ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	146/773	423/7206	2.46336454923e-42
ko05033	Nicotine addiction	41/773	56/7206	2.27304145329e-28
ko04724	Glutamatergic synapse	65/773	152/7206	7.59814413517e-25
ko04721	Synaptic vesicle cycle	41/773	80/7206	1.17280755005e-19
ko04728	Dopaminergic synapse	64/773	185/7206	1.17273182213e-18
ko04727	GABAergic synapse	46/773	110/7206	2.04857404421e-17
ko05032	Morphine addiction	46/773	110/7206	2.04857404421e-17
ko04713	Circadian entrainment	49/773	136/7206	2.42736327521e-15
ko04723	Retrograde endocannabinoid signaling	56/773	175/7206	9.40770134521e-15
ko04725	Cholinergic synapse	49/773	160/7206	2.98865168906e-12
ko04024	cAMP signaling pathway	70/773	279/7206	3.41638761789e-12
ko04911	Insulin secretion	40/773	117/7206	6.63417987651e-12
ko04726	Serotonergic synapse	42/773	137/7206	1.07782593374e-10
ko05031	Amphetamine addiction	32/773	91/7206	3.85491044984e-10
ko04742	Taste transduction	25/773	61/7206	8.04752050403e-10
ko05030	Cocaine addiction	24/773	73/7206	2.65686862625e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/773	74/7206	3.54020731184e-07
ko04261	Adrenergic signaling in cardiomyocytes	46/773	205/7206	8.38744542857e-07
ko04720	Long-term potentiation	28/773	99/7206	9.22140900169e-07
ko04514	Cell adhesion molecules (CAMs)	33/773	130/7206	1.84780459813e-06
ko04921	Oxytocin signaling pathway	46/773	209/7206	1.93968713131e-06
ko03040	Spliceosome	1/773	145/7206	2.02828868645e-06
ko04120	Ubiquitin mediated proteolysis	1/773	138/7206	4.60240149223e-06
ko04020	Calcium signaling pathway	53/773	265/7206	6.13330115166e-06
ko05164	Influenza A	3/773	167/7206	1.21663639286e-05
ko05168	Herpes simplex infection	4/773	182/7206	1.62583671869e-05
ko04740	Olfactory transduction	22/773	80/7206	2.19922323571e-05
ko04060	Cytokine-cytokine receptor interaction	5/773	191/7206	4.15783623701e-05
ko04010	MAPK signaling pathway	58/773	321/7206	6.09412314313e-05
ko04970	Salivary secretion	24/773	95/7206	6.30739918917e-05
ko04360	Axon guidance	44/773	233/7206	0.000144872785176
ko05203	Viral carcinogenesis	12/773	277/7206	0.000149233712777
ko04730	Long-term depression	20/773	78/7206	0.00014994328032
ko04966	Collecting duct acid secretion	10/773	26/7206	0.00020310007707
ko04621	NOD-like receptor signaling pathway	4/773	157/7206	0.000204806190672
ko04744	Phototransduction	12/773	36/7206	0.000232647760696
ko03013	RNA transport	5/773	166/7206	0.000327309616377
ko04540	Gap junction	27/773	128/7206	0.000459535647699
ko04971	Gastric acid secretion	22/773	98/7206	0.000731015168766
ko04972	Pancreatic secretion	24/773	111/7206	0.000890262375397
ko05322	Systemic lupus erythematosus	5/773	151/7206	0.00125929222143
ko05162	Measles	3/773	120/7206	0.00147302530504
ko04260	Cardiac muscle contraction	21/773	98/7206	0.00156292514168
ko04925	Aldosterone synthesis and secretion	22/773	105/7206	0.00204971055614
ko04141	Protein processing in endoplasmic reticulum	8/773	184/7206	0.00244193297358
ko04610	Complement and coagulation cascades	1/773	79/7206	0.00272304151678
ko03008	Ribosome biogenesis in eukaryotes	1/773	79/7206	0.00272304151678
ko04932	Non-alcoholic fatty liver disease (NAFLD)	8/773	182/7206	0.00331099549911
ko00310	Lysine degradation	1/773	73/7206	0.00388062557086
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	17/773	79/7206	0.0049456030025
ko04745	Phototransduction - fly	10/773	38/7206	0.00549407297205
ko05110	Vibrio cholerae infection	14/773	63/7206	0.0066950529431
ko05205	Proteoglycans in cancer	16/773	271/7206	0.00673416457144
ko04022	cGMP-PKG signaling pathway	36/773	216/7206	0.00698185694401
ko03018	RNA degradation	2/773	84/7206	0.00726182837449
ko05169	Epstein-Barr virus infection	11/773	206/7206	0.00837281728735
ko01200	Carbon metabolism	5/773	128/7206	0.00879196995089
ko05166	HTLV-I infection	18/773	292/7206	0.00882752058353
ko04964	Proximal tubule bicarbonate reclamation	8/773	29/7206	0.00933445003825
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/773	59/7206	0.00968302627456
ko05034	Alcoholism	38/773	238/7206	0.010467110672
ko04140	Autophagy - animal	8/773	164/7206	0.0104677651651
ko00561	Glycerolipid metabolism	1/773	63/7206	0.0125080097342
ko04014	Ras signaling pathway	43/773	279/7206	0.0133218671167
ko01524	Platinum drug resistance	2/773	76/7206	0.0148889088804
ko04612	Antigen processing and presentation	2/773	77/7206	0.0149416899618
ko04630	Jak-STAT signaling pathway	6/773	132/7206	0.0156101135693
ko04668	TNF signaling pathway	5/773	120/7206	0.0163292353438
ko00330	Arginine and proline metabolism	1/773	61/7206	0.0192954476722
ko04146	Peroxisome	3/773	89/7206	0.0230922931965
ko00280	Valine, leucine and isoleucine degradation	1/773	54/7206	0.0265442333851
ko04916	Melanogenesis	24/773	142/7206	0.0269989312774
ko04976	Bile secretion	15/773	80/7206	0.0277138338223
ko04611	Platelet activation	9/773	163/7206	0.0287300386003
ko04064	NF-kappa B signaling pathway	4/773	96/7206	0.0308891885445
ko00564	Glycerophospholipid metabolism	4/773	99/7206	0.0315472941975
ko05146	Amoebiasis	4/773	99/7206	0.0315472941975
ko04924	Renin secretion	16/773	86/7206	0.0327936057251
ko05161	Hepatitis B	10/773	173/7206	0.0336183652628
ko04626	Plant-pathogen interaction	5/773	18/7206	0.0366675685272
ko00380	Tryptophan metabolism	1/773	50/7206	0.0387828027804
ko00590	Arachidonic acid metabolism	1/773	52/7206	0.0395223610646
ko04110	Cell cycle	8/773	145/7206	0.0410533993567
ko04640	Hematopoietic cell lineage	2/773	64/7206	0.042757081559
ko05016	Huntington's disease	14/773	215/7206	0.0434219565582
ko04974	Protein digestion and absorption	17/773	96/7206	0.0437413067821
ko04072	Phospholipase D signaling pathway	30/773	197/7206	0.0463607306364
ko04217	Necroptosis	11/773	178/7206	0.0489538099229