ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	199/1202	423/7206	1.89048500178e-51
ko04724	Glutamatergic synapse	91/1202	152/7206	5.89758173991e-34
ko05032	Morphine addiction	70/1202	110/7206	1.15087439971e-28
ko05033	Nicotine addiction	47/1202	56/7206	2.09251480765e-28
ko04727	GABAergic synapse	68/1202	110/7206	9.02363329211e-27
ko04713	Circadian entrainment	77/1202	136/7206	1.29599292825e-26
ko04725	Cholinergic synapse	80/1202	160/7206	7.32564169519e-23
ko04721	Synaptic vesicle cycle	52/1202	80/7206	3.33966797623e-22
ko04728	Dopaminergic synapse	86/1202	185/7206	9.07836417174e-22
ko04723	Retrograde endocannabinoid signaling	80/1202	175/7206	9.35481566603e-20
ko04020	Calcium signaling pathway	104/1202	265/7206	3.27956128142e-19
ko04024	cAMP signaling pathway	105/1202	279/7206	8.34566495854e-18
ko04911	Insulin secretion	59/1202	117/7206	2.24161586585e-17
ko04726	Serotonergic synapse	63/1202	137/7206	5.97686965254e-16
ko04921	Oxytocin signaling pathway	81/1202	209/7206	8.45996012277e-15
ko04742	Taste transduction	37/1202	61/7206	9.94744822091e-15
ko04970	Salivary secretion	46/1202	95/7206	5.38210222252e-13
ko04744	Phototransduction	25/1202	36/7206	2.65672421466e-12
ko04261	Adrenergic signaling in cardiomyocytes	75/1202	205/7206	2.93265792248e-12
ko04720	Long-term potentiation	45/1202	99/7206	1.53947920897e-11
ko05031	Amphetamine addiction	42/1202	91/7206	4.01716364415e-11
ko03040	Spliceosome	1/1202	145/7206	1.17408591815e-10
ko04925	Aldosterone synthesis and secretion	43/1202	105/7206	2.49309650155e-09
ko04971	Gastric acid secretion	40/1202	98/7206	1.00952862738e-08
ko04022	cGMP-PKG signaling pathway	67/1202	216/7206	1.28659147325e-07
ko04360	Axon guidance	70/1202	233/7206	2.46013716091e-07
ko05203	Viral carcinogenesis	18/1202	277/7206	4.08232099188e-07
ko05168	Herpes simplex infection	8/1202	182/7206	4.94529978237e-07
ko03013	RNA transport	7/1202	166/7206	8.62579348952e-07
ko04972	Pancreatic secretion	40/1202	111/7206	9.30528163086e-07
ko04740	Olfactory transduction	31/1202	80/7206	2.19176342185e-06
ko05322	Systemic lupus erythematosus	6/1202	151/7206	2.24371174473e-06
ko04070	Phosphatidylinositol signaling system	39/1202	112/7206	2.39884191659e-06
ko04966	Collecting duct acid secretion	15/1202	26/7206	2.44882284457e-06
ko04540	Gap junction	43/1202	128/7206	3.14252285692e-06
ko05030	Cocaine addiction	28/1202	73/7206	8.56108456995e-06
ko04730	Long-term depression	29/1202	78/7206	1.05218869798e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1202	74/7206	1.08143637167e-05
ko04010	MAPK signaling pathway	84/1202	321/7206	1.0866417086e-05
ko04514	Cell adhesion molecules (CAMs)	41/1202	130/7206	2.37967244907e-05
ko04014	Ras signaling pathway	74/1202	279/7206	2.51181463627e-05
ko04072	Phospholipase D signaling pathway	56/1202	197/7206	2.62057576078e-05
ko04060	Cytokine-cytokine receptor interaction	12/1202	191/7206	2.85125806005e-05
ko05110	Vibrio cholerae infection	24/1202	63/7206	4.55980919612e-05
ko04745	Phototransduction - fly	17/1202	38/7206	4.57939022339e-05
ko04621	NOD-like receptor signaling pathway	9/1202	157/7206	5.05297169099e-05
ko04141	Protein processing in endoplasmic reticulum	12/1202	184/7206	5.20371694376e-05
ko05164	Influenza A	10/1202	167/7206	5.26675392869e-05
ko04976	Bile secretion	28/1202	80/7206	5.79433658979e-05
ko04750	Inflammatory mediator regulation of TRP channels	38/1202	122/7206	6.7274092959e-05
ko04110	Cell cycle	8/1202	145/7206	6.77610557332e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1202	79/7206	0.000111343867541
ko04961	Endocrine and other factor-regulated calcium reabsorption	22/1202	59/7206	0.000129860417839
ko05414	Dilated cardiomyopathy	35/1202	112/7206	0.000160112933544
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1202	79/7206	0.000181960778966
ko04120	Ubiquitin mediated proteolysis	8/1202	138/7206	0.000187180975719
ko04915	Estrogen signaling pathway	39/1202	131/7206	0.000196154675737
ko04923	Regulation of lipolysis in adipocytes	26/1202	77/7206	0.000282634839367
ko04964	Proximal tubule bicarbonate reclamation	13/1202	29/7206	0.000352706655875
ko04924	Renin secretion	28/1202	86/7206	0.000353827025486
ko04371	Apelin signaling pathway	48/1202	177/7206	0.000455311456372
ko04260	Cardiac muscle contraction	30/1202	98/7206	0.000544592588583
ko04612	Antigen processing and presentation	3/1202	77/7206	0.00102036091219
ko04626	Plant-pathogen interaction	9/1202	18/7206	0.00111986661857
ko05169	Epstein-Barr virus infection	18/1202	206/7206	0.00119292898677
ko04064	NF-kappa B signaling pathway	5/1202	96/7206	0.00128835169887
ko04270	Vascular smooth muscle contraction	41/1202	154/7206	0.00145897698846
ko05140	Leishmaniasis	3/1202	75/7206	0.00150675728908
ko04912	GnRH signaling pathway	33/1202	122/7206	0.00317186622621
ko04710	Circadian rhythm	15/1202	43/7206	0.00326140201185
ko04918	Thyroid hormone synthesis	25/1202	86/7206	0.00342263951545
ko05162	Measles	9/1202	120/7206	0.00432402742403
ko05144	Malaria	1/1202	45/7206	0.00434015070823
ko00071	Fatty acid degradation	1/1202	45/7206	0.00434015070823
ko03420	Nucleotide excision repair	1/1202	46/7206	0.00444282643432
ko04015	Rap1 signaling pathway	64/1202	278/7206	0.00517876704093
ko05205	Proteoglycans in cancer	29/1202	271/7206	0.00599768076945
ko00562	Inositol phosphate metabolism	25/1202	89/7206	0.00613426873249
ko03022	Basal transcription factors	1/1202	44/7206	0.00684115835769
ko04922	Glucagon signaling pathway	33/1202	128/7206	0.00810418506127
ko00590	Arachidonic acid metabolism	2/1202	52/7206	0.00818753983349
ko00330	Arginine and proline metabolism	3/1202	61/7206	0.00909605081121
ko04330	Notch signaling pathway	3/1202	62/7206	0.00923295990359
ko04622	RIG-I-like receptor signaling pathway	3/1202	62/7206	0.00923295990359
ko04146	Peroxisome	6/1202	89/7206	0.00932387944438
ko04610	Complement and coagulation cascades	5/1202	79/7206	0.00948048907378
ko05166	HTLV-I infection	33/1202	292/7206	0.0102632497067
ko04973	Carbohydrate digestion and absorption	14/1202	42/7206	0.01058780042
ko04658	Th1 and Th2 cell differentiation	7/1202	96/7206	0.0122408695677
ko05161	Hepatitis B	17/1202	173/7206	0.0129165400157
ko05133	Pertussis	6/1202	87/7206	0.0129280510728
ko00240	Pyrimidine metabolism	9/1202	110/7206	0.0138309401737
ko04217	Necroptosis	18/1202	178/7206	0.0145458638874
ko05145	Toxoplasmosis	11/1202	126/7206	0.015231199438
ko04930	Type II diabetes mellitus	16/1202	54/7206	0.0160584153763
ko04916	Melanogenesis	35/1202	142/7206	0.0162720013683
ko03018	RNA degradation	6/1202	84/7206	0.0174459585195
ko04630	Jak-STAT signaling pathway	12/1202	132/7206	0.0177931273679
ko04115	p53 signaling pathway	5/1202	74/7206	0.0180879527206
ko04960	Aldosterone-regulated sodium reabsorption	13/1202	41/7206	0.0181216106872
ko05321	Inflammatory bowel disease (IBD)	3/1202	56/7206	0.0184712859561
ko05231	Choline metabolism in cancer	33/1202	134/7206	0.0185861660158
ko04213	Longevity regulating pathway - multiple species	23/1202	86/7206	0.018706673764
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1202	14/7206	0.0190466404886
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1202	100/7206	0.0205550026247
ko04062	Chemokine signaling pathway	46/1202	201/7206	0.0209287408993
ko05202	Transcriptional misregulation in cancer	20/1202	188/7206	0.0224685293096
ko05214	Glioma	21/1202	79/7206	0.0225058188856
ko05131	Shigellosis	6/1202	82/7206	0.024012432744
ko04214	Apoptosis - fly	5/1202	72/7206	0.0249629785783
ko00310	Lysine degradation	5/1202	73/7206	0.0255273501748
ko00280	Valine, leucine and isoleucine degradation	3/1202	54/7206	0.0263411355238
ko04640	Hematopoietic cell lineage	4/1202	64/7206	0.0266602587588
ko00480	Glutathione metabolism	3/1202	55/7206	0.0270956943821
ko04657	IL-17 signaling pathway	7/1202	87/7206	0.0291148390478
ko00860	Porphyrin and chlorophyll metabolism	1/1202	34/7206	0.0340992504901
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1202	182/7206	0.0346011130403
ko04210	Apoptosis	20/1202	180/7206	0.0426417304807
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1202	92/7206	0.0471566273409
ko05340	Primary immunodeficiency	1/1202	30/7206	0.0487231603801