ko pathway ratio_in_study ratio_in_pop p_value ko04020 Calcium signaling pathway 5/13 265/7206 6.54046837973e-05 ko04540 Gap junction 3/13 128/7206 0.00137452354006 ko05032 Morphine addiction 2/13 110/7206 0.0161391638616 ko04070 Phosphatidylinositol signaling system 2/13 112/7206 0.016700166592 ko04750 Inflammatory mediator regulation of TRP channels 2/13 122/7206 0.019629787341 ko04725 Cholinergic synapse 2/13 160/7206 0.0325495288364 ko04080 Neuroactive ligand-receptor interaction 3/13 423/7206 0.0369741361597 ko00230 Purine metabolism 2/13 194/7206 0.0462833393403 ko04072 Phospholipase D signaling pathway 2/13 197/7206 0.047584844263