ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	134/828	423/7206	7.56476666671e-31
ko05033	Nicotine addiction	43/828	56/7206	6.3622506661e-30
ko04724	Glutamatergic synapse	73/828	152/7206	7.19613334596e-30
ko05032	Morphine addiction	57/828	110/7206	1.1353986723e-25
ko04727	GABAergic synapse	56/828	110/7206	9.86593935043e-25
ko04713	Circadian entrainment	58/828	136/7206	1.10305350163e-20
ko04723	Retrograde endocannabinoid signaling	66/828	175/7206	6.61771956311e-20
ko04728	Dopaminergic synapse	68/828	185/7206	9.18419551576e-20
ko04725	Cholinergic synapse	60/828	160/7206	4.79711522897e-18
ko04744	Phototransduction	25/828	36/7206	4.00889470977e-16
ko04024	cAMP signaling pathway	77/828	279/7206	4.03348224068e-14
ko04911	Insulin secretion	44/828	117/7206	1.35597275942e-13
ko04721	Synaptic vesicle cycle	33/828	80/7206	8.34810557093e-12
ko04742	Taste transduction	28/828	61/7206	1.45664172821e-11
ko04726	Serotonergic synapse	45/828	137/7206	1.73152302615e-11
ko04921	Oxytocin signaling pathway	59/828	209/7206	2.16806356189e-11
ko04261	Adrenergic signaling in cardiomyocytes	56/828	205/7206	2.27432089985e-10
ko05031	Amphetamine addiction	32/828	91/7206	2.23135805113e-09
ko04720	Long-term potentiation	33/828	99/7206	5.94582647015e-09
ko04020	Calcium signaling pathway	63/828	265/7206	9.99967092151e-09
ko05030	Cocaine addiction	26/828	73/7206	5.35163564844e-08
ko04010	MAPK signaling pathway	69/828	321/7206	1.37810544297e-07
ko03040	Spliceosome	1/828	145/7206	5.44607431198e-07
ko05203	Viral carcinogenesis	9/828	277/7206	1.04405419314e-06
ko04060	Cytokine-cytokine receptor interaction	4/828	191/7206	2.52513359654e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	24/828	79/7206	4.63044032233e-06
ko04514	Cell adhesion molecules (CAMs)	33/828	130/7206	8.87357770233e-06
ko04925	Aldosterone synthesis and secretion	28/828	105/7206	1.50321291638e-05
ko04260	Cardiac muscle contraction	27/828	98/7206	1.51716653971e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	22/828	74/7206	1.68717167318e-05
ko04740	Olfactory transduction	23/828	80/7206	1.99983279534e-05
ko05164	Influenza A	4/828	167/7206	2.19834537097e-05
ko04970	Salivary secretion	26/828	95/7206	2.39720548288e-05
ko05322	Systemic lupus erythematosus	3/828	151/7206	2.46454523818e-05
ko04730	Long-term depression	22/828	78/7206	4.17913608006e-05
ko04022	cGMP-PKG signaling pathway	45/828	216/7206	5.20780326053e-05
ko03013	RNA transport	5/828	166/7206	0.000110655147894
ko04072	Phospholipase D signaling pathway	41/828	197/7206	0.000148342346141
ko04110	Cell cycle	4/828	145/7206	0.000191832634985
ko04621	NOD-like receptor signaling pathway	5/828	157/7206	0.000319670763413
ko05168	Herpes simplex infection	7/828	182/7206	0.000359458492894
ko04141	Protein processing in endoplasmic reticulum	7/828	184/7206	0.0003698398617
ko04120	Ubiquitin mediated proteolysis	4/828	138/7206	0.00038919771061
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/828	14/7206	0.000426823989761
ko05169	Epstein-Barr virus infection	9/828	206/7206	0.000513647028891
ko04350	TGF-beta signaling pathway	2/828	103/7206	0.000524440190893
ko05162	Measles	3/828	120/7206	0.000707048559148
ko04360	Axon guidance	44/828	233/7206	0.000755609769861
ko04745	Phototransduction - fly	12/828	38/7206	0.000772395895775
ko04972	Pancreatic secretion	25/828	111/7206	0.000788356903332
ko04070	Phosphatidylinositol signaling system	25/828	112/7206	0.000871164026433
ko05414	Dilated cardiomyopathy	25/828	112/7206	0.000871164026433
ko05205	Proteoglycans in cancer	15/828	271/7206	0.000905733357905
ko03008	Ribosome biogenesis in eukaryotes	1/828	79/7206	0.00115298854356
ko04612	Antigen processing and presentation	1/828	77/7206	0.00175262862635
ko04971	Gastric acid secretion	22/828	98/7206	0.00196114110368
ko05410	Hypertrophic cardiomyopathy (HCM)	22/828	100/7206	0.00229965080237
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/828	182/7206	0.00305821022728
ko04064	NF-kappa B signaling pathway	3/828	96/7206	0.0056304779029
ko04510	Focal adhesion	15/828	240/7206	0.00727268095973
ko05161	Hepatitis B	9/828	173/7206	0.00739454361592
ko04930	Type II diabetes mellitus	13/828	54/7206	0.00823115509297
ko04630	Jak-STAT signaling pathway	6/828	132/7206	0.00836393838893
ko04640	Hematopoietic cell lineage	1/828	64/7206	0.00869830937372
ko04924	Renin secretion	18/828	86/7206	0.00990147746078
ko05140	Leishmaniasis	2/828	75/7206	0.0101237460982
ko04915	Estrogen signaling pathway	25/828	131/7206	0.0118393523809
ko04140	Autophagy - animal	9/828	164/7206	0.0126444000737
ko04150	mTOR signaling pathway	11/828	184/7206	0.0138217586179
ko04964	Proximal tubule bicarbonate reclamation	8/828	29/7206	0.0139196989357
ko04214	Apoptosis - fly	2/828	72/7206	0.0145700190885
ko05145	Toxoplasmosis	6/828	126/7206	0.0155346571913
ko03018	RNA degradation	3/828	84/7206	0.0157101627421
ko05215	Prostate cancer	5/828	111/7206	0.0158173590177
ko00240	Pyrimidine metabolism	5/828	110/7206	0.015830504318
ko04014	Ras signaling pathway	45/828	279/7206	0.0164800394605
ko03320	PPAR signaling pathway	2/828	69/7206	0.0210010385598
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/828	15/7206	0.0221926696259
ko05034	Alcoholism	39/828	238/7206	0.0223140569087
ko04142	Lysosome	9/828	151/7206	0.0280722559313
ko05418	Fluid shear stress and atherosclerosis	11/828	173/7206	0.0295596349083
ko05166	HTLV-I infection	22/828	292/7206	0.030746423986
ko04062	Chemokine signaling pathway	33/828	201/7206	0.0324593445322
ko00270	Cysteine and methionine metabolism	1/828	47/7206	0.0380052629483
ko05016	Huntington's disease	15/828	215/7206	0.0382552153175
ko00260	Glycine, serine and threonine metabolism	1/828	48/7206	0.0383316589801
ko04657	IL-17 signaling pathway	4/828	87/7206	0.041331333884
ko05133	Pertussis	4/828	87/7206	0.041331333884
ko00512	Mucin type O-glycan biosynthesis	7/828	29/7206	0.0419217907114
ko00330	Arginine and proline metabolism	2/828	61/7206	0.0420620179433
ko04146	Peroxisome	4/828	89/7206	0.0423679071574
ko05222	Small cell lung cancer	4/828	89/7206	0.0423679071574
ko04371	Apelin signaling pathway	29/828	177/7206	0.0426234087158
ko04217	Necroptosis	12/828	178/7206	0.0428528297441
ko04210	Apoptosis	12/828	180/7206	0.043190848553
ko01524	Platinum drug resistance	3/828	76/7206	0.0438316943944
ko04540	Gap junction	22/828	128/7206	0.0493240919682