ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 27/221 167/7206 6.87949169187e-13 ko04060 Cytokine-cytokine receptor interaction 28/221 191/7206 3.0069534596e-12 ko04658 Th1 and Th2 cell differentiation 17/221 96/7206 3.69891963316e-09 ko05162 Measles 18/221 120/7206 1.96206185624e-08 ko04380 Osteoclast differentiation 19/221 134/7206 2.01357461451e-08 ko04062 Chemokine signaling pathway 23/221 201/7206 4.00651239781e-08 ko05145 Toxoplasmosis 18/221 126/7206 4.28849122434e-08 ko04621 NOD-like receptor signaling pathway 20/221 157/7206 5.37318492938e-08 ko05140 Leishmaniasis 13/221 75/7206 3.51227977163e-07 ko05168 Herpes simplex infection 20/221 182/7206 6.25632503978e-07 ko04659 Th17 cell differentiation 15/221 106/7206 6.77928150494e-07 ko04660 T cell receptor signaling pathway 16/221 124/7206 1.02460049195e-06 ko04064 NF-kappa B signaling pathway 14/221 96/7206 1.11198705518e-06 ko05340 Primary immunodeficiency 8/221 30/7206 2.25379583019e-06 ko04650 Natural killer cell mediated cytotoxicity 13/221 97/7206 7.11550655883e-06 ko05152 Tuberculosis 18/221 187/7206 1.52491492329e-05 ko04623 Cytosolic DNA-sensing pathway 8/221 41/7206 2.74944542764e-05 ko04217 Necroptosis 17/221 178/7206 2.93258154646e-05 ko05321 Inflammatory bowel disease (IBD) 9/221 56/7206 4.40498084643e-05 ko04630 Jak-STAT signaling pathway 14/221 132/7206 4.78270577079e-05 ko05160 Hepatitis C 15/221 153/7206 6.45299498455e-05 ko04662 B cell receptor signaling pathway 11/221 88/7206 7.05527014167e-05 ko04612 Antigen processing and presentation 10/221 77/7206 0.000108964999656 ko04672 Intestinal immune network for IgA production 7/221 37/7206 0.000108986345731 ko05332 Graft-versus-host disease 5/221 18/7206 0.000160255541477 ko05167 Kaposi's sarcoma-associated herpesvirus infection 16/221 191/7206 0.000238947417922 ko05161 Hepatitis B 15/221 173/7206 0.000257427244561 ko04666 Fc gamma R-mediated phagocytosis 12/221 122/7206 0.000339966120895 ko04622 RIG-I-like receptor signaling pathway 8/221 62/7206 0.000559288325368 ko05330 Allograft rejection 5/221 24/7206 0.000684019536692 ko04620 Toll-like receptor signaling pathway 10/221 100/7206 0.000930278229505 ko04668 TNF signaling pathway 11/221 120/7206 0.0010836715938 ko03050 Proteasome 7/221 54/7206 0.00120490134678 ko05323 Rheumatoid arthritis 9/221 89/7206 0.00153959967176 ko05320 Autoimmune thyroid disease 5/221 29/7206 0.00168690098577 ko04940 Type I diabetes mellitus 5/221 32/7206 0.00265472696372 ko04145 Phagosome 12/221 162/7206 0.00401684152362 ko05150 Staphylococcus aureus infection 5/221 36/7206 0.00450011934459 ko04657 IL-17 signaling pathway 8/221 87/7206 0.00502497270013 ko05142 Chagas disease (American trypanosomiasis) 10/221 130/7206 0.00645546798439 ko00140 Steroid hormone biosynthesis 5/221 41/7206 0.00790481483397 ko00051 Fructose and mannose metabolism 5/221 42/7206 0.00875431690465 ko05034 Alcoholism 1/221 238/7206 0.0109734668525 ko05131 Shigellosis 7/221 82/7206 0.0125775107939 ko04210 Apoptosis 12/221 180/7206 0.0125898018562 ko04640 Hematopoietic cell lineage 6/221 64/7206 0.0132533544062 ko05016 Huntington's disease 1/221 215/7206 0.0151332263464 ko04917 Prolactin signaling pathway 7/221 87/7206 0.0170141817913 ko05133 Pertussis 7/221 87/7206 0.0170141817913 ko04611 Platelet activation 11/221 163/7206 0.0172426983566 ko04514 Cell adhesion molecules (CAMs) 9/221 130/7206 0.0181744169753 ko00590 Arachidonic acid metabolism 5/221 52/7206 0.0209206800303 ko04670 Leukocyte transendothelial migration 10/221 151/7206 0.0260626826127 ko05132 Salmonella infection 7/221 98/7206 0.0304525304588 ko00966 Glucosinolate biosynthesis 1/221 1/7206 0.0306688870386 ko04390 Hippo signaling pathway 1/221 188/7206 0.0315112468141 ko04610 Complement and coagulation cascades 6/221 79/7206 0.0337608924378