ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	162/846	423/7206	1.11450923612e-48
ko05033	Nicotine addiction	45/846	56/7206	1.98106091217e-32
ko04724	Glutamatergic synapse	75/846	152/7206	4.96214887518e-31
ko05032	Morphine addiction	54/846	110/7206	1.89297296938e-22
ko04713	Circadian entrainment	60/846	136/7206	8.51320100058e-22
ko04727	GABAergic synapse	52/846	110/7206	1.04593524331e-20
ko04728	Dopaminergic synapse	70/846	185/7206	1.30848514131e-20
ko04723	Retrograde endocannabinoid signaling	67/846	175/7206	4.3151038008e-20
ko04725	Cholinergic synapse	60/846	160/7206	1.3843787862e-17
ko04721	Synaptic vesicle cycle	39/846	80/7206	2.10642304799e-16
ko04020	Calcium signaling pathway	79/846	265/7206	5.30528756768e-16
ko04024	cAMP signaling pathway	81/846	279/7206	1.55241051754e-15
ko04911	Insulin secretion	47/846	117/7206	2.26135996815e-15
ko04726	Serotonergic synapse	49/846	137/7206	1.21507185345e-13
ko04921	Oxytocin signaling pathway	62/846	209/7206	1.1299927937e-12
ko04720	Long-term potentiation	39/846	99/7206	1.20558782138e-12
ko05031	Amphetamine addiction	37/846	91/7206	1.47068454515e-12
ko04742	Taste transduction	29/846	61/7206	3.57554518153e-12
ko04261	Adrenergic signaling in cardiomyocytes	58/846	205/7206	5.78845378175e-11
ko04925	Aldosterone synthesis and secretion	35/846	105/7206	3.64973999774e-09
ko04971	Gastric acid secretion	32/846	98/7206	3.01258993092e-08
ko04970	Salivary secretion	31/846	95/7206	5.04357862201e-08
ko05030	Cocaine addiction	26/846	73/7206	8.3202819721e-08
ko05203	Viral carcinogenesis	8/846	277/7206	1.03156802389e-07
ko03040	Spliceosome	1/846	145/7206	3.51728317222e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	25/846	74/7206	4.74298103071e-07
ko04744	Phototransduction	16/846	36/7206	8.47508314142e-07
ko04514	Cell adhesion molecules (CAMs)	35/846	130/7206	1.45049710445e-06
ko04745	Phototransduction - fly	16/846	38/7206	2.05280187151e-06
ko05164	Influenza A	3/846	167/7206	2.40996790624e-06
ko04010	MAPK signaling pathway	66/846	321/7206	3.18131759611e-06
ko05168	Herpes simplex infection	4/846	182/7206	3.41553265425e-06
ko04730	Long-term depression	24/846	78/7206	5.27348607272e-06
ko04972	Pancreatic secretion	30/846	111/7206	7.99029723375e-06
ko04540	Gap junction	33/846	128/7206	9.42933881783e-06
ko05162	Measles	1/846	120/7206	9.53651517104e-06
ko04750	Inflammatory mediator regulation of TRP channels	31/846	122/7206	2.32992644028e-05
ko04072	Phospholipase D signaling pathway	43/846	197/7206	4.20555224617e-05
ko04120	Ubiquitin mediated proteolysis	3/846	138/7206	7.56491794191e-05
ko04070	Phosphatidylinositol signaling system	28/846	112/7206	7.91922619404e-05
ko05322	Systemic lupus erythematosus	4/846	151/7206	9.42509693205e-05
ko04022	cGMP-PKG signaling pathway	45/846	216/7206	9.42756721517e-05
ko04740	Olfactory transduction	22/846	80/7206	0.000131586675787
ko04060	Cytokine-cytokine receptor interaction	7/846	191/7206	0.000136452010239
ko03013	RNA transport	6/846	166/7206	0.000338172878571
ko04260	Cardiac muscle contraction	24/846	98/7206	0.00036852516315
ko05169	Epstein-Barr virus infection	9/846	206/7206	0.000376893094186
ko04626	Plant-pathogen interaction	8/846	18/7206	0.000518149078247
ko04014	Ras signaling pathway	52/846	279/7206	0.000587394939104
ko04110	Cell cycle	5/846	145/7206	0.000608496905315
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	20/846	79/7206	0.000650635907728
ko04621	NOD-like receptor signaling pathway	6/846	157/7206	0.000651245699917
ko04612	Antigen processing and presentation	1/846	77/7206	0.00113708075796
ko03008	Ribosome biogenesis in eukaryotes	1/846	79/7206	0.00117215763563
ko04966	Collecting duct acid secretion	9/846	26/7206	0.00198284106601
ko04141	Protein processing in endoplasmic reticulum	9/846	184/7206	0.00231300421164
ko04360	Axon guidance	43/846	233/7206	0.00249537656839
ko04915	Estrogen signaling pathway	27/846	131/7206	0.00353618790439
ko05166	HTLV-I infection	19/846	292/7206	0.00380810738817
ko04912	GnRH signaling pathway	25/846	122/7206	0.00435383812551
ko04964	Proximal tubule bicarbonate reclamation	9/846	29/7206	0.00459768518572
ko05161	Hepatitis B	9/846	173/7206	0.00551876252024
ko04630	Jak-STAT signaling pathway	6/846	132/7206	0.00607897052379
ko05205	Proteoglycans in cancer	18/846	271/7206	0.00678487097215
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/846	182/7206	0.00682792940584
ko05414	Dilated cardiomyopathy	23/846	112/7206	0.00697883506689
ko04610	Complement and coagulation cascades	2/846	79/7206	0.00722117135103
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/846	59/7206	0.00773879827916
ko04330	Notch signaling pathway	1/846	62/7206	0.00839071099301
ko04550	Signaling pathways regulating pluripotency of stem cells	9/846	165/7206	0.00959632786836
ko00310	Lysine degradation	2/846	73/7206	0.0100276580042
ko04916	Melanogenesis	27/846	142/7206	0.0115190993232
ko04146	Peroxisome	3/846	89/7206	0.0115597081003
ko04976	Bile secretion	17/846	80/7206	0.0132635603286
ko04214	Apoptosis - fly	2/846	72/7206	0.0148972969743
ko04114	Oocyte meiosis	26/846	139/7206	0.0157034952957
ko05215	Prostate cancer	5/846	111/7206	0.016161411706
ko05110	Vibrio cholerae infection	14/846	63/7206	0.0163636725404
ko04924	Renin secretion	18/846	86/7206	0.0165216765213
ko04015	Rap1 signaling pathway	46/846	278/7206	0.0170242243415
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/846	14/7206	0.0177970764751
ko00562	Inositol phosphate metabolism	18/846	89/7206	0.0190172517096
ko04140	Autophagy - animal	10/846	164/7206	0.0195290218169
ko00590	Arachidonic acid metabolism	1/846	52/7206	0.0270737850145
ko04918	Thyroid hormone synthesis	17/846	86/7206	0.0272904160661
ko05231	Choline metabolism in cancer	24/846	134/7206	0.0300265355519
ko05140	Leishmaniasis	3/846	75/7206	0.0304114660181
ko01524	Platinum drug resistance	3/846	76/7206	0.0304499468517
ko04270	Vascular smooth muscle contraction	27/846	154/7206	0.0306749262689
ko04371	Apelin signaling pathway	30/846	177/7206	0.0333448913204
ko00240	Pyrimidine metabolism	6/846	110/7206	0.0362281816195
ko00620	Pyruvate metabolism	1/846	46/7206	0.0377513115597
ko03420	Nucleotide excision repair	1/846	46/7206	0.0377513115597
ko00260	Glycine, serine and threonine metabolism	1/846	48/7206	0.0389673992536
ko05219	Bladder cancer	1/846	48/7206	0.0389673992536
ko04510	Focal adhesion	18/846	240/7206	0.04066544283
ko05220	Chronic myeloid leukemia	4/846	85/7206	0.041043544275
ko05010	Alzheimer's disease	33/846	202/7206	0.0455259143763