ko pathway ratio_in_study ratio_in_pop p_value ko04744 Phototransduction 23/282 36/7206 2.56288289586e-24 ko04724 Glutamatergic synapse 32/282 152/7206 1.85091314314e-15 ko04727 GABAergic synapse 26/282 110/7206 5.07794110479e-14 ko05033 Nicotine addiction 19/282 56/7206 1.14453633215e-13 ko04723 Retrograde endocannabinoid signaling 30/282 175/7206 4.34086523822e-12 ko04080 Neuroactive ligand-receptor interaction 48/282 423/7206 1.0192541728e-11 ko05032 Morphine addiction 23/282 110/7206 2.37508109145e-11 ko04728 Dopaminergic synapse 27/282 185/7206 2.3163689731e-09 ko04740 Olfactory transduction 17/282 80/7206 8.02747385695e-09 ko04713 Circadian entrainment 22/282 136/7206 1.10201360208e-08 ko04725 Cholinergic synapse 22/282 160/7206 2.22950621013e-07 ko04742 Taste transduction 12/282 61/7206 3.19309389136e-06 ko04921 Oxytocin signaling pathway 23/282 209/7206 6.20528654755e-06 ko04024 cAMP signaling pathway 27/282 279/7206 1.09587270324e-05 ko04261 Adrenergic signaling in cardiomyocytes 21/282 205/7206 4.70026649553e-05 ko04726 Serotonergic synapse 16/282 137/7206 8.14316807981e-05 ko05030 Cocaine addiction 11/282 73/7206 0.000110982048805 ko04911 Insulin secretion 14/282 117/7206 0.000174912119525 ko05031 Amphetamine addiction 12/282 91/7206 0.000202506331202 ko04721 Synaptic vesicle cycle 11/282 80/7206 0.000256233911456 ko05414 Dilated cardiomyopathy 13/282 112/7206 0.000401971635135 ko04260 Cardiac muscle contraction 12/282 98/7206 0.000408500304849 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 10/282 79/7206 0.000947404816311 ko04010 MAPK signaling pathway 25/282 321/7206 0.00095594104459 ko05205 Proteoglycans in cancer 2/282 271/7206 0.00215216676599 ko04720 Long-term potentiation 10/282 99/7206 0.0051611714522 ko05410 Hypertrophic cardiomyopathy (HCM) 10/282 100/7206 0.00554208623242 ko04510 Focal adhesion 2/282 240/7206 0.00625880323412 ko05014 Amyotrophic lateral sclerosis (ALS) 8/282 74/7206 0.00798769504887 ko04062 Chemokine signaling pathway 16/282 201/7206 0.00807133156922 ko04141 Protein processing in endoplasmic reticulum 1/282 184/7206 0.0106287076601 ko04730 Long-term depression 8/282 78/7206 0.0108709230234 ko04976 Bile secretion 8/282 80/7206 0.0125718756159 ko04915 Estrogen signaling pathway 11/282 131/7206 0.0184786546532 ko04925 Aldosterone synthesis and secretion 9/282 105/7206 0.021395754749 ko04145 Phagosome 1/282 162/7206 0.02195336453 ko03013 RNA transport 1/282 166/7206 0.0227447110125 ko00830 Retinol metabolism 5/282 42/7206 0.0230590023405 ko04142 Lysosome 1/282 151/7206 0.0315027989442 ko05322 Systemic lupus erythematosus 1/282 151/7206 0.0315027989442 ko04970 Salivary secretion 8/282 95/7206 0.0320342284931 ko04621 NOD-like receptor signaling pathway 1/282 157/7206 0.0332275940485 ko05152 Tuberculosis 2/282 187/7206 0.0350102701047 ko04060 Cytokine-cytokine receptor interaction 2/282 191/7206 0.0353082715723 ko04072 Phospholipase D signaling pathway 14/282 197/7206 0.0369447736186 ko04120 Ubiquitin mediated proteolysis 1/282 138/7206 0.0449358930032 ko04218 Cellular senescence 2/282 177/7206 0.0489009790065 ko04217 Necroptosis 2/282 178/7206 0.0489541568648 ko05168 Herpes simplex infection 2/282 182/7206 0.0496878730212 ko04020 Calcium signaling pathway 17/282 265/7206 0.0498553695499