ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04721	Synaptic vesicle cycle	35/432	80/7206	2.10389927922e-22
ko04080	Neuroactive ligand-receptor interaction	80/432	423/7206	1.51798048678e-21
ko04724	Glutamatergic synapse	45/432	152/7206	2.76234185198e-20
ko05033	Nicotine addiction	26/432	56/7206	1.00305494793e-17
ko04727	GABAergic synapse	35/432	110/7206	4.24348881042e-17
ko04728	Dopaminergic synapse	44/432	185/7206	7.06766498744e-16
ko04723	Retrograde endocannabinoid signaling	42/432	175/7206	2.38433290092e-15
ko05032	Morphine addiction	33/432	110/7206	2.46996042737e-15
ko04713	Circadian entrainment	35/432	136/7206	6.03884194824e-14
ko04725	Cholinergic synapse	35/432	160/7206	1.01954285876e-11
ko04726	Serotonergic synapse	30/432	137/7206	3.16667574226e-10
ko04966	Collecting duct acid secretion	13/432	26/7206	5.49822766723e-10
ko04024	cAMP signaling pathway	43/432	279/7206	6.30633572977e-09
ko04911	Insulin secretion	25/432	117/7206	1.68266671557e-08
ko05031	Amphetamine addiction	21/432	91/7206	5.87620690595e-08
ko05030	Cocaine addiction	18/432	73/7206	1.80006865997e-07
ko05110	Vibrio cholerae infection	16/432	63/7206	5.6650828472e-07
ko04970	Salivary secretion	20/432	95/7206	6.01140104632e-07
ko04921	Oxytocin signaling pathway	32/432	209/7206	7.01867112324e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	17/432	74/7206	1.16898652702e-06
ko04261	Adrenergic signaling in cardiomyocytes	31/432	205/7206	1.38564388115e-06
ko05120	Epithelial cell signaling in Helicobacter pylori infection	18/432	92/7206	6.64959299215e-06
ko04720	Long-term potentiation	18/432	99/7206	1.92645871045e-05
ko04972	Pancreatic secretion	19/432	111/7206	2.76428825864e-05
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/432	59/7206	3.45254800877e-05
ko04971	Gastric acid secretion	17/432	98/7206	6.1174503997e-05
ko05323	Rheumatoid arthritis	16/432	89/7206	6.42879611407e-05
ko04060	Cytokine-cytokine receptor interaction	1/432	191/7206	0.000150562340019
ko04540	Gap junction	19/432	128/7206	0.000201839601953
ko04744	Phototransduction	9/432	36/7206	0.000202520610475
ko04964	Proximal tubule bicarbonate reclamation	8/432	29/7206	0.000219252480475
ko04145	Phagosome	22/432	162/7206	0.000284028789629
ko00190	Oxidative phosphorylation	18/432	127/7206	0.000525659041415
ko04010	MAPK signaling pathway	35/432	321/7206	0.000636833560989
ko04730	Long-term depression	13/432	78/7206	0.000663033160969
ko04742	Taste transduction	11/432	61/7206	0.000865428252749
ko04925	Aldosterone synthesis and secretion	15/432	105/7206	0.00138629717378
ko04020	Calcium signaling pathway	29/432	265/7206	0.00139623539283
ko05322	Systemic lupus erythematosus	1/432	151/7206	0.00150829009779
ko04924	Renin secretion	13/432	86/7206	0.00169068844164
ko04022	cGMP-PKG signaling pathway	25/432	216/7206	0.00185796930401
ko03040	Spliceosome	1/432	145/7206	0.0022127603077
ko04120	Ubiquitin mediated proteolysis	1/432	138/7206	0.00322379235861
ko05164	Influenza A	2/432	167/7206	0.00431693311387
ko05168	Herpes simplex infection	3/432	182/7206	0.00682735748955
ko04260	Cardiac muscle contraction	13/432	98/7206	0.00767458097103
ko05203	Viral carcinogenesis	7/432	277/7206	0.00943097210075
ko05034	Alcoholism	24/432	238/7206	0.0116000753052
ko04510	Focal adhesion	6/432	240/7206	0.0177419157972
ko05010	Alzheimer's disease	20/432	202/7206	0.0235176949752
ko04371	Apelin signaling pathway	18/432	177/7206	0.0240727125765
ko04976	Bile secretion	10/432	80/7206	0.0274526499391
ko04978	Mineral absorption	6/432	40/7206	0.0303936827068
ko05166	HTLV-I infection	9/432	292/7206	0.0314928029685
ko04960	Aldosterone-regulated sodium reabsorption	6/432	41/7206	0.0338723122077
ko04918	Thyroid hormone synthesis	10/432	86/7206	0.036952560715
ko04015	Rap1 signaling pathway	25/432	278/7206	0.0385020967081
ko04014	Ras signaling pathway	25/432	279/7206	0.0391269975738
ko04940	Type I diabetes mellitus	5/432	32/7206	0.0399190836218
ko04072	Phospholipase D signaling pathway	19/432	197/7206	0.0455265347607
ko03013	RNA transport	4/432	166/7206	0.0464012545136
ko04114	Oocyte meiosis	14/432	139/7206	0.0470718233363
ko04062	Chemokine signaling pathway	19/432	201/7206	0.048040882549