ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 34/262 191/7206 4.92693738143e-15 ko05340 Primary immunodeficiency 15/262 30/7206 1.64256603023e-14 ko04650 Natural killer cell mediated cytotoxicity 21/262 97/7206 2.24259163866e-11 ko05140 Leishmaniasis 18/262 75/7206 1.02632510425e-10 ko04612 Antigen processing and presentation 18/262 77/7206 1.64387082072e-10 ko05330 Allograft rejection 11/262 24/7206 1.95649397534e-10 ko05164 Influenza A 26/262 167/7206 2.23959430803e-10 ko05145 Toxoplasmosis 22/262 126/7206 6.21226103315e-10 ko05162 Measles 21/262 120/7206 1.48527363509e-09 ko05320 Autoimmune thyroid disease 11/262 29/7206 2.30566537255e-09 ko05152 Tuberculosis 26/262 187/7206 2.78489674972e-09 ko05332 Graft-versus-host disease 9/262 18/7206 3.5364221329e-09 ko04659 Th17 cell differentiation 19/262 106/7206 6.11098856165e-09 ko05168 Herpes simplex infection 25/262 182/7206 7.37878182082e-09 ko04672 Intestinal immune network for IgA production 11/262 37/7206 4.39624220294e-08 ko04380 Osteoclast differentiation 20/262 134/7206 6.1677071121e-08 ko05321 Inflammatory bowel disease (IBD) 13/262 56/7206 6.73231504996e-08 ko04621 NOD-like receptor signaling pathway 21/262 157/7206 1.97830818678e-07 ko05150 Staphylococcus aureus infection 10/262 36/7206 3.74831569885e-07 ko04062 Chemokine signaling pathway 23/262 201/7206 8.91609753604e-07 ko04940 Type I diabetes mellitus 9/262 32/7206 1.3027571647e-06 ko04145 Phagosome 20/262 162/7206 1.43491285868e-06 ko04658 Th1 and Th2 cell differentiation 15/262 96/7206 1.59961701973e-06 ko04064 NF-kappa B signaling pathway 15/262 96/7206 1.59961701973e-06 ko04217 Necroptosis 21/262 178/7206 1.64865016361e-06 ko04620 Toll-like receptor signaling pathway 15/262 100/7206 2.71840035519e-06 ko04630 Jak-STAT signaling pathway 17/262 132/7206 5.06267380904e-06 ko04660 T cell receptor signaling pathway 16/262 124/7206 9.42064875439e-06 ko05133 Pertussis 13/262 87/7206 1.32901896639e-05 ko04640 Hematopoietic cell lineage 11/262 64/7206 1.59689228347e-05 ko05310 Asthma 6/262 17/7206 1.92592988631e-05 ko03050 Proteasome 10/262 54/7206 1.97812515672e-05 ko05144 Malaria 9/262 45/7206 2.71762197783e-05 ko04662 B cell receptor signaling pathway 12/262 88/7206 7.2521772407e-05 ko05161 Hepatitis B 17/262 173/7206 0.000171255662185 ko05167 Kaposi's sarcoma-associated herpesvirus infection 18/262 191/7206 0.000188063970707 ko05323 Rheumatoid arthritis 11/262 89/7206 0.000350722418258 ko04622 RIG-I-like receptor signaling pathway 9/262 62/7206 0.000362363242851 ko05416 Viral myocarditis 8/262 55/7206 0.000757693278351 ko04666 Fc gamma R-mediated phagocytosis 12/262 122/7206 0.00153170618651 ko04610 Complement and coagulation cascades 9/262 79/7206 0.00214758665124 ko05142 Chagas disease (American trypanosomiasis) 12/262 130/7206 0.00263048739931 ko04514 Cell adhesion molecules (CAMs) 12/262 130/7206 0.00263048739931 ko04623 Cytosolic DNA-sensing pathway 6/262 41/7206 0.00336237485306 ko04360 Axon guidance 1/262 233/7206 0.00355078409223 ko00120 Primary bile acid biosynthesis 4/262 20/7206 0.00522176569533 ko04664 Fc epsilon RI signaling pathway 8/262 77/7206 0.00659042240727 ko05160 Hepatitis C 12/262 153/7206 0.0129034425386 ko04310 Wnt signaling pathway 1/262 181/7206 0.0150807283323 ko04611 Platelet activation 12/262 163/7206 0.017654043594 ko05224 Breast cancer 1/262 174/7206 0.0219848622004 ko04670 Leukocyte transendothelial migration 11/262 151/7206 0.0249082505092 ko05132 Salmonella infection 8/262 98/7206 0.0257707040833 ko05143 African trypanosomiasis 4/262 32/7206 0.0275923483123 ko04550 Signaling pathways regulating pluripotency of stem cells 1/262 165/7206 0.0320718769125 ko05010 Alzheimer's disease 2/262 202/7206 0.0350913851312 ko00590 Arachidonic acid metabolism 5/262 52/7206 0.0396019255738 ko04210 Apoptosis 12/262 180/7206 0.040108186437 ko04080 Neuroactive ligand-receptor interaction 8/262 423/7206 0.0446450377384 ko04724 Glutamatergic synapse 1/262 152/7206 0.0455353308417 ko04024 cAMP signaling pathway 4/262 279/7206 0.0480261968038