ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04724	Glutamatergic synapse	68/686	152/7206	1.33462060109e-30
ko05033	Nicotine addiction	40/686	56/7206	4.65849385535e-29
ko05032	Morphine addiction	54/686	110/7206	5.9414989818e-27
ko04727	GABAergic synapse	53/686	110/7206	5.77228988201e-26
ko04728	Dopaminergic synapse	65/686	185/7206	3.55260944073e-22
ko04723	Retrograde endocannabinoid signaling	63/686	175/7206	3.62499114485e-22
ko04080	Neuroactive ligand-receptor interaction	101/686	423/7206	2.89147555966e-19
ko04713	Circadian entrainment	51/686	136/7206	5.083218429e-19
ko04721	Synaptic vesicle cycle	38/686	80/7206	1.20551304604e-18
ko04725	Cholinergic synapse	52/686	160/7206	2.89845287431e-16
ko04744	Phototransduction	22/686	36/7206	2.58688482509e-14
ko04024	cAMP signaling pathway	68/686	279/7206	8.930274533e-14
ko04911	Insulin secretion	38/686	117/7206	3.41913342537e-12
ko04726	Serotonergic synapse	38/686	137/7206	6.48455369714e-10
ko04921	Oxytocin signaling pathway	48/686	209/7206	4.62804604384e-09
ko04261	Adrenergic signaling in cardiomyocytes	47/686	205/7206	7.14909050779e-09
ko05030	Cocaine addiction	24/686	73/7206	2.69771707095e-08
ko05031	Amphetamine addiction	27/686	91/7206	4.30928954608e-08
ko04020	Calcium signaling pathway	54/686	265/7206	4.51426588804e-08
ko04010	MAPK signaling pathway	62/686	321/7206	4.54541859558e-08
ko04720	Long-term potentiation	28/686	99/7206	7.59865320562e-08
ko04742	Taste transduction	21/686	61/7206	8.15282828195e-08
ko05203	Viral carcinogenesis	5/686	277/7206	3.0262969621e-07
ko04072	Phospholipase D signaling pathway	41/686	197/7206	1.47555266687e-06
ko03040	Spliceosome	1/686	145/7206	1.12665691037e-05
ko04925	Aldosterone synthesis and secretion	25/686	105/7206	1.16478910051e-05
ko04060	Cytokine-cytokine receptor interaction	3/686	191/7206	1.38996745238e-05
ko04514	Cell adhesion molecules (CAMs)	28/686	130/7206	2.84905625402e-05
ko04970	Salivary secretion	22/686	95/7206	6.09198416633e-05
ko05169	Epstein-Barr virus infection	5/686	206/7206	9.03807480109e-05
ko04740	Olfactory transduction	19/686	80/7206	0.000133795704183
ko04730	Long-term depression	18/686	78/7206	0.000293302437122
ko04260	Cardiac muscle contraction	21/686	98/7206	0.00033684816509
ko04966	Collecting duct acid secretion	9/686	26/7206	0.000429974713909
ko05164	Influenza A	4/686	167/7206	0.000438457782708
ko04070	Phosphatidylinositol signaling system	23/686	112/7206	0.000450501979459
ko04141	Protein processing in endoplasmic reticulum	5/686	184/7206	0.000496448681769
ko04110	Cell cycle	3/686	145/7206	0.000524202489785
ko04972	Pancreatic secretion	22/686	111/7206	0.000827863798737
ko04621	NOD-like receptor signaling pathway	4/686	157/7206	0.000871972387902
ko04120	Ubiquitin mediated proteolysis	3/686	138/7206	0.0010737684459
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/686	14/7206	0.00112027432631
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/686	79/7206	0.00135909595143
ko04022	cGMP-PKG signaling pathway	35/686	216/7206	0.00140754467941
ko04915	Estrogen signaling pathway	24/686	131/7206	0.00142335983472
ko04014	Ras signaling pathway	43/686	279/7206	0.00164084021165
ko05322	Systemic lupus erythematosus	4/686	151/7206	0.00175591180707
ko03013	RNA transport	5/686	166/7206	0.00185798213124
ko05110	Vibrio cholerae infection	14/686	63/7206	0.00198609754999
ko05162	Measles	3/686	120/7206	0.00432253003243
ko05034	Alcoholism	36/686	238/7206	0.00471224939048
ko05414	Dilated cardiomyopathy	20/686	112/7206	0.0051531928696
ko04971	Gastric acid secretion	18/686	98/7206	0.00523965291918
ko04144	Endocytosis	48/686	342/7206	0.00591477032363
ko03008	Ribosome biogenesis in eukaryotes	1/686	79/7206	0.00604453829387
ko04360	Axon guidance	35/686	233/7206	0.00611178649063
ko04371	Apelin signaling pathway	28/686	177/7206	0.00622412743686
ko04630	Jak-STAT signaling pathway	4/686	132/7206	0.00652099086739
ko05168	Herpes simplex infection	7/686	182/7206	0.00663072429913
ko04062	Chemokine signaling pathway	31/686	201/7206	0.00683286203603
ko04064	NF-kappa B signaling pathway	2/686	96/7206	0.0076850977233
ko05215	Prostate cancer	3/686	111/7206	0.00855208144814
ko04612	Antigen processing and presentation	1/686	77/7206	0.00932849354587
ko00562	Inositol phosphate metabolism	16/686	89/7206	0.0104436824158
ko05205	Proteoglycans in cancer	14/686	271/7206	0.0109481799102
ko04510	Focal adhesion	12/686	240/7206	0.0133576909798
ko00310	Lysine degradation	1/686	73/7206	0.0137537986761
ko05014	Amyotrophic lateral sclerosis (ALS)	14/686	74/7206	0.0143103135054
ko04964	Proximal tubule bicarbonate reclamation	7/686	29/7206	0.0166706630433
ko04350	TGF-beta signaling pathway	3/686	103/7206	0.0168060387883
ko04140	Autophagy - animal	7/686	164/7206	0.0209230145596
ko04540	Gap junction	20/686	128/7206	0.0224965401701
ko03018	RNA degradation	2/686	84/7206	0.0225890648268
ko05231	Choline metabolism in cancer	21/686	134/7206	0.0241697395274
ko04745	Phototransduction - fly	8/686	38/7206	0.0241917284682
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/686	59/7206	0.0244035856144
ko05161	Hepatitis B	8/686	173/7206	0.0249141822806
ko04666	Fc gamma R-mediated phagocytosis	19/686	122/7206	0.028447734523
ko04640	Hematopoietic cell lineage	1/686	64/7206	0.0287848823568
ko04932	Non-alcoholic fatty liver disease (NAFLD)	9/686	182/7206	0.0294691936427
ko05120	Epithelial cell signaling in Helicobacter pylori infection	15/686	92/7206	0.0318070710145
ko04930	Type II diabetes mellitus	10/686	54/7206	0.0335952951939
ko04670	Leukocyte transendothelial migration	7/686	151/7206	0.0352875466244
ko05410	Hypertrophic cardiomyopathy (HCM)	16/686	100/7206	0.0372108205338
ko05321	Inflammatory bowel disease (IBD)	1/686	56/7206	0.0400382253229
ko04918	Thyroid hormone synthesis	14/686	86/7206	0.0404936000315
ko04214	Apoptosis - fly	2/686	72/7206	0.0440430213778
ko05222	Small cell lung cancer	3/686	89/7206	0.0445906993127
ko05140	Leishmaniasis	2/686	75/7206	0.0448865153223
ko01524	Platinum drug resistance	2/686	76/7206	0.0457721032081
ko05418	Fluid shear stress and atherosclerosis	9/686	173/7206	0.0489379716102