ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 24/154 191/7206 1.33618957366e-12 ko04621 NOD-like receptor signaling pathway 20/154 157/7206 9.08739771967e-11 ko05164 Influenza A 20/154 167/7206 2.81996164343e-10 ko04380 Osteoclast differentiation 17/154 134/7206 2.75560656221e-09 ko04217 Necroptosis 18/154 178/7206 3.53056712427e-08 ko04658 Th1 and Th2 cell differentiation 13/154 96/7206 1.02172958079e-07 ko04064 NF-kappa B signaling pathway 13/154 96/7206 1.02172958079e-07 ko05340 Primary immunodeficiency 8/154 30/7206 1.42482953995e-07 ko04650 Natural killer cell mediated cytotoxicity 12/154 97/7206 8.80803905512e-07 ko05162 Measles 13/154 120/7206 1.42534179635e-06 ko05168 Herpes simplex infection 16/154 182/7206 1.44240898618e-06 ko04660 T cell receptor signaling pathway 13/154 124/7206 2.07416876171e-06 ko05321 Inflammatory bowel disease (IBD) 9/154 56/7206 2.36425169342e-06 ko05145 Toxoplasmosis 13/154 126/7206 2.48792657009e-06 ko05323 Rheumatoid arthritis 11/154 89/7206 2.58593237625e-06 ko05140 Leishmaniasis 10/154 75/7206 3.73474276673e-06 ko04630 Jak-STAT signaling pathway 13/154 132/7206 4.20321848869e-06 ko05160 Hepatitis C 14/154 153/7206 4.24478200073e-06 ko04620 Toll-like receptor signaling pathway 11/154 100/7206 8.19491896727e-06 ko05152 Tuberculosis 15/154 187/7206 9.70190670115e-06 ko04659 Th17 cell differentiation 11/154 106/7206 1.44080624222e-05 ko04612 Antigen processing and presentation 9/154 77/7206 3.43414922969e-05 ko04668 TNF signaling pathway 11/154 120/7206 4.65321609189e-05 ko05167 Kaposi's sarcoma-associated herpesvirus infection 14/154 191/7206 5.33264295315e-05 ko05131 Shigellosis 9/154 82/7206 5.6959650381e-05 ko05133 Pertussis 9/154 87/7206 9.10311577316e-05 ko04062 Chemokine signaling pathway 14/154 201/7206 9.28988676152e-05 ko04672 Intestinal immune network for IgA production 6/154 37/7206 0.00011616518903 ko05161 Hepatitis B 12/154 173/7206 0.000310416083004 ko04662 B cell receptor signaling pathway 8/154 88/7206 0.00054846384352 ko04145 Phagosome 11/154 162/7206 0.00066337343025 ko05132 Salmonella infection 8/154 98/7206 0.00112187411245 ko05330 Allograft rejection 4/154 24/7206 0.00152719393154 ko04623 Cytosolic DNA-sensing pathway 5/154 41/7206 0.00168259897648 ko04622 RIG-I-like receptor signaling pathway 6/154 62/7206 0.00198051363239 ko04933 AGE-RAGE signaling pathway in diabetic complications 9/154 135/7206 0.00232464117385 ko04657 IL-17 signaling pathway 7/154 87/7206 0.00248393045117 ko05144 Malaria 5/154 45/7206 0.00256165075345 ko04666 Fc gamma R-mediated phagocytosis 8/154 122/7206 0.00446574408144 ko05134 Legionellosis 6/154 74/7206 0.0048408969416 ko04670 Leukocyte transendothelial migration 9/154 151/7206 0.00491621249923 ko05310 Asthma 3/154 17/7206 0.00522301417858 ko05166 HTLV-I infection 14/154 292/7206 0.00535278460354 ko03050 Proteasome 5/154 54/7206 0.00568689831858 ko05332 Graft-versus-host disease 3/154 18/7206 0.00617042925531 ko04610 Complement and coagulation cascades 6/154 79/7206 0.00665868898987 ko05150 Staphylococcus aureus infection 4/154 36/7206 0.00694264433581 ko04917 Prolactin signaling pathway 6/154 87/7206 0.0105294849605 ko00051 Fructose and mannose metabolism 4/154 42/7206 0.0119540023905 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/154 92/7206 0.0136361336545 ko04210 Apoptosis 9/154 180/7206 0.0147707707203 ko04142 Lysosome 8/154 151/7206 0.015361763466 ko05146 Amoebiasis 6/154 99/7206 0.0189894742576 ko05142 Chagas disease (American trypanosomiasis) 7/154 130/7206 0.0210576089337 ko05320 Autoimmune thyroid disease 3/154 29/7206 0.0232920276276 ko05416 Viral myocarditis 4/154 55/7206 0.0294640355232 ko04940 Type I diabetes mellitus 3/154 32/7206 0.0301884557279 ko05169 Epstein-Barr virus infection 9/154 206/7206 0.0430349308087 ko04640 Hematopoietic cell lineage 4/154 64/7206 0.0474546241902