ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 20/535 36/7206 4.37730255992e-14 ko05032 Morphine addiction 29/535 110/7206 8.74727537787e-10 ko04727 GABAergic synapse 24/535 110/7206 1.16765024939e-06 ko05033 Nicotine addiction 16/535 56/7206 1.73991568287e-06 ko04080 Neuroactive ligand-receptor interaction 55/535 423/7206 3.23794511146e-05 ko04725 Cholinergic synapse 27/535 160/7206 4.52141399232e-05 ko04360 Axon guidance 35/535 233/7206 5.7496012011e-05 ko04723 Retrograde endocannabinoid signaling 28/535 175/7206 9.76865486144e-05 ko04724 Glutamatergic synapse 25/535 152/7206 0.000128988179365 ko04070 Phosphatidylinositol signaling system 20/535 112/7206 0.000185535459054 ko05322 Systemic lupus erythematosus 1/535 151/7206 0.000212122487816 ko04726 Serotonergic synapse 22/535 137/7206 0.000717207110073 ko04710 Circadian rhythm 10/535 43/7206 0.0009559632995 ko04024 cAMP signaling pathway 36/535 279/7206 0.000983434383003 ko04911 Insulin secretion 19/535 117/7206 0.00102460364628 ko04721 Synaptic vesicle cycle 14/535 80/7206 0.00204128585203 ko05016 Huntington's disease 5/535 215/7206 0.00207338837415 ko03013 RNA transport 3/535 166/7206 0.00237679524892 ko05164 Influenza A 3/535 167/7206 0.00240552569451 ko00604 Glycosphingolipid biosynthesis - ganglio series 5/535 14/7206 0.0025215691763 ko05203 Viral carcinogenesis 9/535 277/7206 0.00471097687882 ko04728 Dopaminergic synapse 24/535 185/7206 0.00645121797436 ko04010 MAPK signaling pathway 36/535 321/7206 0.0118029307655 ko05323 Rheumatoid arthritis 1/535 89/7206 0.0137984341364 ko04964 Proximal tubule bicarbonate reclamation 6/535 29/7206 0.0177850582608 ko04072 Phospholipase D signaling pathway 24/535 197/7206 0.0178973259181 ko04713 Circadian entrainment 18/535 136/7206 0.0188553437865 ko03018 RNA degradation 1/535 84/7206 0.0200620328829 ko00562 Inositol phosphate metabolism 13/535 89/7206 0.0218750958097 ko04020 Calcium signaling pathway 30/535 265/7206 0.0223047420656 ko05152 Tuberculosis 6/535 187/7206 0.0228525283465 ko04514 Cell adhesion molecules (CAMs) 17/535 130/7206 0.0258688025343 ko04014 Ras signaling pathway 31/535 279/7206 0.0258870019761 ko04610 Complement and coagulation cascades 1/535 79/7206 0.0291487137875 ko04960 Aldosterone-regulated sodium reabsorption 7/535 41/7206 0.0295091301741 ko05168 Herpes simplex infection 6/535 182/7206 0.0304544132232 ko04145 Phagosome 5/535 162/7206 0.03237046623 ko05132 Salmonella infection 2/535 98/7206 0.0328736626325 ko04620 Toll-like receptor signaling pathway 2/535 100/7206 0.0329719888959 ko04742 Taste transduction 9/535 61/7206 0.0436243451198 ko04612 Antigen processing and presentation 1/535 77/7206 0.044364579961 ko04380 Osteoclast differentiation 4/535 134/7206 0.0452368631435 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 11/535 79/7206 0.0468364213623