ko pathway ratio_in_study ratio_in_pop p_value ko04724 Glutamatergic synapse 23/255 152/7206 2.7126517988e-09 ko04728 Dopaminergic synapse 25/255 185/7206 5.94896212751e-09 ko04721 Synaptic vesicle cycle 15/255 80/7206 9.58146398665e-08 ko04911 Insulin secretion 17/255 117/7206 6.28944876962e-07 ko04725 Cholinergic synapse 19/255 160/7206 3.19137752113e-06 ko04713 Circadian entrainment 17/255 136/7206 5.30397296283e-06 ko04360 Axon guidance 22/255 233/7206 2.31426860325e-05 ko04744 Phototransduction 8/255 36/7206 2.81817290678e-05 ko04720 Long-term potentiation 13/255 99/7206 4.10764120864e-05 ko04745 Phototransduction - fly 8/255 38/7206 4.28313161803e-05 ko04726 Serotonergic synapse 15/255 137/7206 9.19172144474e-05 ko04727 GABAergic synapse 13/255 110/7206 0.000124471427006 ko04966 Collecting duct acid secretion 6/255 26/7206 0.000234640115655 ko04964 Proximal tubule bicarbonate reclamation 6/255 29/7206 0.000442804808454 ko05033 Nicotine addiction 8/255 56/7206 0.000717261150615 ko04723 Retrograde endocannabinoid signaling 15/255 175/7206 0.0012993207771 ko05031 Amphetamine addiction 10/255 91/7206 0.00132915860777 ko05110 Vibrio cholerae infection 8/255 63/7206 0.00158018845914 ko04024 cAMP signaling pathway 20/255 279/7206 0.00242641089992 ko04261 Adrenergic signaling in cardiomyocytes 16/255 205/7206 0.00296140570714 ko05030 Cocaine addiction 8/255 73/7206 0.00404933499134 ko05014 Amyotrophic lateral sclerosis (ALS) 8/255 74/7206 0.00440481875997 ko04072 Phospholipase D signaling pathway 15/255 197/7206 0.00486815416088 ko04940 Type I diabetes mellitus 5/255 32/7206 0.00490910891272 ko05032 Morphine addiction 10/255 110/7206 0.00539858478234 ko04972 Pancreatic secretion 10/255 111/7206 0.00575349315398 ko04070 Phosphatidylinositol signaling system 10/255 112/7206 0.00612638013643 ko04970 Salivary secretion 9/255 95/7206 0.00624203906342 ko05230 Central carbon metabolism in cancer 8/255 81/7206 0.00760875054567 ko04971 Gastric acid secretion 9/255 98/7206 0.0076296825434 ko04930 Type II diabetes mellitus 6/255 54/7206 0.0115272496083 ko04014 Ras signaling pathway 18/255 279/7206 0.0122291814154 ko04391 Hippo signaling pathway - fly 8/255 90/7206 0.013986791081 ko04960 Aldosterone-regulated sodium reabsorption 5/255 41/7206 0.0141227885944 ko02024 Quorum sensing 3/255 15/7206 0.0145332952458 ko04071 Sphingolipid signaling pathway 12/255 162/7206 0.0148367232302 ko04060 Cytokine-cytokine receptor interaction 1/255 191/7206 0.0153161103264 ko04973 Carbohydrate digestion and absorption 5/255 42/7206 0.0155814250294 ko05120 Epithelial cell signaling in Helicobacter pylori infection 8/255 92/7206 0.0158171252282 ko04020 Calcium signaling pathway 17/255 265/7206 0.0162705018645 ko04961 Endocrine and other factor-regulated calcium reabsorption 6/255 59/7206 0.0173834794724 ko05010 Alzheimer's disease 14/255 202/7206 0.0175722690123 ko04080 Neuroactive ligand-receptor interaction 24/255 423/7206 0.0202565947601 ko04740 Olfactory transduction 7/255 80/7206 0.0226262305625 ko04626 Plant-pathogen interaction 3/255 18/7206 0.0241102210858 ko04514 Cell adhesion molecules (CAMs) 10/255 130/7206 0.0254703992672 ko00062 Fatty acid elongation 4/255 33/7206 0.0279968302844 ko04015 Rap1 signaling pathway 17/255 278/7206 0.0289720649664 ko04062 Chemokine signaling pathway 13/255 201/7206 0.0313228794823 ko04924 Renin secretion 7/255 86/7206 0.0320735671976 ko04925 Aldosterone synthesis and secretion 8/255 105/7206 0.0321270245848 ko02025 Biofilm formation - Pseudomonas aeruginosa 1/255 1/7206 0.0353871773522 ko04750 Inflammatory mediator regulation of TRP channels 9/255 122/7206 0.0404544300001 ko05152 Tuberculosis 12/255 187/7206 0.041895482544 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/255 191/7206 0.0457807327417 ko04144 Endocytosis 19/255 342/7206 0.0493570134867