ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	187/1047	423/7206	7.08836616095e-53
ko04724	Glutamatergic synapse	88/1047	152/7206	4.28779937069e-36
ko05033	Nicotine addiction	49/1047	56/7206	2.78232621618e-34
ko04727	GABAergic synapse	68/1047	110/7206	1.61783144633e-30
ko05032	Morphine addiction	65/1047	110/7206	1.40322663074e-27
ko04713	Circadian entrainment	70/1047	136/7206	1.13921963598e-24
ko04723	Retrograde endocannabinoid signaling	76/1047	175/7206	7.16929847163e-21
ko04721	Synaptic vesicle cycle	46/1047	80/7206	3.62609930965e-19
ko04728	Dopaminergic synapse	76/1047	185/7206	3.94339742897e-19
ko04725	Cholinergic synapse	67/1047	160/7206	1.6502684093e-17
ko04742	Taste transduction	37/1047	61/7206	9.99685362161e-17
ko04744	Phototransduction	27/1047	36/7206	4.4998429855e-16
ko04024	cAMP signaling pathway	91/1047	279/7206	5.78573555175e-15
ko04726	Serotonergic synapse	56/1047	137/7206	2.79706942787e-14
ko04911	Insulin secretion	50/1047	117/7206	8.71890116884e-14
ko04020	Calcium signaling pathway	85/1047	265/7206	2.02233840662e-13
ko04740	Olfactory transduction	36/1047	80/7206	4.51194377016e-11
ko04921	Oxytocin signaling pathway	67/1047	209/7206	8.57884145307e-11
ko05203	Viral carcinogenesis	10/1047	277/7206	2.81005529444e-09
ko05031	Amphetamine addiction	36/1047	91/7206	3.52336240127e-09
ko04261	Adrenergic signaling in cardiomyocytes	62/1047	205/7206	4.54661521036e-09
ko03040	Spliceosome	1/1047	145/7206	5.86554037857e-09
ko04720	Long-term potentiation	37/1047	99/7206	1.33083827766e-08
ko04970	Salivary secretion	36/1047	95/7206	1.36658202645e-08
ko05030	Cocaine addiction	29/1047	73/7206	1.06096075627e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1047	74/7206	5.80609623847e-07
ko05164	Influenza A	5/1047	167/7206	1.07454670769e-06
ko04060	Cytokine-cytokine receptor interaction	7/1047	191/7206	1.1217570118e-06
ko04972	Pancreatic secretion	36/1047	111/7206	1.70679202989e-06
ko04925	Aldosterone synthesis and secretion	34/1047	105/7206	3.69825859824e-06
ko03013	RNA transport	6/1047	166/7206	5.79122841226e-06
ko04971	Gastric acid secretion	31/1047	98/7206	1.52606143338e-05
ko05205	Proteoglycans in cancer	17/1047	271/7206	2.15775309979e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	26/1047	79/7206	3.13913040108e-05
ko05169	Epstein-Barr virus infection	11/1047	206/7206	3.31775753711e-05
ko05322	Systemic lupus erythematosus	6/1047	151/7206	3.45319087191e-05
ko04260	Cardiac muscle contraction	30/1047	98/7206	3.67234611024e-05
ko04976	Bile secretion	26/1047	80/7206	3.85634237698e-05
ko04514	Cell adhesion molecules (CAMs)	37/1047	130/7206	4.00040038886e-05
ko04120	Ubiquitin mediated proteolysis	5/1047	138/7206	4.28429568406e-05
ko05168	Herpes simplex infection	9/1047	182/7206	4.38114085893e-05
ko04621	NOD-like receptor signaling pathway	7/1047	157/7206	7.7704832437e-05
ko05162	Measles	4/1047	120/7206	0.000111023898955
ko04141	Protein processing in endoplasmic reticulum	10/1047	184/7206	0.000118250574516
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/1047	182/7206	0.000163475359704
ko04072	Phospholipase D signaling pathway	48/1047	197/7206	0.000197671635022
ko05166	HTLV-I infection	22/1047	292/7206	0.000250308345346
ko04110	Cell cycle	7/1047	145/7206	0.000297086352978
ko00310	Lysine degradation	1/1047	73/7206	0.000301579554235
ko04022	cGMP-PKG signaling pathway	51/1047	216/7206	0.000366931230577
ko04964	Proximal tubule bicarbonate reclamation	12/1047	29/7206	0.000393199077155
ko05161	Hepatitis B	10/1047	173/7206	0.000416981099483
ko04745	Phototransduction - fly	14/1047	38/7206	0.000545178037353
ko04966	Collecting duct acid secretion	11/1047	26/7206	0.000547295532475
ko04730	Long-term depression	23/1047	78/7206	0.000557213759798
ko05414	Dilated cardiomyopathy	30/1047	112/7206	0.000609835303903
ko03008	Ribosome biogenesis in eukaryotes	2/1047	79/7206	0.000631672891446
ko04540	Gap junction	33/1047	128/7206	0.000840070663076
ko05215	Prostate cancer	5/1047	111/7206	0.00101575454161
ko04924	Renin secretion	24/1047	86/7206	0.00105887116542
ko04630	Jak-STAT signaling pathway	7/1047	132/7206	0.00109008204992
ko04010	MAPK signaling pathway	67/1047	321/7206	0.00153014589371
ko03018	RNA degradation	3/1047	84/7206	0.00166650414852
ko05110	Vibrio cholerae infection	19/1047	63/7206	0.0016718105433
ko04064	NF-kappa B signaling pathway	4/1047	96/7206	0.0018953985077
ko04214	Apoptosis - fly	2/1047	72/7206	0.00202941334795
ko04750	Inflammatory mediator regulation of TRP channels	30/1047	122/7206	0.0027075934407
ko04070	Phosphatidylinositol signaling system	28/1047	112/7206	0.00279850399581
ko00520	Amino sugar and nucleotide sugar metabolism	1/1047	55/7206	0.00325764067238
ko05016	Huntington's disease	17/1047	215/7206	0.00415831820939
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1047	59/7206	0.00439330490699
ko04612	Antigen processing and presentation	3/1047	77/7206	0.0049965771591
ko04657	IL-17 signaling pathway	4/1047	87/7206	0.00530933218843
ko05410	Hypertrophic cardiomyopathy (HCM)	25/1047	100/7206	0.00592612958915
ko05140	Leishmaniasis	3/1047	75/7206	0.00734374989223
ko04218	Cellular senescence	14/1047	177/7206	0.00928443922647
ko03420	Nucleotide excision repair	1/1047	46/7206	0.0107141649854
ko05224	Breast cancer	14/1047	174/7206	0.0119485311966
ko04668	TNF signaling pathway	8/1047	120/7206	0.0123316961739
ko05321	Inflammatory bowel disease (IBD)	2/1047	56/7206	0.0130048377259
ko00240	Pyrimidine metabolism	7/1047	110/7206	0.0132433498244
ko04140	Autophagy - animal	13/1047	164/7206	0.0132810946389
ko04210	Apoptosis	15/1047	180/7206	0.0137327121526
ko04146	Peroxisome	5/1047	89/7206	0.0144200861338
ko05145	Toxoplasmosis	9/1047	126/7206	0.0149416804796
ko04510	Focal adhesion	22/1047	240/7206	0.0151585295087
ko03022	Basal transcription factors	1/1047	44/7206	0.0161676866279
ko05144	Malaria	1/1047	45/7206	0.0168451046753
ko00071	Fatty acid degradation	1/1047	45/7206	0.0168451046753
ko04915	Estrogen signaling pathway	29/1047	131/7206	0.0169751053836
ko04217	Necroptosis	15/1047	178/7206	0.0174767094339
ko05211	Renal cell carcinoma	6/1047	96/7206	0.0187020773166
ko04658	Th1 and Th2 cell differentiation	6/1047	96/7206	0.0187020773166
ko05220	Chronic myeloid leukemia	5/1047	85/7206	0.0195052017443
ko04640	Hematopoietic cell lineage	3/1047	64/7206	0.0199047031749
ko04115	p53 signaling pathway	4/1047	74/7206	0.0200292369777
ko04371	Apelin signaling pathway	37/1047	177/7206	0.0226040271535
ko04350	TGF-beta signaling pathway	7/1047	103/7206	0.0233815135686
ko05131	Shigellosis	5/1047	82/7206	0.0265923003771
ko05212	Pancreatic cancer	5/1047	83/7206	0.0268823144237
ko00590	Arachidonic acid metabolism	2/1047	52/7206	0.0274796025042
ko00330	Arginine and proline metabolism	3/1047	61/7206	0.0279929532553
ko04622	RIG-I-like receptor signaling pathway	3/1047	62/7206	0.0282246351742
ko05418	Fluid shear stress and atherosclerosis	15/1047	173/7206	0.0282284051378
ko05200	Pathways in cancer	55/1047	492/7206	0.0286299004058
ko00561	Glycerolipid metabolism	3/1047	63/7206	0.0288932099572
ko04620	Toll-like receptor signaling pathway	7/1047	100/7206	0.0310969660639
ko04923	Regulation of lipolysis in adipocytes	18/1047	77/7206	0.0337601827373
ko04341	Hedgehog signaling pathway - fly	1/1047	38/7206	0.035214917134
ko05217	Basal cell carcinoma	4/1047	68/7206	0.0380983062087
ko05206	MicroRNAs in cancer	16/1047	177/7206	0.0393662301019
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/1047	14/7206	0.041266786558
ko05133	Pertussis	6/1047	87/7206	0.0451921577151
ko00910	Nitrogen metabolism	6/1047	19/7206	0.0467340083951
ko01524	Platinum drug resistance	5/1047	76/7206	0.0487461815489
ko04810	Regulation of actin cytoskeleton	27/1047	264/7206	0.0496603588101
ko05012	Parkinson's disease	14/1047	155/7206	0.0499149304268