ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	100/656	423/7206	2.13852367092e-20
ko05033	Nicotine addiction	28/656	56/7206	2.73506061297e-15
ko04724	Glutamatergic synapse	42/656	152/7206	2.14008939206e-11
ko04974	Protein digestion and absorption	32/656	96/7206	2.57834837798e-11
ko04713	Circadian entrainment	35/656	136/7206	8.2069990476e-09
ko04728	Dopaminergic synapse	42/656	185/7206	1.50827360065e-08
ko04727	GABAergic synapse	30/656	110/7206	2.32086393945e-08
ko04976	Bile secretion	24/656	80/7206	8.29047112531e-08
ko04978	Mineral absorption	16/656	40/7206	1.45605695631e-07
ko05032	Morphine addiction	27/656	110/7206	1.17875472456e-06
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	22/656	79/7206	1.19221283508e-06
ko05014	Amyotrophic lateral sclerosis (ALS)	21/656	74/7206	1.48615575429e-06
ko04725	Cholinergic synapse	34/656	160/7206	2.05247848412e-06
ko04261	Adrenergic signaling in cardiomyocytes	40/656	205/7206	2.90155749575e-06
ko04911	Insulin secretion	27/656	117/7206	4.22421581624e-06
ko04742	Taste transduction	18/656	61/7206	4.53145392438e-06
ko04060	Cytokine-cytokine receptor interaction	2/656	191/7206	4.55079424279e-06
ko04512	ECM-receptor interaction	21/656	79/7206	4.71750454331e-06
ko04260	Cardiac muscle contraction	24/656	98/7206	4.82172157409e-06
ko05410	Hypertrophic cardiomyopathy (HCM)	24/656	100/7206	7.02562152854e-06
ko04921	Oxytocin signaling pathway	39/656	209/7206	1.25770089444e-05
ko04723	Retrograde endocannabinoid signaling	34/656	175/7206	2.28073019612e-05
ko04964	Proximal tubule bicarbonate reclamation	11/656	29/7206	2.45446129551e-05
ko03040	Spliceosome	1/656	145/7206	2.64738325689e-05
ko05164	Influenza A	2/656	167/7206	2.9737838286e-05
ko05031	Amphetamine addiction	21/656	91/7206	4.89897490372e-05
ko04721	Synaptic vesicle cycle	19/656	80/7206	7.33695897788e-05
ko04740	Olfactory transduction	19/656	80/7206	7.33695897788e-05
ko04970	Salivary secretion	21/656	95/7206	9.55958333633e-05
ko04514	Cell adhesion molecules (CAMs)	26/656	130/7206	0.000141486486494
ko03013	RNA transport	3/656	166/7206	0.000182133311602
ko04150	mTOR signaling pathway	4/656	184/7206	0.000224145056258
ko05030	Cocaine addiction	17/656	73/7206	0.000224726995215
ko04140	Autophagy - animal	3/656	164/7206	0.000271102398482
ko05162	Measles	1/656	120/7206	0.000292864181397
ko05168	Herpes simplex infection	4/656	182/7206	0.000333462422813
ko04120	Ubiquitin mediated proteolysis	2/656	138/7206	0.000437689273513
ko05161	Hepatitis B	4/656	173/7206	0.000448077600965
ko05166	HTLV-I infection	11/656	292/7206	0.000546672334171
ko05203	Viral carcinogenesis	10/656	277/7206	0.00057334770468
ko04024	cAMP signaling pathway	43/656	279/7206	0.000595925899263
ko04614	Renin-angiotensin system	7/656	18/7206	0.000652626297377
ko05414	Dilated cardiomyopathy	22/656	112/7206	0.000659090666767
ko04924	Renin secretion	18/656	86/7206	0.000860040183783
ko04932	Non-alcoholic fatty liver disease (NAFLD)	5/656	182/7206	0.000977827499891
ko04110	Cell cycle	3/656	145/7206	0.00110670098441
ko04726	Serotonergic synapse	24/656	137/7206	0.00145696238515
ko04010	MAPK signaling pathway	46/656	321/7206	0.00192907838171
ko04730	Long-term depression	16/656	78/7206	0.00205206896388
ko00350	Tyrosine metabolism	9/656	33/7206	0.00212331815791
ko04020	Calcium signaling pathway	39/656	265/7206	0.00221142434736
ko04142	Lysosome	4/656	151/7206	0.00245223588855
ko04972	Pancreatic secretion	20/656	111/7206	0.00247635396671
ko04141	Protein processing in endoplasmic reticulum	6/656	184/7206	0.00266349233115
ko04630	Jak-STAT signaling pathway	3/656	132/7206	0.00318857220006
ko04550	Signaling pathways regulating pluripotency of stem cells	5/656	165/7206	0.00362942136387
ko00830	Retinol metabolism	10/656	42/7206	0.00365810560741
ko04971	Gastric acid secretion	18/656	98/7206	0.00376847549248
ko00190	Oxidative phosphorylation	3/656	127/7206	0.00446421002702
ko05205	Proteoglycans in cancer	12/656	271/7206	0.00482862046661
ko04218	Cellular senescence	6/656	177/7206	0.00500269250934
ko04022	cGMP-PKG signaling pathway	32/656	216/7206	0.00538405490901
ko04914	Progesterone-mediated oocyte maturation	2/656	104/7206	0.00541004862544
ko00250	Alanine, aspartate and glutamate metabolism	9/656	38/7206	0.00594914696464
ko04137	Mitophagy - animal	1/656	82/7206	0.00611673482029
ko04138	Autophagy - yeast	1/656	81/7206	0.00611681487391
ko05152	Tuberculosis	7/656	187/7206	0.0065231600999
ko04621	NOD-like receptor signaling pathway	5/656	157/7206	0.00696030117267
ko04151	PI3K-Akt signaling pathway	51/656	390/7206	0.00835307839239
ko03008	Ribosome biogenesis in eukaryotes	1/656	79/7206	0.00911174704477
ko04144	Endocytosis	18/656	342/7206	0.00913299217069
ko05322	Systemic lupus erythematosus	5/656	151/7206	0.00931960331061
ko04217	Necroptosis	7/656	178/7206	0.0116813490134
ko04973	Carbohydrate digestion and absorption	9/656	42/7206	0.0117333467442
ko05215	Prostate cancer	3/656	111/7206	0.0121389809279
ko04214	Apoptosis - fly	1/656	72/7206	0.0130985914819
ko01521	EGFR tyrosine kinase inhibitor resistance	3/656	106/7206	0.0169428397966
ko04012	ErbB signaling pathway	3/656	109/7206	0.0172799733946
ko04961	Endocrine and other factor-regulated calcium reabsorption	11/656	59/7206	0.0195454979828
ko05016	Huntington's disease	10/656	215/7206	0.0212830216558
ko05220	Chronic myeloid leukemia	2/656	85/7206	0.0222721363361
ko05223	Non-small cell lung cancer	1/656	66/7206	0.0284823912564
ko04610	Complement and coagulation cascades	13/656	79/7206	0.0296974504193
ko05212	Pancreatic cancer	2/656	83/7206	0.0321661091058
ko00564	Glycerophospholipid metabolism	3/656	99/7206	0.0329203079959
ko00410	beta-Alanine metabolism	7/656	35/7206	0.0355133822236
ko04330	Notch signaling pathway	1/656	62/7206	0.0417976013652
ko04622	RIG-I-like receptor signaling pathway	1/656	62/7206	0.0417976013652
ko04977	Vitamin digestion and absorption	5/656	22/7206	0.0440399792697
ko00053	Ascorbate and aldarate metabolism	5/656	22/7206	0.0440399792697
ko04070	Phosphatidylinositol signaling system	4/656	112/7206	0.0445981987645
ko04664	Fc epsilon RI signaling pathway	2/656	77/7206	0.044598281013
ko05214	Glioma	2/656	79/7206	0.0457731152781
ko05211	Renal cell carcinoma	3/656	96/7206	0.0464370326482
ko04210	Apoptosis	9/656	180/7206	0.0493619182722
ko04720	Long-term potentiation	15/656	99/7206	0.0499325450252