ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 26/228 191/7206 2.11933323416e-10 ko00643 Styrene degradation 4/228 4/7206 9.7686893632e-07 ko04621 NOD-like receptor signaling pathway 18/228 157/7206 1.97300051278e-06 ko04668 TNF signaling pathway 15/228 120/7206 4.96590936789e-06 ko00350 Tyrosine metabolism 8/228 33/7206 6.22323531511e-06 ko04380 Osteoclast differentiation 14/228 134/7206 7.93424671933e-05 ko04657 IL-17 signaling pathway 11/228 87/7206 8.40872220758e-05 ko05164 Influenza A 15/228 167/7206 0.000245499264648 ko04666 Fc gamma R-mediated phagocytosis 12/228 122/7206 0.000451513110369 ko04064 NF-kappa B signaling pathway 10/228 96/7206 0.000858685149889 ko04672 Intestinal immune network for IgA production 6/228 37/7206 0.000959266565801 ko05132 Salmonella infection 10/228 98/7206 0.00100906020705 ko05131 Shigellosis 9/228 82/7206 0.00106588052326 ko05133 Pertussis 9/228 87/7206 0.00162742641247 ko04623 Cytosolic DNA-sensing pathway 6/228 41/7206 0.00166975893521 ko05145 Toxoplasmosis 11/228 126/7206 0.00206971400035 ko05160 Hepatitis C 12/228 153/7206 0.00324504726476 ko04512 ECM-receptor interaction 8/228 79/7206 0.00334907894082 ko04611 Platelet activation 12/228 163/7206 0.00540848465689 ko04660 T cell receptor signaling pathway 10/228 124/7206 0.00576076888383 ko04810 Regulation of actin cytoskeleton 17/228 264/7206 0.00585558728129 ko05323 Rheumatoid arthritis 8/228 89/7206 0.00692711019185 ko05034 Alcoholism 1/228 238/7206 0.00727242271853 ko04210 Apoptosis 13/228 180/7206 0.00737542679668 ko04630 Jak-STAT signaling pathway 10/228 132/7206 0.00885462120877 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 2/228 5/7206 0.00935763566617 ko05418 Fluid shear stress and atherosclerosis 12/228 173/7206 0.0121775103747 ko04510 Focal adhesion 15/228 240/7206 0.0125174768801 ko04062 Chemokine signaling pathway 13/228 201/7206 0.0125577384527 ko04217 Necroptosis 12/228 178/7206 0.0136960547629 ko00360 Phenylalanine metabolism 3/228 17/7206 0.0153103229233 ko05016 Huntington's disease 1/228 215/7206 0.0154792861631 ko04662 B cell receptor signaling pathway 7/228 88/7206 0.0210021751186 ko00590 Arachidonic acid metabolism 5/228 52/7206 0.0235810309877 ko00740 Riboflavin metabolism 2/228 8/7206 0.0246078801465 ko04670 Leukocyte transendothelial migration 10/228 151/7206 0.0285922614094 ko05134 Legionellosis 6/228 74/7206 0.0291265509139 ko00626 Naphthalene degradation 1/228 1/7206 0.0316402997502 ko00401 Novobiocin biosynthesis 1/228 1/7206 0.0316402997502 ko04390 Hippo signaling pathway 1/228 188/7206 0.0318993482185 ko04974 Protein digestion and absorption 7/228 96/7206 0.0319681619865 ko04658 Th1 and Th2 cell differentiation 7/228 96/7206 0.0319681619865 ko00980 Metabolism of xenobiotics by cytochrome P450 4/228 40/7206 0.0366378763723 ko05146 Amoebiasis 7/228 99/7206 0.0369161206675 ko00950 Isoquinoline alkaloid biosynthesis 2/228 10/7206 0.0379388127691 ko04620 Toll-like receptor signaling pathway 7/228 100/7206 0.038671654087 ko00130 Ubiquinone and other terpenoid-quinone biosynthesis 2/228 11/7206 0.0454201195544 ko04622 RIG-I-like receptor signaling pathway 5/228 62/7206 0.0456756912158