ko pathway ratio_in_study ratio_in_pop p_value ko00120 Primary bile acid biosynthesis 10/480 20/7206 1.57929422727e-07 ko04710 Circadian rhythm 12/480 43/7206 1.52075351964e-05 ko00590 Arachidonic acid metabolism 12/480 52/7206 0.000117928390264 ko04610 Complement and coagulation cascades 15/480 79/7206 0.000184708368145 ko00561 Glycerolipid metabolism 13/480 63/7206 0.000207832858262 ko03013 RNA transport 1/480 166/7206 0.000214922940386 ko00140 Steroid hormone biosynthesis 10/480 41/7206 0.000268211465138 ko04070 Phosphatidylinositol signaling system 18/480 112/7206 0.000391102403472 ko04630 Jak-STAT signaling pathway 20/480 132/7206 0.000524340159819 ko04060 Cytokine-cytokine receptor interaction 26/480 191/7206 0.000536423566024 ko03040 Spliceosome 1/480 145/7206 0.00104370502808 ko04711 Circadian rhythm - fly 5/480 13/7206 0.00105567057627 ko00592 alpha-Linolenic acid metabolism 6/480 19/7206 0.00108769167196 ko00350 Tyrosine metabolism 8/480 33/7206 0.00115037266612 ko00051 Fructose and mannose metabolism 9/480 42/7206 0.00147509368672 ko03010 Ribosome 1/480 129/7206 0.00214751522764 ko04390 Hippo signaling pathway 3/480 188/7206 0.00255094252182 ko00564 Glycerophospholipid metabolism 15/480 99/7206 0.00318957308708 ko05321 Inflammatory bowel disease (IBD) 10/480 56/7206 0.0034633456108 ko04380 Osteoclast differentiation 18/480 134/7206 0.00419608416734 ko05224 Breast cancer 3/480 174/7206 0.00490399050218 ko03320 PPAR signaling pathway 11/480 69/7206 0.00549016732923 ko00565 Ether lipid metabolism 8/480 42/7206 0.00576786679389 ko04922 Glucagon signaling pathway 17/480 128/7206 0.00608066803762 ko04611 Platelet activation 20/480 163/7206 0.00661051048911 ko04072 Phospholipase D signaling pathway 23/480 197/7206 0.008252953941 ko05322 Systemic lupus erythematosus 3/480 151/7206 0.013047525549 ko00591 Linoleic acid metabolism 5/480 22/7206 0.0131225420401 ko04350 TGF-beta signaling pathway 1/480 103/7206 0.0146508332066 ko00330 Arginine and proline metabolism 9/480 61/7206 0.0187086703942 ko00220 Arginine biosynthesis 5/480 24/7206 0.0189819360287 ko00983 Drug metabolism - other enzymes 7/480 42/7206 0.0196499508208 ko05231 Choline metabolism in cancer 16/480 134/7206 0.0211873768684 ko01040 Biosynthesis of unsaturated fatty acids 5/480 25/7206 0.0224661240947 ko04137 Mitophagy - animal 11/480 82/7206 0.0227952638488 ko00360 Phenylalanine metabolism 4/480 17/7206 0.023086959084 ko04020 Calcium signaling pathway 27/480 265/7206 0.0235898975547 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 2/480 4/7206 0.0242782016501 ko00643 Styrene degradation 2/480 4/7206 0.0242782016501 ko00950 Isoquinoline alkaloid biosynthesis 3/480 10/7206 0.024777414077 ko04022 cGMP-PKG signaling pathway 23/480 216/7206 0.0252852090473 ko04930 Type II diabetes mellitus 8/480 54/7206 0.0253416262612 ko04550 Signaling pathways regulating pluripotency of stem cells 4/480 165/7206 0.025417788289 ko00500 Starch and sucrose metabolism 6/480 35/7206 0.0263461474013 ko04925 Aldosterone synthesis and secretion 13/480 105/7206 0.027492608123 ko04111 Cell cycle - yeast 1/480 90/7206 0.0302629649836 ko04310 Wnt signaling pathway 5/480 181/7206 0.0329499706733 ko04672 Intestinal immune network for IgA production 6/480 37/7206 0.0337564525205 ko00982 Drug metabolism - cytochrome P450 6/480 37/7206 0.0337564525205 ko05034 Alcoholism 8/480 238/7206 0.0341625582337 ko04650 Natural killer cell mediated cytotoxicity 12/480 97/7206 0.03641590992 ko02010 ABC transporters 6/480 39/7206 0.0423963056811 ko05340 Primary immunodeficiency 5/480 30/7206 0.0459368867757 ko00100 Steroid biosynthesis 4/480 21/7206 0.0470839127122 ko05200 Pathways in cancer 22/480 492/7206 0.0484528468671 ko05168 Herpes simplex infection 19/480 182/7206 0.04857278379