ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	137/905	423/7206	1.77377254103e-28
ko05033	Nicotine addiction	40/905	56/7206	2.36576222786e-24
ko04724	Glutamatergic synapse	66/905	152/7206	9.69381568948e-22
ko04744	Phototransduction	26/905	36/7206	1.97470463124e-16
ko05032	Morphine addiction	48/905	110/7206	3.22721594554e-16
ko04727	GABAergic synapse	47/905	110/7206	1.80233194312e-15
ko04723	Retrograde endocannabinoid signaling	60/905	175/7206	4.25591636238e-14
ko04713	Circadian entrainment	51/905	136/7206	6.46762145331e-14
ko04725	Cholinergic synapse	55/905	160/7206	4.49374847816e-13
ko04721	Synaptic vesicle cycle	36/905	80/7206	5.68100031816e-13
ko04728	Dopaminergic synapse	58/905	185/7206	8.3398307744e-12
ko04726	Serotonergic synapse	46/905	137/7206	9.68888723417e-11
ko04972	Pancreatic secretion	38/905	111/7206	2.27937764226e-09
ko04024	cAMP signaling pathway	71/905	279/7206	2.89252845179e-09
ko04911	Insulin secretion	39/905	117/7206	3.35818936942e-09
ko04742	Taste transduction	26/905	61/7206	4.13425874897e-09
ko04020	Calcium signaling pathway	66/905	265/7206	2.23045759101e-08
ko04976	Bile secretion	29/905	80/7206	4.33412631817e-08
ko04978	Mineral absorption	18/905	40/7206	3.86175865253e-07
ko04740	Olfactory transduction	27/905	80/7206	6.7098452589e-07
ko04970	Salivary secretion	30/905	95/7206	8.27147841064e-07
ko05031	Amphetamine addiction	29/905	91/7206	1.01917626912e-06
ko03040	Spliceosome	2/905	145/7206	1.43580163326e-06
ko04921	Oxytocin signaling pathway	51/905	209/7206	2.01043470279e-06
ko05203	Viral carcinogenesis	12/905	277/7206	3.04579710189e-06
ko04120	Ubiquitin mediated proteolysis	2/905	138/7206	3.12540168899e-06
ko05166	HTLV-I infection	13/905	292/7206	3.2043750615e-06
ko03013	RNA transport	4/905	166/7206	4.52766888979e-06
ko05030	Cocaine addiction	24/905	73/7206	4.71420846966e-06
ko04974	Protein digestion and absorption	28/905	96/7206	1.30196135651e-05
ko04971	Gastric acid secretion	28/905	98/7206	1.81796139493e-05
ko04514	Cell adhesion molecules (CAMs)	34/905	130/7206	2.17832989178e-05
ko05322	Systemic lupus erythematosus	4/905	151/7206	2.95122049422e-05
ko04060	Cytokine-cytokine receptor interaction	7/905	191/7206	3.25856782491e-05
ko04110	Cell cycle	4/905	145/7206	6.24353240375e-05
ko05164	Influenza A	6/905	167/7206	8.18559371551e-05
ko04964	Proximal tubule bicarbonate reclamation	12/905	29/7206	9.58737202391e-05
ko05169	Epstein-Barr virus infection	9/905	206/7206	0.000100331776289
ko04550	Signaling pathways regulating pluripotency of stem cells	6/905	165/7206	0.000115576938242
ko05162	Measles	3/905	120/7206	0.00014425170982
ko04261	Adrenergic signaling in cardiomyocytes	45/905	205/7206	0.000150526913141
ko04260	Cardiac muscle contraction	26/905	98/7206	0.000155659705349
ko02010	ABC transporters	14/905	39/7206	0.000158619587315
ko04621	NOD-like receptor signaling pathway	6/905	157/7206	0.000227531670604
ko05014	Amyotrophic lateral sclerosis (ALS)	21/905	74/7206	0.000250400606412
ko04217	Necroptosis	8/905	178/7206	0.000345883589906
ko05205	Proteoglycans in cancer	16/905	271/7206	0.000350641130179
ko04720	Long-term potentiation	25/905	99/7206	0.000577741343622
ko05161	Hepatitis B	8/905	173/7206	0.000659887863205
ko04924	Renin secretion	22/905	86/7206	0.000838580197742
ko05200	Pathways in cancer	39/905	492/7206	0.000894032802337
ko05168	Herpes simplex infection	9/905	182/7206	0.000897304832554
ko04350	TGF-beta signaling pathway	3/905	103/7206	0.00135044485787
ko04973	Carbohydrate digestion and absorption	13/905	42/7206	0.00136256573417
ko04730	Long-term depression	20/905	78/7206	0.00152398393313
ko04022	cGMP-PKG signaling pathway	43/905	216/7206	0.00168566136103
ko04150	mTOR signaling pathway	10/905	184/7206	0.0021268661153
ko04141	Protein processing in endoplasmic reticulum	10/905	184/7206	0.0021268661153
ko04966	Collecting duct acid secretion	9/905	26/7206	0.00317972241138
ko04630	Jak-STAT signaling pathway	6/905	132/7206	0.00318198642523
ko04010	MAPK signaling pathway	58/905	321/7206	0.00333485701797
ko04218	Cellular senescence	10/905	177/7206	0.00376963453593
ko00830	Retinol metabolism	12/905	42/7206	0.0043324824597
ko04614	Renin-angiotensin system	7/905	18/7206	0.00436691428391
ko05016	Huntington's disease	14/905	215/7206	0.00463448219566
ko04745	Phototransduction - fly	11/905	38/7206	0.00556829423844
ko05215	Prostate cancer	5/905	111/7206	0.00591403118143
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/905	182/7206	0.00612799686578
ko00290	Valine, leucine and isoleucine biosynthesis	3/905	4/7206	0.00715862696207
ko05202	Transcriptional misregulation in cancer	12/905	188/7206	0.00720904690193
ko04510	Focal adhesion	17/905	240/7206	0.00728368311025
ko03018	RNA degradation	3/905	84/7206	0.00760616802542
ko05220	Chronic myeloid leukemia	3/905	85/7206	0.00765661576746
ko05206	MicroRNAs in cancer	11/905	177/7206	0.00788515735729
ko04064	NF-kappa B signaling pathway	4/905	96/7206	0.00803061284183
ko04975	Fat digestion and absorption	10/905	35/7206	0.00891163619072
ko05217	Basal cell carcinoma	2/905	68/7206	0.00973000728552
ko05224	Breast cancer	11/905	174/7206	0.0103439933958
ko03015	mRNA surveillance pathway	4/905	93/7206	0.0111702400757
ko04011	MAPK signaling pathway - yeast	1/905	53/7206	0.0115634877564
ko04210	Apoptosis	12/905	180/7206	0.0121574545022
ko04960	Aldosterone-regulated sodium reabsorption	11/905	41/7206	0.0142951441145
ko04612	Antigen processing and presentation	3/905	77/7206	0.0151409619556
ko04961	Endocrine and other factor-regulated calcium reabsorption	14/905	59/7206	0.0160498896224
ko04925	Aldosterone synthesis and secretion	22/905	105/7206	0.016290944175
ko04710	Circadian rhythm	11/905	43/7206	0.0178841596172
ko04390	Hippo signaling pathway	13/905	188/7206	0.0184659189498
ko04930	Type II diabetes mellitus	13/905	54/7206	0.0203044233755
ko04072	Phospholipase D signaling pathway	36/905	197/7206	0.021311775303
ko04657	IL-17 signaling pathway	4/905	87/7206	0.0214863288594
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/905	79/7206	0.0245616867342
ko04668	TNF signaling pathway	7/905	120/7206	0.0250612606671
ko03420	Nucleotide excision repair	1/905	46/7206	0.0251290847435
ko05219	Bladder cancer	1/905	48/7206	0.0258276269379
ko00380	Tryptophan metabolism	12/905	50/7206	0.0283266483958
ko05211	Renal cell carcinoma	5/905	96/7206	0.028508868498
ko00350	Tyrosine metabolism	9/905	33/7206	0.0293181654499
ko04113	Meiosis - yeast	3/905	70/7206	0.0297276446195
ko00340	Histidine metabolism	7/905	25/7206	0.030128936959
ko00120	Primary bile acid biosynthesis	6/905	20/7206	0.0316166632737
ko05110	Vibrio cholerae infection	14/905	63/7206	0.0326811623553
ko04914	Progesterone-mediated oocyte maturation	6/905	104/7206	0.0356808009022
ko04810	Regulation of actin cytoskeleton	22/905	264/7206	0.036811416279
ko03022	Basal transcription factors	1/905	44/7206	0.0372822743754
ko05144	Malaria	1/905	45/7206	0.0382678234601
ko05321	Inflammatory bowel disease (IBD)	2/905	56/7206	0.0409883516983
ko04611	Platelet activation	12/905	163/7206	0.0418290809206
ko04140	Autophagy - animal	12/905	164/7206	0.0419610555008
ko04142	Lysosome	11/905	151/7206	0.0469398124802