ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	201/1205	423/7206	1.08652820214e-52
ko04724	Glutamatergic synapse	92/1205	152/7206	8.97044851221e-35
ko05033	Nicotine addiction	47/1205	56/7206	2.34770255366e-28
ko05032	Morphine addiction	67/1205	110/7206	8.75969576261e-26
ko04713	Circadian entrainment	76/1205	136/7206	1.04208371467e-25
ko04727	GABAergic synapse	66/1205	110/7206	7.01506518702e-25
ko04721	Synaptic vesicle cycle	51/1205	80/7206	3.51276875207e-21
ko04728	Dopaminergic synapse	85/1205	185/7206	4.92328436981e-21
ko04725	Cholinergic synapse	77/1205	160/7206	1.14274652024e-20
ko04024	cAMP signaling pathway	106/1205	279/7206	3.5423158547e-18
ko04723	Retrograde endocannabinoid signaling	77/1205	175/7206	8.70775898175e-18
ko04020	Calcium signaling pathway	100/1205	265/7206	5.58698269906e-17
ko04911	Insulin secretion	56/1205	117/7206	3.25378621212e-15
ko04742	Taste transduction	37/1205	61/7206	1.07979906913e-14
ko04726	Serotonergic synapse	61/1205	137/7206	1.26869086647e-14
ko04921	Oxytocin signaling pathway	79/1205	209/7206	1.09759814021e-13
ko04744	Phototransduction	26/1205	36/7206	2.31941404627e-13
ko05031	Amphetamine addiction	43/1205	91/7206	9.59860881166e-12
ko04720	Long-term potentiation	45/1205	99/7206	1.68118901661e-11
ko04970	Salivary secretion	43/1205	95/7206	5.656019983e-11
ko03040	Spliceosome	1/1205	145/7206	1.17091544508e-10
ko04261	Adrenergic signaling in cardiomyocytes	70/1205	205/7206	8.11097771016e-10
ko03010	Ribosome	1/1205	129/7206	2.57101803989e-09
ko04740	Olfactory transduction	35/1205	80/7206	1.05864943e-08
ko04925	Aldosterone synthesis and secretion	40/1205	105/7206	1.10057588083e-07
ko04971	Gastric acid secretion	38/1205	98/7206	1.42716129504e-07
ko05203	Viral carcinogenesis	17/1205	277/7206	1.5808509406e-07
ko04022	cGMP-PKG signaling pathway	66/1205	216/7206	3.70536315823e-07
ko05168	Herpes simplex infection	8/1205	182/7206	5.00780229417e-07
ko04060	Cytokine-cytokine receptor interaction	9/1205	191/7206	5.66025962497e-07
ko05030	Cocaine addiction	30/1205	73/7206	6.28119448926e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	30/1205	74/7206	8.89874892245e-07
ko05322	Systemic lupus erythematosus	6/1205	151/7206	2.27438775867e-06
ko04966	Collecting duct acid secretion	15/1205	26/7206	2.52987521895e-06
ko04360	Axon guidance	67/1205	233/7206	2.81079202209e-06
ko04621	NOD-like receptor signaling pathway	7/1205	157/7206	3.74667897591e-06
ko03013	RNA transport	8/1205	166/7206	4.21793440467e-06
ko04514	Cell adhesion molecules (CAMs)	42/1205	130/7206	1.28475327271e-05
ko05164	Influenza A	9/1205	167/7206	1.29735396646e-05
ko04972	Pancreatic secretion	37/1205	111/7206	1.54706519407e-05
ko04070	Phosphatidylinositol signaling system	37/1205	112/7206	1.83369703897e-05
ko04110	Cell cycle	7/1205	145/7206	2.30564641065e-05
ko04540	Gap junction	40/1205	128/7206	3.83228945969e-05
ko04730	Long-term depression	28/1205	78/7206	4.11717638113e-05
ko04010	MAPK signaling pathway	82/1205	321/7206	4.42831351686e-05
ko04072	Phospholipase D signaling pathway	55/1205	197/7206	6.17610872666e-05
ko04924	Renin secretion	29/1205	86/7206	0.000107804582692
ko03008	Ribosome biogenesis in eukaryotes	2/1205	79/7206	0.000110781638823
ko04141	Protein processing in endoplasmic reticulum	13/1205	184/7206	0.000129327333026
ko04014	Ras signaling pathway	71/1205	279/7206	0.000153635730543
ko04612	Antigen processing and presentation	2/1205	77/7206	0.000165619112214
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	27/1205	79/7206	0.000184423308304
ko04120	Ubiquitin mediated proteolysis	8/1205	138/7206	0.000187840251471
ko04745	Phototransduction - fly	16/1205	38/7206	0.000189803743658
ko05169	Epstein-Barr virus infection	16/1205	206/7206	0.000200488126093
ko05414	Dilated cardiomyopathy	34/1205	112/7206	0.000293764906245
ko05205	Proteoglycans in cancer	25/1205	271/7206	0.000457250575774
ko05110	Vibrio cholerae infection	22/1205	63/7206	0.000469789549535
ko04260	Cardiac muscle contraction	30/1205	98/7206	0.000559497473195
ko04923	Regulation of lipolysis in adipocytes	25/1205	77/7206	0.00059359923114
ko04610	Complement and coagulation cascades	3/1205	79/7206	0.000694589115885
ko04750	Inflammatory mediator regulation of TRP channels	35/1205	122/7206	0.000838530470857
ko04961	Endocrine and other factor-regulated calcium reabsorption	20/1205	59/7206	0.00121823458215
ko04976	Bile secretion	25/1205	80/7206	0.00127414575311
ko05161	Hepatitis B	14/1205	173/7206	0.0012858301383
ko04064	NF-kappa B signaling pathway	5/1205	96/7206	0.00129663777013
ko05140	Leishmaniasis	3/1205	75/7206	0.00151484117715
ko04330	Notch signaling pathway	2/1205	62/7206	0.00175986713572
ko05162	Measles	8/1205	120/7206	0.00182355960528
ko04930	Type II diabetes mellitus	18/1205	54/7206	0.00270138899999
ko04371	Apelin signaling pathway	45/1205	177/7206	0.00291905617243
ko04710	Circadian rhythm	15/1205	43/7206	0.00332622109808
ko04922	Glucagon signaling pathway	34/1205	128/7206	0.00401878681628
ko00604	Glycosphingolipid biosynthesis - ganglio series	7/1205	14/7206	0.00415043958664
ko04915	Estrogen signaling pathway	35/1205	131/7206	0.00420163647404
ko05144	Malaria	1/1205	45/7206	0.00433378643529
ko00071	Fatty acid degradation	1/1205	45/7206	0.00433378643529
ko03420	Nucleotide excision repair	1/1205	46/7206	0.0044560931938
ko04964	Proximal tubule bicarbonate reclamation	11/1205	29/7206	0.00506112140906
ko04626	Plant-pathogen interaction	8/1205	18/7206	0.00539249045537
ko00480	Glutathione metabolism	2/1205	55/7206	0.00564567024914
ko00240	Pyrimidine metabolism	8/1205	110/7206	0.00631702290646
ko05166	HTLV-I infection	32/1205	292/7206	0.00632769910048
ko04630	Jak-STAT signaling pathway	11/1205	132/7206	0.00663216592129
ko04214	Apoptosis - fly	4/1205	72/7206	0.00672558042973
ko05131	Shigellosis	5/1205	82/7206	0.00683790421613
ko03022	Basal transcription factors	1/1205	44/7206	0.00687337042412
ko00590	Arachidonic acid metabolism	2/1205	52/7206	0.00818247748414
ko04622	RIG-I-like receptor signaling pathway	3/1205	62/7206	0.00925772286975
ko04146	Peroxisome	6/1205	89/7206	0.00934817682148
ko04973	Carbohydrate digestion and absorption	14/1205	42/7206	0.0106518074897
ko04350	TGF-beta signaling pathway	8/1205	103/7206	0.0111835160371
ko04657	IL-17 signaling pathway	6/1205	87/7206	0.0129877492779
ko05133	Pertussis	6/1205	87/7206	0.0129877492779
ko00630	Glyoxylate and dicarboxylate metabolism	1/1205	38/7206	0.0147645201723
ko05145	Toxoplasmosis	11/1205	126/7206	0.0152898352433
ko05219	Bladder cancer	2/1205	48/7206	0.0178330910918
ko04115	p53 signaling pathway	5/1205	74/7206	0.0180805822481
ko05321	Inflammatory bowel disease (IBD)	3/1205	56/7206	0.0184619779393
ko05410	Hypertrophic cardiomyopathy (HCM)	26/1205	100/7206	0.0206689434655
ko04210	Apoptosis	19/1205	180/7206	0.0255263237269
ko00310	Lysine degradation	5/1205	73/7206	0.0256391101845
ko05016	Huntington's disease	24/1205	215/7206	0.0257287334357
ko04658	Th1 and Th2 cell differentiation	8/1205	96/7206	0.0266474352376
ko04912	GnRH signaling pathway	30/1205	122/7206	0.0266807323161
ko04640	Hematopoietic cell lineage	4/1205	64/7206	0.0267711046969
ko04270	Vascular smooth muscle contraction	36/1205	154/7206	0.0289912347424
ko00562	Inositol phosphate metabolism	23/1205	89/7206	0.0305813443204
ko05206	MicroRNAs in cancer	19/1205	177/7206	0.0317039889361
ko04217	Necroptosis	19/1205	178/7206	0.0320021679627
ko04015	Rap1 signaling pathway	60/1205	278/7206	0.0326925345582
ko03320	PPAR signaling pathway	5/1205	69/7206	0.0339588068605
ko00860	Porphyrin and chlorophyll metabolism	1/1205	34/7206	0.0342040081266
ko05231	Choline metabolism in cancer	32/1205	134/7206	0.0344614730273
ko04932	Non-alcoholic fatty liver disease (NAFLD)	20/1205	182/7206	0.0345334387611
ko05202	Transcriptional misregulation in cancer	21/1205	188/7206	0.0375249829384
ko03018	RNA degradation	7/1205	84/7206	0.0386641493212
ko05418	Fluid shear stress and atherosclerosis	19/1205	173/7206	0.039183797317
ko05132	Salmonella infection	9/1205	98/7206	0.0412478982248
ko05200	Pathways in cancer	66/1205	492/7206	0.0449789594151
ko00512	Mucin type O-glycan biosynthesis	9/1205	29/7206	0.0466657878225
ko05120	Epithelial cell signaling in Helicobacter pylori infection	23/1205	92/7206	0.0473601717308
ko04668	TNF signaling pathway	12/1205	120/7206	0.0479564006843