ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/957	423/7206	5.81748974006e-46
ko04724	Glutamatergic synapse	88/957	152/7206	2.74131304361e-39
ko05033	Nicotine addiction	50/957	56/7206	6.83532494206e-38
ko05032	Morphine addiction	65/957	110/7206	6.36911115729e-30
ko04727	GABAergic synapse	63/957	110/7206	5.95871891096e-28
ko04713	Circadian entrainment	70/957	136/7206	4.32042323214e-27
ko04728	Dopaminergic synapse	80/957	185/7206	2.24894049195e-24
ko04723	Retrograde endocannabinoid signaling	76/957	175/7206	2.4480639756e-23
ko04725	Cholinergic synapse	70/957	160/7206	8.60916176473e-22
ko04024	cAMP signaling pathway	94/957	279/7206	3.32259337897e-19
ko04721	Synaptic vesicle cycle	44/957	80/7206	6.58582843256e-19
ko04911	Insulin secretion	54/957	117/7206	2.42846977874e-18
ko04726	Serotonergic synapse	56/957	137/7206	4.99882657555e-16
ko04742	Taste transduction	33/957	61/7206	3.26711048894e-14
ko04921	Oxytocin signaling pathway	69/957	209/7206	7.5222278242e-14
ko05031	Amphetamine addiction	41/957	91/7206	8.89963031267e-14
ko04020	Calcium signaling pathway	80/957	265/7206	1.98751056785e-13
ko04720	Long-term potentiation	42/957	99/7206	5.52000629595e-13
ko04261	Adrenergic signaling in cardiomyocytes	65/957	205/7206	3.43025717108e-12
ko05030	Cocaine addiction	33/957	73/7206	2.165726157e-11
ko04744	Phototransduction	21/957	36/7206	2.43249903193e-10
ko04970	Salivary secretion	37/957	95/7206	2.71033386629e-10
ko04971	Gastric acid secretion	37/957	98/7206	7.67263521786e-10
ko04925	Aldosterone synthesis and secretion	38/957	105/7206	1.8570737358e-09
ko04060	Cytokine-cytokine receptor interaction	3/957	191/7206	8.04498534703e-09
ko03040	Spliceosome	1/957	145/7206	3.64298333948e-08
ko04010	MAPK signaling pathway	78/957	321/7206	4.6000442509e-08
ko05203	Viral carcinogenesis	10/957	277/7206	5.90167160282e-08
ko04972	Pancreatic secretion	36/957	111/7206	1.30503839834e-07
ko05168	Herpes simplex infection	4/957	182/7206	1.98675549558e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	27/957	74/7206	3.45794425644e-07
ko04072	Phospholipase D signaling pathway	49/957	197/7206	9.03984539218e-06
ko04350	TGF-beta signaling pathway	1/957	103/7206	1.21650867252e-05
ko04260	Cardiac muscle contraction	29/957	98/7206	1.71710567298e-05
ko04022	cGMP-PKG signaling pathway	51/957	216/7206	2.48195504677e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/957	79/7206	2.96241848976e-05
ko04740	Olfactory transduction	25/957	80/7206	3.28133889133e-05
ko04915	Estrogen signaling pathway	35/957	131/7206	3.74026234906e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/957	59/7206	3.98771190719e-05
ko05164	Influenza A	6/957	167/7206	3.99047781108e-05
ko05322	Systemic lupus erythematosus	5/957	151/7206	4.786660662e-05
ko05414	Dilated cardiomyopathy	31/957	112/7206	5.39123649447e-05
ko04730	Long-term depression	24/957	78/7206	5.70957401471e-05
ko04514	Cell adhesion molecules (CAMs)	34/957	130/7206	6.79117991952e-05
ko04621	NOD-like receptor signaling pathway	6/957	157/7206	0.000111251367146
ko03013	RNA transport	7/957	166/7206	0.000171550057217
ko04120	Ubiquitin mediated proteolysis	5/957	138/7206	0.000196022245503
ko05169	Epstein-Barr virus infection	11/957	206/7206	0.000238686374083
ko04141	Protein processing in endoplasmic reticulum	9/957	184/7206	0.000243571909291
ko04360	Axon guidance	51/957	233/7206	0.000246539440667
ko04540	Gap junction	32/957	128/7206	0.000307408650681
ko04070	Phosphatidylinositol signaling system	29/957	112/7206	0.000338920093762
ko04110	Cell cycle	6/957	145/7206	0.000441807499034
ko04612	Antigen processing and presentation	1/957	77/7206	0.000503605982026
ko04976	Bile secretion	22/957	80/7206	0.00067046983437
ko04745	Phototransduction - fly	13/957	38/7206	0.00080534886465
ko00240	Pyrimidine metabolism	4/957	110/7206	0.00100022797091
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/957	14/7206	0.00104519720943
ko05162	Measles	5/957	120/7206	0.00155964954635
ko04912	GnRH signaling pathway	29/957	122/7206	0.00167704704552
ko04750	Inflammatory mediator regulation of TRP channels	29/957	122/7206	0.00167704704552
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	7/957	15/7206	0.00173677862139
ko04924	Renin secretion	22/957	86/7206	0.00196857449812
ko03008	Ribosome biogenesis in eukaryotes	2/957	79/7206	0.0021940460941
ko04371	Apelin signaling pathway	38/957	177/7206	0.00227183931982
ko04640	Hematopoietic cell lineage	1/957	64/7206	0.00239358235922
ko05205	Proteoglycans in cancer	20/957	271/7206	0.00249207576847
ko04932	Non-alcoholic fatty liver disease (NAFLD)	11/957	182/7206	0.00258188310414
ko04014	Ras signaling pathway	54/957	279/7206	0.00380883440717
ko05110	Vibrio cholerae infection	17/957	63/7206	0.00405202835199
ko04630	Jak-STAT signaling pathway	7/957	132/7206	0.00410390192415
ko05161	Hepatitis B	11/957	173/7206	0.0044200851489
ko05034	Alcoholism	47/957	238/7206	0.00462031077429
ko04966	Collecting duct acid secretion	9/957	26/7206	0.00466524018735
ko04140	Autophagy - animal	10/957	164/7206	0.00483807737083
ko05321	Inflammatory bowel disease (IBD)	1/957	56/7206	0.00511259252687
ko03018	RNA degradation	3/957	84/7206	0.00527145048445
ko04918	Thyroid hormone synthesis	21/957	86/7206	0.00566743434264
ko04064	NF-kappa B signaling pathway	4/957	96/7206	0.00571514626664
ko05410	Hypertrophic cardiomyopathy (HCM)	23/957	100/7206	0.00696673678223
ko04217	Necroptosis	12/957	178/7206	0.00701764678576
ko05145	Toxoplasmosis	7/957	126/7206	0.00756474777009
ko04015	Rap1 signaling pathway	52/957	278/7206	0.00878822521238
ko00513	Various types of N-glycan biosynthesis	12/957	42/7206	0.00929721445322
ko00512	Mucin type O-glycan biosynthesis	9/957	29/7206	0.0103526535884
ko04964	Proximal tubule bicarbonate reclamation	9/957	29/7206	0.0103526535884
ko01524	Platinum drug resistance	3/957	76/7206	0.0104604087247
ko05222	Small cell lung cancer	4/957	89/7206	0.0109836244977
ko00515	Mannose type O-glycan biosynthesis	8/957	25/7206	0.0126473583492
ko04210	Apoptosis	13/957	180/7206	0.0139075859089
ko04062	Chemokine signaling pathway	39/957	201/7206	0.014747650547
ko00310	Lysine degradation	3/957	73/7206	0.0147548227147
ko05140	Leishmaniasis	3/957	75/7206	0.0151303423167
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	8/957	26/7206	0.0161949664213
ko04923	Regulation of lipolysis in adipocytes	18/957	77/7206	0.0163549187525
ko00260	Glycine, serine and threonine metabolism	1/957	48/7206	0.0168653034896
ko04550	Signaling pathways regulating pluripotency of stem cells	12/957	165/7206	0.0197741064376
ko04973	Carbohydrate digestion and absorption	11/957	42/7206	0.0208601977705
ko04214	Apoptosis - fly	3/957	72/7206	0.0213700811983
ko05418	Fluid shear stress and atherosclerosis	13/957	173/7206	0.0227564031362
ko00071	Fatty acid degradation	1/957	45/7206	0.0249566904101
ko03420	Nucleotide excision repair	1/957	46/7206	0.0258358968885
ko04930	Type II diabetes mellitus	13/957	54/7206	0.0259851693091
ko04146	Peroxisome	5/957	89/7206	0.0275917278892
ko00480	Glutathione metabolism	2/957	55/7206	0.0280276335734
ko04670	Leukocyte transendothelial migration	11/957	151/7206	0.0283551454514
ko05202	Transcriptional misregulation in cancer	15/957	188/7206	0.028983439502
ko04270	Vascular smooth muscle contraction	30/957	154/7206	0.0297854608404
ko05016	Huntington's disease	18/957	215/7206	0.0316395311836
ko05215	Prostate cancer	7/957	111/7206	0.0329576261101
ko00510	N-Glycan biosynthesis	12/957	50/7206	0.0344702743709
ko01200	Carbon metabolism	9/957	128/7206	0.0348283617577
ko04657	IL-17 signaling pathway	5/957	87/7206	0.0375059427148
ko05231	Choline metabolism in cancer	26/957	134/7206	0.0397462158003
ko04114	Oocyte meiosis	27/957	139/7206	0.0421646052196
ko05166	HTLV-I infection	27/957	292/7206	0.0423223113274
ko04916	Melanogenesis	27/957	142/7206	0.0459119563591