ko pathway ratio_in_study ratio_in_pop p_value ko03008 Ribosome biogenesis in eukaryotes 24/325 79/7206 2.5811373874e-14 ko03030 DNA replication 17/325 38/7206 1.06399812092e-13 ko04110 Cell cycle 28/325 145/7206 3.64389984895e-11 ko03410 Base excision repair 14/325 38/7206 3.95504988877e-10 ko03040 Spliceosome 26/325 145/7206 1.02872670201e-09 ko05217 Basal cell carcinoma 16/325 68/7206 3.52138287186e-08 ko04550 Signaling pathways regulating pluripotency of stem cells 25/325 165/7206 7.45404815096e-08 ko04111 Cell cycle - yeast 16/325 90/7206 2.07869731561e-06 ko04950 Maturity onset diabetes of the young 8/325 29/7206 2.9341661606e-05 ko04020 Calcium signaling pathway 1/325 265/7206 0.000109270857003 ko05206 MicroRNAs in cancer 20/325 177/7206 0.00012850022168 ko03420 Nucleotide excision repair 9/325 46/7206 0.000173539672375 ko04340 Hedgehog signaling pathway 10/325 58/7206 0.000229101290357 ko05224 Breast cancer 19/325 174/7206 0.000295377069892 ko04350 TGF-beta signaling pathway 13/325 103/7206 0.000684569330045 ko04144 Endocytosis 4/325 342/7206 0.000732878267118 ko05202 Transcriptional misregulation in cancer 19/325 188/7206 0.000933231797207 ko04113 Meiosis - yeast 10/325 70/7206 0.00107807223674 ko00240 Pyrimidine metabolism 13/325 110/7206 0.00127701650453 ko04062 Chemokine signaling pathway 1/325 201/7206 0.00157999546254 ko05010 Alzheimer's disease 1/325 202/7206 0.00158840834371 ko04330 Notch signaling pathway 9/325 62/7206 0.00169407661958 ko05166 HTLV-I infection 25/325 292/7206 0.00209077519704 ko04390 Hippo signaling pathway 18/325 188/7206 0.00212996152229 ko04072 Phospholipase D signaling pathway 1/325 197/7206 0.00241941413616 ko03430 Mismatch repair 5/325 22/7206 0.00252565673047 ko05200 Pathways in cancer 36/325 492/7206 0.00329429234263 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/325 182/7206 0.00335271960276 ko05222 Small cell lung cancer 10/325 89/7206 0.00649596947644 ko05012 Parkinson's disease 1/325 155/7206 0.010279761215 ko04722 Neurotrophin signaling pathway 1/325 160/7206 0.0105591242662 ko04145 Phagosome 1/325 162/7206 0.010833487189 ko04060 Cytokine-cytokine receptor interaction 2/325 191/7206 0.0125040665545 ko04270 Vascular smooth muscle contraction 1/325 154/7206 0.015871821914 ko04022 cGMP-PKG signaling pathway 3/325 216/7206 0.0188666155347 ko04726 Serotonergic synapse 1/325 137/7206 0.021492296762 ko04261 Adrenergic signaling in cardiomyocytes 3/325 205/7206 0.0259964275228 ko04921 Oxytocin signaling pathway 3/325 209/7206 0.0262334916441 ko05231 Choline metabolism in cancer 1/325 134/7206 0.0320021819204 ko04611 Platelet activation 2/325 163/7206 0.0347791327306 ko04140 Autophagy - animal 2/325 164/7206 0.0348399791127 ko04310 Wnt signaling pathway 14/325 181/7206 0.0439290493678 ko04750 Inflammatory mediator regulation of TRP channels 1/325 122/7206 0.0448722083792 ko05168 Herpes simplex infection 14/325 182/7206 0.0449399352766 ko04660 T cell receptor signaling pathway 1/325 124/7206 0.0455079456707 ko05160 Hepatitis C 2/325 153/7206 0.048570676331