ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	204/1207	423/7206	9.7783274594e-55
ko05033	Nicotine addiction	49/1207	56/7206	2.87824158769e-31
ko04724	Glutamatergic synapse	88/1207	152/7206	3.67190809119e-31
ko05032	Morphine addiction	69/1207	110/7206	1.34956962625e-27
ko04727	GABAergic synapse	67/1207	110/7206	9.68259363703e-26
ko04713	Circadian entrainment	75/1207	136/7206	7.64767053083e-25
ko04721	Synaptic vesicle cycle	51/1207	80/7206	3.79370268331e-21
ko04728	Dopaminergic synapse	85/1207	185/7206	5.51278595352e-21
ko04725	Cholinergic synapse	76/1207	160/7206	6.12368504834e-20
ko04723	Retrograde endocannabinoid signaling	78/1207	175/7206	2.29713625398e-18
ko04024	cAMP signaling pathway	105/1207	279/7206	1.08902176611e-17
ko04020	Calcium signaling pathway	101/1207	265/7206	2.48319847381e-17
ko04742	Taste transduction	38/1207	61/7206	1.39706551726e-15
ko04911	Insulin secretion	56/1207	117/7206	3.50772776101e-15
ko04726	Serotonergic synapse	61/1207	137/7206	1.37285097059e-14
ko04744	Phototransduction	26/1207	36/7206	2.4150162207e-13
ko04921	Oxytocin signaling pathway	78/1207	209/7206	5.15011590322e-13
ko04720	Long-term potentiation	45/1207	99/7206	1.78253842475e-11
ko04261	Adrenergic signaling in cardiomyocytes	73/1207	205/7206	3.12212373295e-11
ko03040	Spliceosome	1/1207	145/7206	1.1733727827e-10
ko05031	Amphetamine addiction	41/1207	91/7206	2.00187361493e-10
ko04970	Salivary secretion	42/1207	95/7206	2.5089805081e-10
ko04740	Olfactory transduction	36/1207	80/7206	2.68109966052e-09
ko05203	Viral carcinogenesis	15/1207	277/7206	9.56327292449e-09
ko04360	Axon guidance	74/1207	233/7206	1.02686192542e-08
ko04022	cGMP-PKG signaling pathway	69/1207	216/7206	2.60135880334e-08
ko04060	Cytokine-cytokine receptor interaction	8/1207	191/7206	1.11665190519e-07
ko04971	Gastric acid secretion	38/1207	98/7206	1.48134452855e-07
ko05322	Systemic lupus erythematosus	5/1207	151/7206	3.85960397501e-07
ko04925	Aldosterone synthesis and secretion	39/1207	105/7206	4.33030657598e-07
ko05030	Cocaine addiction	30/1207	73/7206	6.5160275451e-07
ko03013	RNA transport	7/1207	166/7206	8.52164362907e-07
ko05168	Herpes simplex infection	9/1207	182/7206	1.59869194056e-06
ko04966	Collecting duct acid secretion	15/1207	26/7206	2.58525681919e-06
ko05164	Influenza A	8/1207	167/7206	2.9232556635e-06
ko04540	Gap junction	43/1207	128/7206	3.26458561305e-06
ko04972	Pancreatic secretion	38/1207	111/7206	7.63880600734e-06
ko05169	Epstein-Barr virus infection	13/1207	206/7206	1.04519383619e-05
ko04730	Long-term depression	29/1207	78/7206	1.13427551598e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	28/1207	74/7206	1.15465461921e-05
ko04924	Renin secretion	31/1207	86/7206	1.362921825e-05
ko04120	Ubiquitin mediated proteolysis	6/1207	138/7206	1.41379082636e-05
ko04010	MAPK signaling pathway	83/1207	321/7206	2.30344143372e-05
ko04514	Cell adhesion molecules (CAMs)	41/1207	130/7206	2.54189295793e-05
ko05110	Vibrio cholerae infection	24/1207	63/7206	4.7716033077e-05
ko04745	Phototransduction - fly	17/1207	38/7206	4.83800747184e-05
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	28/1207	79/7206	5.02944108392e-05
ko04621	NOD-like receptor signaling pathway	9/1207	157/7206	5.06791690874e-05
ko04141	Protein processing in endoplasmic reticulum	12/1207	184/7206	5.21371189641e-05
ko04610	Complement and coagulation cascades	2/1207	79/7206	0.00011049557844
ko03008	Ribosome biogenesis in eukaryotes	2/1207	79/7206	0.00011049557844
ko04072	Phospholipase D signaling pathway	54/1207	197/7206	0.000139687106938
ko04070	Phosphatidylinositol signaling system	35/1207	112/7206	0.000163985208888
ko04976	Bile secretion	27/1207	80/7206	0.000208227666688
ko05140	Leishmaniasis	2/1207	75/7206	0.000249982822927
ko04110	Cell cycle	9/1207	145/7206	0.000270327526542
ko04064	NF-kappa B signaling pathway	4/1207	96/7206	0.000271665051892
ko04014	Ras signaling pathway	70/1207	279/7206	0.000297356492302
ko05414	Dilated cardiomyopathy	34/1207	112/7206	0.000299569402981
ko04260	Cardiac muscle contraction	31/1207	98/7206	0.000302515016091
ko05205	Proteoglycans in cancer	25/1207	271/7206	0.000458997567567
ko05162	Measles	7/1207	120/7206	0.00048990356792
ko04750	Inflammatory mediator regulation of TRP channels	36/1207	122/7206	0.000513385746381
ko04961	Endocrine and other factor-regulated calcium reabsorption	21/1207	59/7206	0.00060010482064
ko04146	Peroxisome	4/1207	89/7206	0.000826917476897
ko04612	Antigen processing and presentation	3/1207	77/7206	0.0010254142373
ko04626	Plant-pathogen interaction	9/1207	18/7206	0.00115510902029
ko04964	Proximal tubule bicarbonate reclamation	12/1207	29/7206	0.00146605113699
ko04915	Estrogen signaling pathway	36/1207	131/7206	0.00192550113505
ko04932	Non-alcoholic fatty liver disease (NAFLD)	16/1207	182/7206	0.0024417726436
ko05161	Hepatitis B	15/1207	173/7206	0.00268169226167
ko04371	Apelin signaling pathway	45/1207	177/7206	0.00295270285863
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1207	14/7206	0.00419083387436
ko05144	Malaria	1/1207	45/7206	0.00433068858039
ko00071	Fatty acid degradation	1/1207	45/7206	0.00433068858039
ko03420	Nucleotide excision repair	1/1207	46/7206	0.00446617269236
ko01524	Platinum drug resistance	4/1207	76/7206	0.00482245269442
ko03018	RNA degradation	5/1207	84/7206	0.00488063354874
ko05145	Toxoplasmosis	10/1207	126/7206	0.00540191778882
ko00480	Glutathione metabolism	2/1207	55/7206	0.00565247557692
ko05321	Inflammatory bowel disease (IBD)	2/1207	56/7206	0.00591183375849
ko00240	Pyrimidine metabolism	8/1207	110/7206	0.00634167575476
ko04640	Hematopoietic cell lineage	3/1207	64/7206	0.00638330722149
ko04214	Apoptosis - fly	4/1207	72/7206	0.00671134011183
ko00310	Lysine degradation	4/1207	73/7206	0.00674828764132
ko05131	Shigellosis	5/1207	82/7206	0.00684185086332
ko03022	Basal transcription factors	1/1207	44/7206	0.00689652264893
ko04923	Regulation of lipolysis in adipocytes	22/1207	77/7206	0.00850126570722
ko04658	Th1 and Th2 cell differentiation	7/1207	96/7206	0.00882880237207
ko04330	Notch signaling pathway	3/1207	62/7206	0.00927721666049
ko04622	RIG-I-like receptor signaling pathway	3/1207	62/7206	0.00927721666049
ko05410	Hypertrophic cardiomyopathy (HCM)	27/1207	100/7206	0.00968131549503
ko05418	Fluid shear stress and atherosclerosis	17/1207	173/7206	0.0129549520954
ko04657	IL-17 signaling pathway	6/1207	87/7206	0.0130330206688
ko05133	Pertussis	6/1207	87/7206	0.0130330206688
ko04912	GnRH signaling pathway	31/1207	122/7206	0.0139184086993
ko00630	Glyoxylate and dicarboxylate metabolism	1/1207	38/7206	0.0147715516633
ko03410	Base excision repair	1/1207	38/7206	0.0147715516633
ko04620	Toll-like receptor signaling pathway	8/1207	100/7206	0.0149563552301
ko05166	HTLV-I infection	34/1207	292/7206	0.0162070305857
ko04916	Melanogenesis	35/1207	142/7206	0.0164722358337
ko04630	Jak-STAT signaling pathway	12/1207	132/7206	0.0178960467761
ko04115	p53 signaling pathway	5/1207	74/7206	0.0180815244336
ko05231	Choline metabolism in cancer	33/1207	134/7206	0.0188903173265
ko04015	Rap1 signaling pathway	61/1207	278/7206	0.0216038041084
ko05222	Small cell lung cancer	7/1207	89/7206	0.021674255077
ko04668	TNF signaling pathway	11/1207	120/7206	0.0256508784147
ko04270	Vascular smooth muscle contraction	36/1207	154/7206	0.0292486453761
ko04978	Mineral absorption	12/1207	40/7206	0.0325555148941
ko04113	Meiosis - yeast	5/1207	70/7206	0.0346629550678
ko03015	mRNA surveillance pathway	8/1207	93/7206	0.0350900294624
ko00140	Steroid hormone biosynthesis	2/1207	41/7206	0.0362924300538
ko00330	Arginine and proline metabolism	4/1207	61/7206	0.0366450457793
ko00380	Tryptophan metabolism	3/1207	50/7206	0.0368409216118
ko00590	Arachidonic acid metabolism	3/1207	52/7206	0.037809794323
ko05132	Salmonella infection	9/1207	98/7206	0.0411903370874
ko04930	Type II diabetes mellitus	15/1207	54/7206	0.0417889869019
ko01200	Carbon metabolism	13/1207	128/7206	0.0423704439188
ko04210	Apoptosis	20/1207	180/7206	0.0426742568892
ko04140	Autophagy - animal	18/1207	164/7206	0.0444375611308
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1207	92/7206	0.0475099863795