ko pathway ratio_in_study ratio_in_pop p_value ko04111 Cell cycle - yeast 25/174 90/7206 1.98156715531e-20 ko04110 Cell cycle 30/174 145/7206 2.44925415247e-20 ko04113 Meiosis - yeast 16/174 70/7206 5.34214342492e-12 ko03440 Homologous recombination 12/174 41/7206 1.15545842582e-10 ko03030 DNA replication 11/174 38/7206 8.10930549259e-10 ko03460 Fanconi anemia pathway 10/174 51/7206 2.82447516623e-07 ko05206 MicroRNAs in cancer 16/174 177/7206 5.0205532016e-06 ko03410 Base excision repair 7/174 38/7206 2.84492541554e-05 ko03040 Spliceosome 13/174 145/7206 4.37223551187e-05 ko03008 Ribosome biogenesis in eukaryotes 9/174 79/7206 0.000109265476374 ko03430 Mismatch repair 5/174 22/7206 0.00014619780162 ko00240 Pyrimidine metabolism 10/174 110/7206 0.000303380042912 ko05166 HTLV-I infection 17/174 292/7206 0.000651991079382 ko03420 Nucleotide excision repair 6/174 46/7206 0.000764010686402 ko00310 Lysine degradation 7/174 73/7206 0.00180699883749 ko04330 Notch signaling pathway 6/174 62/7206 0.00364904453319 ko04151 PI3K-Akt signaling pathway 2/174 390/7206 0.00610620880607 ko04218 Cellular senescence 10/174 177/7206 0.0104061261661 ko03018 RNA degradation 6/174 84/7206 0.015642552282 ko05220 Chronic myeloid leukemia 6/174 85/7206 0.0165040403833 ko03013 RNA transport 9/174 166/7206 0.0188520236018 ko05223 Non-small cell lung cancer 5/174 66/7206 0.0211664018539 ko04020 Calcium signaling pathway 1/174 265/7206 0.0222526748604 ko05203 Viral carcinogenesis 13/174 277/7206 0.0244808536821 ko00270 Cysteine and methionine metabolism 4/174 47/7206 0.0261562886506 ko05219 Bladder cancer 4/174 48/7206 0.0280131075411 ko05214 Glioma 5/174 79/7206 0.0416829752026 ko03450 Non-homologous end-joining 2/174 15/7206 0.0495375056786 ko05212 Pancreatic cancer 5/174 83/7206 0.0497863915509