ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	58/612	152/7206	1.70210320951e-24
ko05033	Nicotine addiction	34/612	56/7206	5.85759290204e-23
ko04080	Neuroactive ligand-receptor interaction	95/612	423/7206	6.74221120553e-20
ko04721	Synaptic vesicle cycle	36/612	80/7206	2.13828993193e-18
ko04728	Dopaminergic synapse	54/612	185/7206	9.25487200073e-17
ko04727	GABAergic synapse	40/612	110/7206	2.41317053196e-16
ko05032	Morphine addiction	40/612	110/7206	2.41317053196e-16
ko04713	Circadian entrainment	43/612	136/7206	6.15605693307e-15
ko04723	Retrograde endocannabinoid signaling	49/612	175/7206	1.6253371665e-14
ko04725	Cholinergic synapse	42/612	160/7206	1.36613451316e-11
ko04911	Insulin secretion	34/612	117/7206	6.35587629829e-11
ko04024	cAMP signaling pathway	57/612	279/7206	1.91652525766e-10
ko04261	Adrenergic signaling in cardiomyocytes	43/612	205/7206	2.49024245567e-08
ko04921	Oxytocin signaling pathway	43/612	209/7206	3.46702885941e-08
ko05030	Cocaine addiction	22/612	73/7206	7.69972171213e-08
ko04514	Cell adhesion molecules (CAMs)	30/612	130/7206	2.79563207082e-07
ko04726	Serotonergic synapse	31/612	137/7206	2.82821578539e-07
ko05031	Amphetamine addiction	24/612	91/7206	3.25242770178e-07
ko04010	MAPK signaling pathway	53/612	321/7206	1.70015774968e-06
ko04720	Long-term potentiation	24/612	99/7206	1.71813985166e-06
ko04020	Calcium signaling pathway	46/612	265/7206	2.52075331774e-06
ko04970	Salivary secretion	23/612	95/7206	2.89310602728e-06
ko04744	Phototransduction	13/612	36/7206	3.88728946727e-06
ko04060	Cytokine-cytokine receptor interaction	2/612	191/7206	9.80307995298e-06
ko04730	Long-term depression	19/612	78/7206	1.91707851358e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	18/612	74/7206	3.23251553722e-05
ko04972	Pancreatic secretion	23/612	111/7206	4.43266517687e-05
ko03040	Spliceosome	1/612	145/7206	6.00145296677e-05
ko05203	Viral carcinogenesis	7/612	277/7206	6.04775997459e-05
ko05164	Influenza A	2/612	167/7206	0.00010206859934
ko04966	Collecting duct acid secretion	9/612	26/7206	0.000180966911018
ko04742	Taste transduction	14/612	61/7206	0.000460244951649
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/612	14/7206	0.000607349648704
ko04360	Axon guidance	35/612	233/7206	0.000740244256686
ko04022	cGMP-PKG signaling pathway	33/612	216/7206	0.000747036463692
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	16/612	79/7206	0.00082020203604
ko04120	Ubiquitin mediated proteolysis	2/612	138/7206	0.000939073404335
ko04071	Sphingolipid signaling pathway	26/612	162/7206	0.00143940389846
ko04260	Cardiac muscle contraction	18/612	98/7206	0.00148459700683
ko05322	Systemic lupus erythematosus	3/612	151/7206	0.00163000725415
ko03013	RNA transport	4/612	166/7206	0.00180165846628
ko05169	Epstein-Barr virus infection	6/612	206/7206	0.00205725752617
ko05110	Vibrio cholerae infection	13/612	63/7206	0.00207049828192
ko04964	Proximal tubule bicarbonate reclamation	8/612	29/7206	0.00222361802252
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/612	182/7206	0.00270503053758
ko04961	Endocrine and other factor-regulated calcium reabsorption	12/612	59/7206	0.00344656582599
ko04925	Aldosterone synthesis and secretion	18/612	105/7206	0.0038644121537
ko04072	Phospholipase D signaling pathway	29/612	197/7206	0.00389668291134
ko04924	Renin secretion	15/612	86/7206	0.00587056626007
ko05168	Herpes simplex infection	6/612	182/7206	0.00683951835935
ko05120	Epithelial cell signaling in Helicobacter pylori infection	16/612	92/7206	0.0068621165118
ko04141	Protein processing in endoplasmic reticulum	6/612	184/7206	0.00687871317202
ko04971	Gastric acid secretion	16/612	98/7206	0.00956987460091
ko04915	Estrogen signaling pathway	20/612	131/7206	0.0101545281659
ko05162	Measles	3/612	120/7206	0.0124108593425
ko04144	Endocytosis	42/612	342/7206	0.0128456799507
ko04621	NOD-like receptor signaling pathway	5/612	157/7206	0.0129322076035
ko05205	Proteoglycans in cancer	12/612	271/7206	0.013892237815
ko04070	Phosphatidylinositol signaling system	17/612	112/7206	0.0159691693831
ko04630	Jak-STAT signaling pathway	4/612	132/7206	0.0175667694031
ko00310	Lysine degradation	1/612	73/7206	0.0194370636561
ko04612	Antigen processing and presentation	1/612	77/7206	0.0206707781456
ko04140	Autophagy - animal	6/612	164/7206	0.0223662534545
ko00240	Pyrimidine metabolism	3/612	110/7206	0.0239829047069
ko05215	Prostate cancer	3/612	111/7206	0.024153756436
ko05166	HTLV-I infection	15/612	292/7206	0.0321730472236
ko04146	Peroxisome	2/612	89/7206	0.0326881528887
ko04211	Longevity regulating pathway	4/612	123/7206	0.0327562493268
ko05161	Hepatitis B	7/612	173/7206	0.0368062467887
ko05414	Dilated cardiomyopathy	16/612	112/7206	0.037994201471
ko04745	Phototransduction - fly	7/612	38/7206	0.0383471219718
ko04640	Hematopoietic cell lineage	1/612	64/7206	0.0410675092233
ko04930	Type II diabetes mellitus	9/612	54/7206	0.0446219640254
ko04137	Mitophagy - animal	2/612	82/7206	0.0451049423918
ko04510	Focal adhesion	12/612	240/7206	0.0454395700623
ko04350	TGF-beta signaling pathway	3/612	103/7206	0.0471381322448
ko04550	Signaling pathways regulating pluripotency of stem cells	7/612	165/7206	0.0471935616974
ko04068	FoxO signaling pathway	7/612	167/7206	0.047678955043
ko04014	Ras signaling pathway	33/612	279/7206	0.0480783344826