ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	202/1349	423/7206	5.44056382479e-45
ko04724	Glutamatergic synapse	91/1349	152/7206	7.07359344829e-30
ko05033	Nicotine addiction	48/1349	56/7206	1.74985391658e-27
ko05032	Morphine addiction	68/1349	110/7206	1.02551714242e-23
ko04727	GABAergic synapse	67/1349	110/7206	7.40116334167e-23
ko04713	Circadian entrainment	75/1349	136/7206	9.77052819378e-22
ko04728	Dopaminergic synapse	86/1349	185/7206	2.3039724633e-18
ko04721	Synaptic vesicle cycle	50/1349	80/7206	4.8237760039e-18
ko04725	Cholinergic synapse	75/1349	160/7206	2.08563744128e-16
ko04723	Retrograde endocannabinoid signaling	78/1349	175/7206	1.88843375159e-15
ko04020	Calcium signaling pathway	103/1349	265/7206	7.68900096021e-15
ko04024	cAMP signaling pathway	106/1349	279/7206	1.2748354841e-14
ko04726	Serotonergic synapse	62/1349	137/7206	9.92461424488e-13
ko04911	Insulin secretion	54/1349	117/7206	7.90440328809e-12
ko04742	Taste transduction	35/1349	61/7206	1.76050862157e-11
ko04921	Oxytocin signaling pathway	79/1349	209/7206	5.42557484929e-11
ko03010	Ribosome	1/1349	129/7206	1.24601327053e-10
ko04744	Phototransduction	24/1349	36/7206	3.51500759985e-10
ko05031	Amphetamine addiction	43/1349	91/7206	4.31629885089e-10
ko03040	Spliceosome	4/1349	145/7206	8.20628838239e-09
ko04970	Salivary secretion	42/1349	95/7206	1.09058247511e-08
ko05322	Systemic lupus erythematosus	5/1349	151/7206	1.78704497616e-08
ko04022	cGMP-PKG signaling pathway	74/1349	216/7206	3.85748183e-08
ko04261	Adrenergic signaling in cardiomyocytes	71/1349	205/7206	4.75811914279e-08
ko04720	Long-term potentiation	42/1349	99/7206	6.22165054144e-08
ko04925	Aldosterone synthesis and secretion	43/1349	105/7206	9.50964992129e-08
ko03013	RNA transport	8/1349	166/7206	1.73675842529e-07
ko04966	Collecting duct acid secretion	17/1349	26/7206	2.17979921896e-07
ko05030	Cocaine addiction	31/1349	73/7206	2.44530103901e-06
ko04971	Gastric acid secretion	38/1349	98/7206	2.82869982467e-06
ko05203	Viral carcinogenesis	24/1349	277/7206	2.94228125199e-06
ko04110	Cell cycle	8/1349	145/7206	7.12272207596e-06
ko04141	Protein processing in endoplasmic reticulum	13/1349	184/7206	8.39648651225e-06
ko05168	Herpes simplex infection	13/1349	182/7206	1.16949790427e-05
ko04070	Phosphatidylinositol signaling system	40/1349	112/7206	2.2176616703e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1349	79/7206	2.86191585793e-05
ko04010	MAPK signaling pathway	89/1349	321/7206	5.22907844163e-05
ko04745	Phototransduction - fly	18/1349	38/7206	5.26731640082e-05
ko04014	Ras signaling pathway	79/1349	279/7206	8.1103535087e-05
ko04730	Long-term depression	29/1349	78/7206	0.000108373182467
ko04072	Phospholipase D signaling pathway	59/1349	197/7206	0.000126407460204
ko04270	Vascular smooth muscle contraction	48/1349	154/7206	0.000153788508068
ko04750	Inflammatory mediator regulation of TRP channels	40/1349	122/7206	0.000231116572693
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1349	74/7206	0.000262949862095
ko04371	Apelin signaling pathway	53/1349	177/7206	0.000269473786598
ko00520	Amino sugar and nucleotide sugar metabolism	1/1349	55/7206	0.000335808133251
ko04915	Estrogen signaling pathway	41/1349	131/7206	0.000422751197755
ko04740	Olfactory transduction	28/1349	80/7206	0.000464672260432
ko04710	Circadian rhythm	18/1349	43/7206	0.000499781326691
ko04972	Pancreatic secretion	36/1349	111/7206	0.000503559697444
ko04922	Glucagon signaling pathway	40/1349	128/7206	0.000542582555384
ko04360	Axon guidance	64/1349	233/7206	0.00083453972101
ko04621	NOD-like receptor signaling pathway	14/1349	157/7206	0.000853045842758
ko04514	Cell adhesion molecules (CAMs)	40/1349	130/7206	0.000882215709402
ko05110	Vibrio cholerae infection	23/1349	63/7206	0.000892082540719
ko03420	Nucleotide excision repair	1/1349	46/7206	0.00178543006974
ko05205	Proteoglycans in cancer	32/1349	271/7206	0.00245897744398
ko04540	Gap junction	38/1349	128/7206	0.00269615710683
ko03022	Basal transcription factors	1/1349	44/7206	0.00275987837331
ko05169	Epstein-Barr virus infection	23/1349	206/7206	0.00363835876708
ko05161	Hepatitis B	18/1349	173/7206	0.00399150216074
ko04930	Type II diabetes mellitus	19/1349	54/7206	0.00424124390809
ko04923	Regulation of lipolysis in adipocytes	25/1349	77/7206	0.00463540584003
ko04924	Renin secretion	27/1349	86/7206	0.00486152681849
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1349	79/7206	0.00537149054345
ko05016	Huntington's disease	25/1349	215/7206	0.00576957206963
ko03410	Base excision repair	1/1349	38/7206	0.00591889210972
ko05131	Shigellosis	6/1349	82/7206	0.00621712536604
ko04964	Proximal tubule bicarbonate reclamation	12/1349	29/7206	0.00632620906649
ko05164	Influenza A	18/1349	167/7206	0.00650395532135
ko04064	NF-kappa B signaling pathway	8/1349	96/7206	0.00780369351469
ko05133	Pertussis	7/1349	87/7206	0.0081045173267
ko04622	RIG-I-like receptor signaling pathway	4/1349	62/7206	0.00868823416606
ko04626	Plant-pathogen interaction	8/1349	18/7206	0.0108636235374
ko05217	Basal cell carcinoma	5/1349	68/7206	0.0120854858285
ko04976	Bile secretion	24/1349	80/7206	0.0135992382461
ko00860	Porphyrin and chlorophyll metabolism	1/1349	34/7206	0.0136358594024
ko00562	Inositol phosphate metabolism	26/1349	89/7206	0.0137702846388
ko04120	Ubiquitin mediated proteolysis	15/1349	138/7206	0.0150908825392
ko04960	Aldosterone-regulated sodium reabsorption	14/1349	41/7206	0.0158068405927
ko04657	IL-17 signaling pathway	8/1349	87/7206	0.0185962833197
ko05414	Dilated cardiomyopathy	31/1349	112/7206	0.0196818172508
ko04214	Apoptosis - fly	6/1349	72/7206	0.0218532779237
ko05219	Bladder cancer	3/1349	48/7206	0.0245233442451
ko04962	Vasopressin-regulated water reabsorption	18/1349	58/7206	0.0260793789314
ko04612	Antigen processing and presentation	7/1349	77/7206	0.0271903202307
ko04113	Meiosis - yeast	6/1349	70/7206	0.0298439391975
ko05230	Central carbon metabolism in cancer	23/1349	81/7206	0.0310176029638
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1349	14/7206	0.0324934126695
ko05231	Choline metabolism in cancer	35/1349	134/7206	0.0330740333192
ko03018	RNA degradation	8/1349	84/7206	0.0335008313001
ko04015	Rap1 signaling pathway	66/1349	278/7206	0.0339340441079
ko00280	Valine, leucine and isoleucine degradation	4/1349	54/7206	0.0339703147062
ko00630	Glyoxylate and dicarboxylate metabolism	2/1349	38/7206	0.034615683962
ko05144	Malaria	3/1349	45/7206	0.0346677341826
ko00240	Pyrimidine metabolism	12/1349	110/7206	0.0355802454654
ko05140	Leishmaniasis	7/1349	75/7206	0.0364555140578
ko05202	Transcriptional misregulation in cancer	24/1349	188/7206	0.036619652194
ko04350	TGF-beta signaling pathway	11/1349	103/7206	0.0406333077162
ko04210	Apoptosis	23/1349	180/7206	0.0416115175789
ko04062	Chemokine signaling pathway	49/1349	201/7206	0.0432274656349
ko05162	Measles	14/1349	120/7206	0.04490180231
ko03015	mRNA surveillance pathway	10/1349	93/7206	0.0452013807844
ko04060	Cytokine-cytokine receptor interaction	25/1349	191/7206	0.0477924907752
ko04973	Carbohydrate digestion and absorption	13/1349	42/7206	0.0478486190837
ko04115	p53 signaling pathway	7/1349	74/7206	0.0496971029769
ko05145	Toxoplasmosis	15/1349	126/7206	0.04977466718