ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	93/536	423/7206	5.40288002129e-23
ko05033	Nicotine addiction	32/536	56/7206	2.57039282587e-22
ko04724	Glutamatergic synapse	51/536	152/7206	2.36103897226e-21
ko04721	Synaptic vesicle cycle	33/536	80/7206	2.60567317125e-17
ko04728	Dopaminergic synapse	48/536	185/7206	4.31907772734e-15
ko04723	Retrograde endocannabinoid signaling	43/536	175/7206	9.55596356401e-13
ko05032	Morphine addiction	33/536	110/7206	1.23259759341e-12
ko04727	GABAergic synapse	32/536	110/7206	6.88612994502e-12
ko04713	Circadian entrainment	35/536	136/7206	3.33206355457e-11
ko05014	Amyotrophic lateral sclerosis (ALS)	23/536	74/7206	1.57613186985e-09
ko05030	Cocaine addiction	22/536	73/7206	6.85765472467e-09
ko04911	Insulin secretion	28/536	117/7206	1.86012613443e-08
ko05031	Amphetamine addiction	24/536	91/7206	2.62153885059e-08
ko04024	cAMP signaling pathway	48/536	279/7206	3.02276050666e-08
ko04726	Serotonergic synapse	29/536	137/7206	1.85977028094e-07
ko04514	Cell adhesion molecules (CAMs)	27/536	130/7206	7.38424672595e-07
ko04725	Cholinergic synapse	30/536	160/7206	1.77653685392e-06
ko04261	Adrenergic signaling in cardiomyocytes	33/536	205/7206	1.88730549732e-05
ko04010	MAPK signaling pathway	45/536	321/7206	2.7511870042e-05
ko04742	Taste transduction	15/536	61/7206	2.76756127019e-05
ko04720	Long-term potentiation	20/536	99/7206	3.11601892496e-05
ko05164	Influenza A	1/536	167/7206	6.62004796311e-05
ko04060	Cytokine-cytokine receptor interaction	2/536	191/7206	7.03511919407e-05
ko04360	Axon guidance	34/536	233/7206	0.000115796831117
ko04970	Salivary secretion	18/536	95/7206	0.000182923837705
ko05205	Proteoglycans in cancer	6/536	271/7206	0.000217901478565
ko04921	Oxytocin signaling pathway	31/536	209/7206	0.000226103203848
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/536	14/7206	0.00029493836816
ko03040	Spliceosome	1/536	145/7206	0.000310117901969
ko04966	Collecting duct acid secretion	8/536	26/7206	0.00041788221259
ko04120	Ubiquitin mediated proteolysis	1/536	138/7206	0.000447861162723
ko04730	Long-term depression	15/536	78/7206	0.000526414672316
ko04972	Pancreatic secretion	18/536	111/7206	0.00145861401179
ko05203	Viral carcinogenesis	8/536	277/7206	0.00151893339285
ko05110	Vibrio cholerae infection	12/536	63/7206	0.00202968288453
ko04540	Gap junction	19/536	128/7206	0.0032804321646
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/536	59/7206	0.00366970813372
ko04932	Non-alcoholic fatty liver disease (NAFLD)	4/536	182/7206	0.00371630193438
ko04510	Focal adhesion	7/536	240/7206	0.00379756990778
ko04020	Calcium signaling pathway	32/536	265/7206	0.00575270867451
ko04260	Cardiac muscle contraction	15/536	98/7206	0.00603283592055
ko04971	Gastric acid secretion	15/536	98/7206	0.00603283592055
ko04211	Longevity regulating pathway	2/536	123/7206	0.00829036734764
ko05120	Epithelial cell signaling in Helicobacter pylori infection	14/536	92/7206	0.00840945178324
ko05168	Herpes simplex infection	5/536	182/7206	0.00968743958148
ko03013	RNA transport	4/536	166/7206	0.00991989128011
ko05166	HTLV-I infection	11/536	292/7206	0.0118642921283
ko04621	NOD-like receptor signaling pathway	4/536	157/7206	0.0132134656644
ko04146	Peroxisome	1/536	89/7206	0.0137952287275
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	12/536	79/7206	0.0153353255359
ko00240	Pyrimidine metabolism	2/536	110/7206	0.016492099508
ko00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/536	8/7206	0.0172721197206
ko05322	Systemic lupus erythematosus	4/536	151/7206	0.0180696425899
ko05220	Chronic myeloid leukemia	1/536	85/7206	0.0202108362019
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	4/536	15/7206	0.0213513972957
ko05169	Epstein-Barr virus infection	7/536	206/7206	0.0213871679194
ko04145	Phagosome	20/536	162/7206	0.02223513557
ko05034	Alcoholism	27/536	238/7206	0.023689434712
ko04022	cGMP-PKG signaling pathway	25/536	216/7206	0.0245208783922
ko01200	Carbon metabolism	3/536	128/7206	0.025146775881
ko03008	Ribosome biogenesis in eukaryotes	1/536	79/7206	0.0291656931398
ko04141	Protein processing in endoplasmic reticulum	6/536	184/7206	0.0310942336921
ko04611	Platelet activation	5/536	163/7206	0.0327316552946
ko05146	Amoebiasis	2/536	99/7206	0.0328531165294
ko04140	Autophagy - animal	5/536	164/7206	0.0331169678119
ko00513	Various types of N-glycan biosynthesis	7/536	42/7206	0.0335265675138
ko05016	Huntington's disease	8/536	215/7206	0.0338476887508
ko04924	Renin secretion	12/536	86/7206	0.0345592569383
ko05161	Hepatitis B	6/536	173/7206	0.0399177614541
ko01524	Platinum drug resistance	1/536	76/7206	0.0435609197633
ko04612	Antigen processing and presentation	1/536	77/7206	0.044499398774