ko pathway ratio_in_study ratio_in_pop p_value ko04380 Osteoclast differentiation 33/329 134/7206 4.55996204943e-16 ko04621 NOD-like receptor signaling pathway 34/329 157/7206 1.03031797736e-14 ko04060 Cytokine-cytokine receptor interaction 36/329 191/7206 1.51310336637e-13 ko04668 TNF signaling pathway 27/329 120/7206 2.50119673006e-12 ko04064 NF-kappa B signaling pathway 22/329 96/7206 1.9666529637e-10 ko05164 Influenza A 29/329 167/7206 3.18077870196e-10 ko05168 Herpes simplex infection 29/329 182/7206 2.58190994277e-09 ko04620 Toll-like receptor signaling pathway 21/329 100/7206 2.84220737423e-09 ko04657 IL-17 signaling pathway 19/329 87/7206 8.29474966451e-09 ko05161 Hepatitis B 27/329 173/7206 1.48654975402e-08 ko04217 Necroptosis 27/329 178/7206 2.77349464011e-08 ko05133 Pertussis 17/329 87/7206 2.88305672534e-07 ko04622 RIG-I-like receptor signaling pathway 14/329 62/7206 5.15014228051e-07 ko05140 Leishmaniasis 15/329 75/7206 1.06840678999e-06 ko04623 Cytosolic DNA-sensing pathway 11/329 41/7206 1.40182055072e-06 ko04933 AGE-RAGE signaling pathway in diabetic complications 20/329 135/7206 2.70710675556e-06 ko05145 Toxoplasmosis 19/329 126/7206 3.69081055648e-06 ko05162 Measles 18/329 120/7206 7.20081794895e-06 ko04630 Jak-STAT signaling pathway 19/329 132/7206 7.44191763871e-06 ko05323 Rheumatoid arthritis 15/329 89/7206 9.98820484621e-06 ko04660 T cell receptor signaling pathway 18/329 124/7206 1.15061812183e-05 ko05152 Tuberculosis 23/329 187/7206 1.23017528738e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 23/329 191/7206 1.74571431113e-05 ko05160 Hepatitis C 20/329 153/7206 1.86952140958e-05 ko04210 Apoptosis 22/329 180/7206 2.10856974721e-05 ko04658 Th1 and Th2 cell differentiation 15/329 96/7206 2.55962696826e-05 ko04672 Intestinal immune network for IgA production 9/329 37/7206 3.09146016784e-05 ko05132 Salmonella infection 15/329 98/7206 3.29010482526e-05 ko05321 Inflammatory bowel disease (IBD) 11/329 56/7206 3.56966305177e-05 ko05134 Legionellosis 12/329 74/7206 0.000114413662148 ko04662 B cell receptor signaling pathway 13/329 88/7206 0.000159585003666 ko05142 Chagas disease (American trypanosomiasis) 16/329 130/7206 0.000261552583994 ko04659 Th17 cell differentiation 14/329 106/7206 0.000302383867544 ko05131 Shigellosis 12/329 82/7206 0.000311096934462 ko04062 Chemokine signaling pathway 21/329 201/7206 0.000386210466578 ko04610 Complement and coagulation cascades 11/329 79/7206 0.000847130617129 ko05150 Staphylococcus aureus infection 7/329 36/7206 0.00102969591654 ko04080 Neuroactive ligand-receptor interaction 7/329 423/7206 0.00160780606898 ko04115 p53 signaling pathway 10/329 74/7206 0.00182348688776 ko05340 Primary immunodeficiency 6/329 30/7206 0.00202572198022 ko04670 Leukocyte transendothelial migration 16/329 151/7206 0.00218021779929 ko05034 Alcoholism 2/329 238/7206 0.0022148381531 ko05120 Epithelial cell signaling in Helicobacter pylori infection 11/329 92/7206 0.00297281713267 ko04650 Natural killer cell mediated cytotoxicity 11/329 97/7206 0.00449377669429 ko05146 Amoebiasis 11/329 99/7206 0.00525267576355 ko04624 Toll and Imd signaling pathway 7/329 49/7206 0.00637806211856 ko05202 Transcriptional misregulation in cancer 17/329 188/7206 0.00672616365456 ko04550 Signaling pathways regulating pluripotency of stem cells 1/329 165/7206 0.00715658676164 ko04612 Antigen processing and presentation 9/329 77/7206 0.00806286701949 ko05418 Fluid shear stress and atherosclerosis 16/329 173/7206 0.00811527049379 ko04512 ECM-receptor interaction 9/329 79/7206 0.0095018342448 ko05200 Pathways in cancer 35/329 492/7206 0.00950784213266 ko05012 Parkinson's disease 1/329 155/7206 0.0103068883613 ko00051 Fructose and mannose metabolism 6/329 42/7206 0.0113091005584 ko00643 Styrene degradation 2/329 4/7206 0.0117288106226 ko04666 Fc gamma R-mediated phagocytosis 12/329 122/7206 0.0127321130921 ko05144 Malaria 6/329 45/7206 0.0156692303583 ko04724 Glutamatergic synapse 1/329 152/7206 0.0158225989243 ko05169 Epstein-Barr virus infection 17/329 206/7206 0.0164148446619 ko04917 Prolactin signaling pathway 9/329 87/7206 0.0172569461918 ko04728 Dopaminergic synapse 2/329 185/7206 0.0182523366972 ko05016 Huntington's disease 3/329 215/7206 0.0189516032943 ko04215 Apoptosis - multiple species 6/329 47/7206 0.0191500516942 ko04114 Oocyte meiosis 1/329 139/7206 0.0217450259149 ko04932 Non-alcoholic fatty liver disease (NAFLD) 15/329 182/7206 0.0279879788166 ko04010 MAPK signaling pathway 23/329 321/7206 0.0281222099913 ko01522 Endocrine resistance 11/329 124/7206 0.0287092967158 ko00190 Oxidative phosphorylation 1/329 127/7206 0.0309498287691 ko01200 Carbon metabolism 1/329 128/7206 0.031003556637 ko05416 Viral myocarditis 6/329 55/7206 0.0382531290293 ko05320 Autoimmune thyroid disease 4/329 29/7206 0.0411576098731 ko05166 HTLV-I infection 21/329 292/7206 0.0430326804675