ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	88/415	423/7206	3.28900022201e-28
ko05033	Nicotine addiction	33/415	56/7206	3.35751461815e-27
ko04724	Glutamatergic synapse	48/415	152/7206	1.01496087647e-23
ko04727	GABAergic synapse	34/415	110/7206	9.61503287419e-17
ko04713	Circadian entrainment	37/415	136/7206	4.29284758722e-16
ko04723	Retrograde endocannabinoid signaling	41/415	175/7206	3.1526138557e-15
ko04728	Dopaminergic synapse	42/415	185/7206	4.67389583534e-15
ko05032	Morphine addiction	30/415	110/7206	2.72366004243e-13
ko04725	Cholinergic synapse	32/415	160/7206	3.35597461747e-10
ko05031	Amphetamine addiction	23/415	91/7206	9.33081831496e-10
ko04024	cAMP signaling pathway	43/415	279/7206	1.83076979029e-09
ko04726	Serotonergic synapse	28/415	137/7206	2.66431358949e-09
ko04742	Taste transduction	18/415	61/7206	4.44951826228e-09
ko04721	Synaptic vesicle cycle	20/415	80/7206	1.45912418025e-08
ko05030	Cocaine addiction	19/415	73/7206	1.64851596632e-08
ko04911	Insulin secretion	24/415	117/7206	3.48497843955e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	18/415	74/7206	1.22714581659e-07
ko04261	Adrenergic signaling in cardiomyocytes	30/415	205/7206	1.79959702548e-06
ko04970	Salivary secretion	18/415	95/7206	6.09622529091e-06
ko04720	Long-term potentiation	18/415	99/7206	1.11370815778e-05
ko04921	Oxytocin signaling pathway	29/415	209/7206	1.13161377297e-05
ko04020	Calcium signaling pathway	31/415	265/7206	0.000132831602113
ko04514	Cell adhesion molecules (CAMs)	19/415	130/7206	0.000147447976176
ko04730	Long-term depression	13/415	78/7206	0.000452582637369
ko04972	Pancreatic secretion	16/415	111/7206	0.000569019168596
ko05164	Influenza A	1/415	167/7206	0.00107047032024
ko04360	Axon guidance	26/415	233/7206	0.00135275361579
ko04260	Cardiac muscle contraction	14/415	98/7206	0.00135545270576
ko04060	Cytokine-cytokine receptor interaction	2/415	191/7206	0.00145014712847
ko05034	Alcoholism	26/415	238/7206	0.00155475110386
ko04010	MAPK signaling pathway	32/415	321/7206	0.00201436269462
ko04510	Focal adhesion	4/415	240/7206	0.0027623261443
ko05168	Herpes simplex infection	2/415	182/7206	0.00309427791382
ko03040	Spliceosome	1/415	145/7206	0.00328343799584
ko04971	Gastric acid secretion	13/415	98/7206	0.00387474691725
ko04120	Ubiquitin mediated proteolysis	1/415	138/7206	0.00478066812564
ko04964	Proximal tubule bicarbonate reclamation	6/415	29/7206	0.00538432503595
ko04961	Endocrine and other factor-regulated calcium reabsorption	9/415	59/7206	0.00615602542565
ko04925	Aldosterone synthesis and secretion	13/415	105/7206	0.00887677050471
ko04150	mTOR signaling pathway	3/415	184/7206	0.00960317063624
ko04930	Type II diabetes mellitus	8/415	54/7206	0.0114064188304
ko05162	Measles	1/415	120/7206	0.0152478461884
ko04022	cGMP-PKG signaling pathway	21/415	216/7206	0.0167539068826
ko05203	Viral carcinogenesis	7/415	277/7206	0.0169280277641
ko05010	Alzheimer's disease	20/415	202/7206	0.019854904742
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	10/415	79/7206	0.0236556369031
ko04014	Ras signaling pathway	25/415	279/7206	0.0251684621489
ko04978	Mineral absorption	6/415	40/7206	0.0255659157273
ko04960	Aldosterone-regulated sodium reabsorption	6/415	41/7206	0.028546942007
ko04924	Renin secretion	10/415	86/7206	0.0311989103272
ko00513	Various types of N-glycan biosynthesis	6/415	42/7206	0.03174819949
ko04973	Carbohydrate digestion and absorption	6/415	42/7206	0.03174819949
ko04621	NOD-like receptor signaling pathway	3/415	157/7206	0.0355429208259
ko05205	Proteoglycans in cancer	8/415	271/7206	0.044947690279
ko00564	Glycerophospholipid metabolism	1/415	99/7206	0.0457160762918
ko05161	Hepatitis B	4/415	173/7206	0.0465813270259
ko04962	Vasopressin-regulated water reabsorption	7/415	58/7206	0.0476149773625
ko04740	Olfactory transduction	9/415	80/7206	0.0480162341634
ko05322	Systemic lupus erythematosus	3/415	151/7206	0.0491970382919