ko pathway ratio_in_study ratio_in_pop p_value ko01200 Carbon metabolism 22/114 128/7206 2.29492102555e-17 ko04260 Cardiac muscle contraction 15/114 98/7206 2.33536211636e-11 ko00710 Carbon fixation in photosynthetic organisms 9/114 27/7206 1.66702448665e-10 ko05410 Hypertrophic cardiomyopathy (HCM) 14/114 100/7206 3.88326144246e-10 ko00010 Glycolysis / Gluconeogenesis 12/114 74/7206 1.31898486929e-09 ko05414 Dilated cardiomyopathy 14/114 112/7206 1.80339318991e-09 ko00620 Pyruvate metabolism 9/114 46/7206 3.04863919531e-08 ko01230 Biosynthesis of amino acids 11/114 85/7206 7.6289204333e-08 ko04261 Adrenergic signaling in cardiomyocytes 16/114 205/7206 1.13179181992e-07 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/114 79/7206 3.80643431588e-07 ko00020 Citrate cycle (TCA cycle) 7/114 35/7206 9.61273307331e-07 ko05416 Viral myocarditis 8/114 55/7206 2.00963911656e-06 ko04020 Calcium signaling pathway 16/114 265/7206 3.59494969639e-06 ko00680 Methane metabolism 6/114 34/7206 1.28750712409e-05 ko04921 Oxytocin signaling pathway 13/114 209/7206 2.31764763204e-05 ko00030 Pentose phosphate pathway 5/114 32/7206 0.000129927956269 ko04022 cGMP-PKG signaling pathway 12/114 216/7206 0.000144688091014 ko00250 Alanine, aspartate and glutamate metabolism 5/114 38/7206 0.00030028134652 ko04922 Glucagon signaling pathway 8/114 128/7206 0.000906322913466 ko04152 AMPK signaling pathway 9/114 161/7206 0.000969233443009 ko00500 Starch and sucrose metabolism 4/114 35/7206 0.00213123420396 ko01212 Fatty acid metabolism 5/114 60/7206 0.00247938528425 ko00630 Glyoxylate and dicarboxylate metabolism 4/114 38/7206 0.00289719757869 ko01210 2-Oxocarboxylic acid metabolism 3/114 20/7206 0.00361282672614 ko00051 Fructose and mannose metabolism 4/114 42/7206 0.00418552816145 ko00071 Fatty acid degradation 4/114 45/7206 0.00537315356041 ko00220 Arginine biosynthesis 3/114 24/7206 0.00612657101619 ko04371 Apelin signaling pathway 8/114 177/7206 0.00681310396995 ko05230 Central carbon metabolism in cancer 5/114 81/7206 0.00895408338249 ko00280 Valine, leucine and isoleucine degradation 4/114 54/7206 0.0102326413264 ko04964 Proximal tubule bicarbonate reclamation 3/114 29/7206 0.0104457215011 ko04270 Vascular smooth muscle contraction 7/114 154/7206 0.0108591481067 ko05010 Alzheimer's disease 8/114 202/7206 0.0144654802182 ko00062 Fatty acid elongation 3/114 33/7206 0.0149018864194 ko00052 Galactose metabolism 3/114 33/7206 0.0149018864194 ko04910 Insulin signaling pathway 7/114 172/7206 0.0189715290697 ko05200 Pathways in cancer 2/114 492/7206 0.0236805249642 ko00310 Lysine degradation 4/114 73/7206 0.0280556506802 ko00720 Carbon fixation pathways in prokaryotes 2/114 17/7206 0.0289004621548 ko00300 Lysine biosynthesis 1/114 2/7206 0.0313921835902 ko00230 Purine metabolism 7/114 194/7206 0.0337549544874 ko00270 Cysteine and methionine metabolism 3/114 47/7206 0.0377965220152 ko00260 Glycine, serine and threonine metabolism 3/114 48/7206 0.0398651193988 ko03018 RNA degradation 4/114 84/7206 0.0436473371254 ko02026 Biofilm formation - Escherichia coli 1/114 3/7206 0.0467199585863