signaling pathway 6/271 58/7206 0.0210660708013 ko04910 Insulin signaling pathway 1/271 172/7206 0.0226077193945 ko04261 Adrenergic signaling in cardiomyocytes 2/271 205/7206 0.0250137791398 ko04921 Oxytocin signaling pathway 2/271 209/7206 0.0251512044924 ko04612 Antigen processing and presentation 7/271 77/7206 0.0251639010218 ko01522 Endocrine resistance 10/271 124/7206 0.0263239500492 ko04725 Cholinergic synapse 1/271 160/7206 0.032150183424 ko04072 Phospholipase D signaling pathway 2/271 197/7206 0.0351496387148 ko04014 Ras signaling pathway 4/271 279/7206 0.0353822795298 ko04062 Chemokine signaling pathway 2/271 201/7206 0.0357761194743 ko00361 Chlorocyclohexane and chlorobenzene degradation 1/271 1/7206 0.0376075492647 ko00364 Fluorobenzoate degradation 1/271 1/7206 0.0376075492647 ko00623 Toluene degradation 1/271 1/7206 0.0376075492647 ko03018 RNA degradation 7/271 84/7206 0.038068784315 ko04728 Dopaminergic synapse 2/271 185/7206 0.0490007935638