ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	147/893	423/7206	3.32392119336e-35
ko04724	Glutamatergic synapse	81/893	152/7206	6.95579663642e-35
ko05033	Nicotine addiction	41/893	56/7206	7.42633723266e-26
ko05032	Morphine addiction	57/893	110/7206	5.72952007721e-24
ko04727	GABAergic synapse	56/893	110/7206	4.54705762902e-23
ko04713	Circadian entrainment	63/893	136/7206	5.80480314824e-23
ko04728	Dopaminergic synapse	74/893	185/7206	5.24745801783e-22
ko04024	cAMP signaling pathway	89/893	279/7206	1.72636241884e-18
ko04725	Cholinergic synapse	63/893	160/7206	1.83473194442e-18
ko04723	Retrograde endocannabinoid signaling	66/893	175/7206	3.93035485563e-18
ko04020	Calcium signaling pathway	78/893	265/7206	4.96083655994e-14
ko04911	Insulin secretion	46/893	117/7206	9.12679967473e-14
ko04721	Synaptic vesicle cycle	36/893	80/7206	3.77329785782e-13
ko04921	Oxytocin signaling pathway	64/893	209/7206	1.81235569564e-12
ko04726	Serotonergic synapse	48/893	137/7206	4.01358197809e-12
ko04261	Adrenergic signaling in cardiomyocytes	60/893	205/7206	8.40279387361e-11
ko05031	Amphetamine addiction	35/893	91/7206	1.81511004711e-10
ko04742	Taste transduction	27/893	61/7206	5.47073831152e-10
ko04720	Long-term potentiation	36/893	99/7206	6.28318625797e-10
ko04744	Phototransduction	19/893	36/7206	5.32387824439e-09
ko05030	Cocaine addiction	27/893	73/7206	5.88653336914e-08
ko04072	Phospholipase D signaling pathway	51/893	197/7206	1.44655135301e-07
ko04925	Aldosterone synthesis and secretion	33/893	105/7206	1.9343324824e-07
ko04070	Phosphatidylinositol signaling system	34/893	112/7206	3.20379226963e-07
ko04010	MAPK signaling pathway	71/893	321/7206	5.76761320614e-07
ko04970	Salivary secretion	30/893	95/7206	6.19593807181e-07
ko03010	Ribosome	1/893	129/7206	1.12208065353e-06
ko03040	Spliceosome	2/893	145/7206	1.42118285164e-06
ko04972	Pancreatic secretion	32/893	111/7206	2.87869998261e-06
ko04730	Long-term depression	24/893	78/7206	1.34627750973e-05
ko05014	Amyotrophic lateral sclerosis (ALS)	23/893	74/7206	1.68933776434e-05
ko04022	cGMP-PKG signaling pathway	49/893	216/7206	2.05565676918e-05
ko04971	Gastric acid secretion	27/893	98/7206	3.92616656943e-05
ko04514	Cell adhesion molecules (CAMs)	33/893	130/7206	3.92704543775e-05
ko04360	Axon guidance	51/893	233/7206	4.18633388433e-05
ko04915	Estrogen signaling pathway	33/893	131/7206	4.47640536354e-05
ko04110	Cell cycle	4/893	145/7206	6.09924717211e-05
ko03013	RNA transport	6/893	166/7206	0.000116624841622
ko04060	Cytokine-cytokine receptor interaction	8/893	191/7206	0.00013279934664
ko04260	Cardiac muscle contraction	26/893	98/7206	0.00013507543818
ko05322	Systemic lupus erythematosus	5/893	151/7206	0.000147216264969
ko04930	Type II diabetes mellitus	17/893	54/7206	0.000176635937315
ko04014	Ras signaling pathway	56/893	279/7206	0.000189679079201
ko05203	Viral carcinogenesis	16/893	277/7206	0.000267577104696
ko04621	NOD-like receptor signaling pathway	6/893	157/7206	0.000323011654893
ko04750	Inflammatory mediator regulation of TRP channels	29/893	122/7206	0.000427673210352
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	21/893	79/7206	0.0004804432164
ko05414	Dilated cardiomyopathy	27/893	112/7206	0.000689939560345
ko04612	Antigen processing and presentation	1/893	77/7206	0.000737137313048
ko03008	Ribosome biogenesis in eukaryotes	1/893	79/7206	0.000788018064436
ko05168	Herpes simplex infection	9/893	182/7206	0.000889003189313
ko04141	Protein processing in endoplasmic reticulum	9/893	184/7206	0.000898946992288
ko04745	Phototransduction - fly	12/893	38/7206	0.00151696361332
ko04710	Circadian rhythm	13/893	43/7206	0.00153140170741
ko00562	Inositol phosphate metabolism	22/893	89/7206	0.00165342886135
ko04964	Proximal tubule bicarbonate reclamation	10/893	29/7206	0.00176872846007
ko04960	Aldosterone-regulated sodium reabsorption	12/893	41/7206	0.00311414702493
ko04973	Carbohydrate digestion and absorption	12/893	42/7206	0.00387891196974
ko05164	Influenza A	9/893	167/7206	0.00400111119324
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/893	14/7206	0.00442468252011
ko04924	Renin secretion	20/893	86/7206	0.00449696300357
ko05231	Choline metabolism in cancer	28/893	134/7206	0.00497274150662
ko04350	TGF-beta signaling pathway	4/893	103/7206	0.00596276193614
ko04015	Rap1 signaling pathway	49/893	278/7206	0.00918936464491
ko04540	Gap junction	26/893	128/7206	0.00958638416586
ko04966	Collecting duct acid secretion	8/893	26/7206	0.0108448603665
ko05110	Vibrio cholerae infection	15/893	63/7206	0.0109663099725
ko04071	Sphingolipid signaling pathway	31/893	162/7206	0.0112359863145
ko04064	NF-kappa B signaling pathway	4/893	96/7206	0.0114956909371
ko04918	Thyroid hormone synthesis	19/893	86/7206	0.0120844366777
ko05169	Epstein-Barr virus infection	14/893	206/7206	0.0130477786507
ko05410	Hypertrophic cardiomyopathy (HCM)	21/893	100/7206	0.0135431930738
ko04923	Regulation of lipolysis in adipocytes	17/893	77/7206	0.014310409303
ko04371	Apelin signaling pathway	33/893	177/7206	0.0147963106661
ko04610	Complement and coagulation cascades	3/893	79/7206	0.0152671633967
ko05200	Pathways in cancer	44/893	492/7206	0.0157618558743
ko04711	Circadian rhythm - fly	5/893	13/7206	0.0158108351087
ko04120	Ubiquitin mediated proteolysis	8/893	138/7206	0.0178600285237
ko04666	Fc gamma R-mediated phagocytosis	24/893	122/7206	0.0181884746925
ko04217	Necroptosis	12/893	178/7206	0.0204893186399
ko05140	Leishmaniasis	3/893	75/7206	0.021353008287
ko05133	Pertussis	4/893	87/7206	0.0214577886998
ko05130	Pathogenic Escherichia coli infection	3/893	77/7206	0.0219090291004
ko04740	Olfactory transduction	17/893	80/7206	0.0246083777168
ko04976	Bile secretion	17/893	80/7206	0.0246083777168
ko05162	Measles	7/893	120/7206	0.0248534878481
ko00260	Glycine, serine and threonine metabolism	1/893	48/7206	0.0255444837499
ko05034	Alcoholism	41/893	238/7206	0.0271986066603
ko00330	Arginine and proline metabolism	2/893	61/7206	0.0293642554089
ko04912	GnRH signaling pathway	23/893	122/7206	0.0366557236695
ko03022	Basal transcription factors	1/893	44/7206	0.0371647525769
ko00071	Fatty acid degradation	1/893	45/7206	0.0377789988328
ko04722	Neurotrophin signaling pathway	29/893	160/7206	0.0379292151229
ko04062	Chemokine signaling pathway	35/893	201/7206	0.0381947919774
ko04012	ErbB signaling pathway	21/893	109/7206	0.0386768108631
ko05010	Alzheimer's disease	35/893	202/7206	0.0388089194161
ko03420	Nucleotide excision repair	1/893	46/7206	0.0389979267614
ko05321	Inflammatory bowel disease (IBD)	2/893	56/7206	0.0409499906152
ko05217	Basal cell carcinoma	3/893	68/7206	0.0415131062248
ko03320	PPAR signaling pathway	3/893	69/7206	0.0417425185553
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/893	59/7206	0.0435295740571
ko04213	Longevity regulating pathway - multiple species	17/893	86/7206	0.0465963549194