ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	113/846	423/7206	2.97703396202e-18
ko04724	Glutamatergic synapse	51/846	152/7206	6.78989518063e-13
ko04713	Circadian entrainment	47/846	136/7206	1.65620465789e-12
ko04020	Calcium signaling pathway	71/846	265/7206	7.33701846654e-12
ko04727	GABAergic synapse	35/846	110/7206	1.44495385725e-08
ko05032	Morphine addiction	35/846	110/7206	1.44495385725e-08
ko04022	cGMP-PKG signaling pathway	55/846	216/7206	1.73999306464e-08
ko04725	Cholinergic synapse	44/846	160/7206	3.21239409994e-08
ko04970	Salivary secretion	31/846	95/7206	5.04357862201e-08
ko04921	Oxytocin signaling pathway	52/846	209/7206	7.96480170072e-08
ko05033	Nicotine addiction	22/846	56/7206	1.11182472905e-07
ko04726	Serotonergic synapse	38/846	137/7206	2.42218756043e-07
ko04911	Insulin secretion	34/846	117/7206	2.76460348576e-07
ko04728	Dopaminergic synapse	46/846	185/7206	5.95181560308e-07
ko04024	cAMP signaling pathway	61/846	279/7206	9.15751820174e-07
ko05322	Systemic lupus erythematosus	2/846	151/7206	2.30122809421e-06
ko03010	Ribosome	1/846	129/7206	2.72735168544e-06
ko04710	Circadian rhythm	17/846	43/7206	2.8172338291e-06
ko04971	Gastric acid secretion	28/846	98/7206	4.48503820468e-06
ko03040	Spliceosome	2/846	145/7206	5.21687965771e-06
ko04270	Vascular smooth muscle contraction	38/846	154/7206	5.79018974796e-06
ko04925	Aldosterone synthesis and secretion	29/846	105/7206	8.19337230996e-06
ko05031	Amphetamine addiction	26/846	91/7206	9.79671752849e-06
ko04922	Glucagon signaling pathway	32/846	128/7206	2.24451399841e-05
ko03013	RNA transport	4/846	166/7206	2.2753375432e-05
ko04721	Synaptic vesicle cycle	23/846	80/7206	2.83728289212e-05
ko04371	Apelin signaling pathway	40/846	177/7206	4.1926687297e-05
ko04745	Phototransduction - fly	14/846	38/7206	5.43643140049e-05
ko04261	Adrenergic signaling in cardiomyocytes	44/846	205/7206	5.79510630939e-05
ko04730	Long-term depression	22/846	78/7206	5.81815604592e-05
ko04723	Retrograde endocannabinoid signaling	39/846	175/7206	6.54441667022e-05
ko04720	Long-term potentiation	25/846	99/7206	0.000192898044649
ko04110	Cell cycle	4/846	145/7206	0.000199617369405
ko05203	Viral carcinogenesis	15/846	277/7206	0.000391660265812
ko04742	Taste transduction	17/846	61/7206	0.000462466442922
ko04514	Cell adhesion molecules (CAMs)	29/846	130/7206	0.000502523420012
ko04070	Phosphatidylinositol signaling system	26/846	112/7206	0.000528590620164
ko05168	Herpes simplex infection	8/846	182/7206	0.00095462884909
ko04924	Renin secretion	21/846	86/7206	0.000998120517863
ko04141	Protein processing in endoplasmic reticulum	9/846	184/7206	0.00231300421164
ko04144	Endocytosis	23/846	342/7206	0.00246369083971
ko04972	Pancreatic secretion	24/846	111/7206	0.00259362365294
ko00010	Glycolysis / Gluconeogenesis	18/846	74/7206	0.00282825609292
ko04626	Plant-pathogen interaction	7/846	18/7206	0.00296462897662
ko04750	Inflammatory mediator regulation of TRP channels	25/846	122/7206	0.00435383812551
ko04964	Proximal tubule bicarbonate reclamation	9/846	29/7206	0.00459768518572
ko01230	Biosynthesis of amino acids	19/846	85/7206	0.00563945296465
ko05169	Epstein-Barr virus infection	12/846	206/7206	0.00573270206762
ko00120	Primary bile acid biosynthesis	7/846	20/7206	0.00585241983001
ko04960	Aldosterone-regulated sodium reabsorption	11/846	41/7206	0.00623176534709
ko04966	Collecting duct acid secretion	8/846	26/7206	0.00786632317286
ko00710	Carbon fixation in photosynthetic organisms	8/846	27/7206	0.0100544506335
ko04120	Ubiquitin mediated proteolysis	7/846	138/7206	0.010721498004
ko04260	Cardiac muscle contraction	20/846	98/7206	0.0110846779753
ko04657	IL-17 signaling pathway	3/846	87/7206	0.0111169518346
ko04916	Melanogenesis	27/846	142/7206	0.0115190993232
ko01200	Carbon metabolism	25/846	128/7206	0.011671445726
ko04540	Gap junction	25/846	128/7206	0.011671445726
ko04360	Axon guidance	40/846	233/7206	0.0126192903866
ko04014	Ras signaling pathway	46/846	279/7206	0.0172247705002
ko03050	Proteasome	1/846	54/7206	0.0176992401505
ko00520	Amino sugar and nucleotide sugar metabolism	1/846	55/7206	0.0181420285011
ko05164	Influenza A	10/846	167/7206	0.0199290521342
ko05166	HTLV-I infection	22/846	292/7206	0.0202312948038
ko05014	Amyotrophic lateral sclerosis (ALS)	15/846	74/7206	0.0286983033811
ko04744	Phototransduction	9/846	36/7206	0.0314601324057
ko04740	Olfactory transduction	16/846	80/7206	0.0335265431998
ko04217	Necroptosis	12/846	178/7206	0.0336045573723
ko04210	Apoptosis	12/846	180/7206	0.0338842665125
ko04919	Thyroid hormone signaling pathway	25/846	143/7206	0.0357747505572
ko00240	Pyrimidine metabolism	6/846	110/7206	0.0362281816195
ko03420	Nucleotide excision repair	1/846	46/7206	0.0377513115597
ko04630	Jak-STAT signaling pathway	8/846	132/7206	0.0399985727876
ko05220	Chronic myeloid leukemia	4/846	85/7206	0.041043544275
ko00230	Purine metabolism	32/846	194/7206	0.0416798423644
ko05110	Vibrio cholerae infection	13/846	63/7206	0.0454926101898
ko05010	Alzheimer's disease	33/846	202/7206	0.0455259143763