ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	149/715	423/7206	4.72176945086e-49
ko05033	Nicotine addiction	48/715	56/7206	1.05781589362e-40
ko04724	Glutamatergic synapse	73/715	152/7206	3.70289999963e-34
ko04727	GABAergic synapse	52/715	110/7206	3.9189257075e-24
ko05032	Morphine addiction	51/715	110/7206	3.36258141183e-23
ko04723	Retrograde endocannabinoid signaling	62/715	175/7206	1.86184045941e-20
ko04713	Circadian entrainment	53/715	136/7206	8.59881699687e-20
ko04728	Dopaminergic synapse	62/715	185/7206	4.82431201972e-19
ko04725	Cholinergic synapse	51/715	160/7206	7.80902236425e-15
ko04024	cAMP signaling pathway	71/715	279/7206	1.93536143911e-14
ko04721	Synaptic vesicle cycle	33/715	80/7206	1.31705494805e-13
ko04911	Insulin secretion	40/715	117/7206	5.2697115145e-13
ko04742	Taste transduction	27/715	61/7206	3.02376839505e-12
ko05031	Amphetamine addiction	33/715	91/7206	9.41915383809e-12
ko05030	Cocaine addiction	29/715	73/7206	1.26618371346e-11
ko04726	Serotonergic synapse	41/715	137/7206	3.5689099215e-11
ko04921	Oxytocin signaling pathway	53/715	209/7206	5.51954805834e-11
ko04720	Long-term potentiation	33/715	99/7206	1.29220490262e-10
ko04261	Adrenergic signaling in cardiomyocytes	51/715	205/7206	2.72603522595e-10
ko05014	Amyotrophic lateral sclerosis (ALS)	26/715	74/7206	3.4017494485e-09
ko04020	Calcium signaling pathway	58/715	265/7206	3.52315954851e-09
ko04010	MAPK signaling pathway	63/715	321/7206	8.41031314742e-08
ko04970	Salivary secretion	27/715	95/7206	2.72217717984e-07
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/715	79/7206	5.02294003589e-06
ko04060	Cytokine-cytokine receptor interaction	3/715	191/7206	6.25979177408e-06
ko04260	Cardiac muscle contraction	25/715	98/7206	6.52938426314e-06
ko04972	Pancreatic secretion	27/715	111/7206	7.40519444895e-06
ko03040	Spliceosome	1/715	145/7206	7.42430085066e-06
ko04730	Long-term depression	21/715	78/7206	1.45998326408e-05
ko04971	Gastric acid secretion	24/715	98/7206	2.09612479805e-05
ko04072	Phospholipase D signaling pathway	39/715	197/7206	2.7308801511e-05
ko05203	Viral carcinogenesis	9/715	277/7206	3.28025809559e-05
ko04925	Aldosterone synthesis and secretion	25/715	105/7206	3.96124508284e-05
ko03013	RNA transport	3/715	166/7206	5.83242343443e-05
ko04514	Cell adhesion molecules (CAMs)	28/715	130/7206	7.3380111656e-05
ko05168	Herpes simplex infection	4/715	182/7206	7.42822249248e-05
ko04360	Axon guidance	42/715	233/7206	0.000122058518813
ko04740	Olfactory transduction	19/715	80/7206	0.000230634172045
ko05414	Dilated cardiomyopathy	24/715	112/7206	0.000305634521684
ko05164	Influenza A	4/715	167/7206	0.000317505250375
ko04350	TGF-beta signaling pathway	1/715	103/7206	0.00038822187393
ko04961	Endocrine and other factor-regulated calcium reabsorption	15/715	59/7206	0.000475731559089
ko04120	Ubiquitin mediated proteolysis	3/715	138/7206	0.000755645142148
ko04540	Gap junction	25/715	128/7206	0.0008346833828
ko05322	Systemic lupus erythematosus	4/715	151/7206	0.000853508472524
ko04964	Proximal tubule bicarbonate reclamation	9/715	29/7206	0.00142922352511
ko04022	cGMP-PKG signaling pathway	36/715	216/7206	0.00165459003601
ko05410	Hypertrophic cardiomyopathy (HCM)	20/715	100/7206	0.00199557725224
ko03018	RNA degradation	1/715	84/7206	0.00274974349057
ko04915	Estrogen signaling pathway	24/715	131/7206	0.00278332779123
ko05162	Measles	3/715	120/7206	0.00302141329002
ko04932	Non-alcoholic fatty liver disease (NAFLD)	7/715	182/7206	0.00353106829372
ko03008	Ribosome biogenesis in eukaryotes	1/715	79/7206	0.00402211549397
ko05169	Epstein-Barr virus infection	9/715	206/7206	0.00433706805055
ko04110	Cell cycle	5/715	145/7206	0.0047769653725
ko04924	Renin secretion	17/715	86/7206	0.00535471467357
ko05034	Alcoholism	37/715	238/7206	0.00550484848005
ko04014	Ras signaling pathway	42/715	279/7206	0.00556534606648
ko00240	Pyrimidine metabolism	3/715	110/7206	0.00599218024864
ko04612	Antigen processing and presentation	1/715	77/7206	0.00608105059339
ko01200	Carbon metabolism	4/715	128/7206	0.00652379213021
ko04973	Carbohydrate digestion and absorption	10/715	42/7206	0.00675985576541
ko05231	Choline metabolism in cancer	23/715	134/7206	0.00805153618913
ko00310	Lysine degradation	1/715	73/7206	0.00893939920082
ko04930	Type II diabetes mellitus	12/715	54/7206	0.00915984815652
ko05205	Proteoglycans in cancer	15/715	271/7206	0.0124799551232
ko04750	Inflammatory mediator regulation of TRP channels	21/715	122/7206	0.0132044100734
ko04976	Bile secretion	15/715	80/7206	0.0133326100793
ko04960	Aldosterone-regulated sodium reabsorption	9/715	41/7206	0.0170169417812
ko04150	mTOR signaling pathway	9/715	184/7206	0.0172575497014
ko04330	Notch signaling pathway	1/715	62/7206	0.01863436331
ko04621	NOD-like receptor signaling pathway	7/715	157/7206	0.0205894481591
ko04666	Fc gamma R-mediated phagocytosis	20/715	122/7206	0.0213916518906
ko04744	Phototransduction	8/715	36/7206	0.0222390748083
ko04071	Sphingolipid signaling pathway	25/715	162/7206	0.0232210061971
ko04015	Rap1 signaling pathway	39/715	278/7206	0.0240429805489
ko04140	Autophagy - animal	8/715	164/7206	0.0245303779428
ko04142	Lysosome	7/715	151/7206	0.0267301358137
ko00010	Glycolysis / Gluconeogenesis	2/715	74/7206	0.030837567221
ko05140	Leishmaniasis	2/715	75/7206	0.0309918584243
ko00280	Valine, leucine and isoleucine degradation	1/715	54/7206	0.0395964148624
ko05321	Inflammatory bowel disease (IBD)	1/715	56/7206	0.0401915643004
ko00604	Glycosphingolipid biosynthesis - ganglio series	4/715	14/7206	0.0428925681507
ko01230	Biosynthesis of amino acids	3/715	85/7206	0.0441338918622
ko04141	Protein processing in endoplasmic reticulum	10/715	184/7206	0.0443041166301
ko04214	Apoptosis - fly	2/715	72/7206	0.0444904621723
ko05166	HTLV-I infection	19/715	292/7206	0.0454989533589
ko04068	FoxO signaling pathway	9/715	167/7206	0.0486519979416
ko04745	Phototransduction - fly	8/715	38/7206	0.0488169773599