ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	159/822	423/7206	3.10050114382e-48
ko04724	Glutamatergic synapse	76/822	152/7206	8.24376338074e-33
ko05033	Nicotine addiction	43/822	56/7206	4.67076175731e-30
ko04727	GABAergic synapse	52/822	110/7206	2.76586360495e-21
ko05032	Morphine addiction	52/822	110/7206	2.76586360495e-21
ko04728	Dopaminergic synapse	69/822	185/7206	1.23940529783e-20
ko04713	Circadian entrainment	57/822	136/7206	4.66213786023e-20
ko04723	Retrograde endocannabinoid signaling	64/822	175/7206	1.08442746205e-18
ko04721	Synaptic vesicle cycle	40/822	80/7206	9.74628598897e-18
ko04725	Cholinergic synapse	57/822	160/7206	3.68018976665e-16
ko04024	cAMP signaling pathway	77/822	279/7206	2.75805668122e-14
ko04911	Insulin secretion	44/822	117/7206	1.0437101097e-13
ko04020	Calcium signaling pathway	73/822	265/7206	1.51251540296e-13
ko04726	Serotonergic synapse	46/822	137/7206	3.28858785815e-12
ko05031	Amphetamine addiction	35/822	91/7206	1.72420003008e-11
ko04970	Salivary secretion	34/822	95/7206	3.33857809965e-10
ko04742	Taste transduction	26/822	61/7206	5.05544033806e-10
ko04921	Oxytocin signaling pathway	56/822	209/7206	5.64969565149e-10
ko04720	Long-term potentiation	34/822	99/7206	1.18142027609e-09
ko05030	Cocaine addiction	27/822	73/7206	9.91720030401e-09
ko04261	Adrenergic signaling in cardiomyocytes	52/822	205/7206	1.70040308717e-08
ko04925	Aldosterone synthesis and secretion	32/822	105/7206	9.48785370948e-08
ko04971	Gastric acid secretion	29/822	98/7206	7.56075648752e-07
ko05014	Amyotrophic lateral sclerosis (ALS)	24/822	74/7206	1.10123215557e-06
ko04972	Pancreatic secretion	30/822	111/7206	5.26482694381e-06
ko05164	Influenza A	3/822	167/7206	5.56890487918e-06
ko03040	Spliceosome	2/822	145/7206	7.80151269679e-06
ko05162	Measles	1/822	120/7206	1.47895501294e-05
ko04514	Cell adhesion molecules (CAMs)	32/822	130/7206	1.83259291251e-05
ko05168	Herpes simplex infection	5/822	182/7206	2.72205267461e-05
ko04540	Gap junction	31/822	128/7206	3.34773345291e-05
ko04730	Long-term depression	22/822	78/7206	3.73369006996e-05
ko05203	Viral carcinogenesis	12/822	277/7206	4.27704015562e-05
ko04010	MAPK signaling pathway	60/822	321/7206	9.69568408641e-05
ko04120	Ubiquitin mediated proteolysis	3/822	138/7206	0.000111071196594
ko04022	cGMP-PKG signaling pathway	44/822	216/7206	0.000115326296021
ko05322	Systemic lupus erythematosus	4/822	151/7206	0.000136198923382
ko04630	Jak-STAT signaling pathway	3/822	132/7206	0.000156714976256
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/822	59/7206	0.000211680561533
ko04750	Inflammatory mediator regulation of TRP channels	28/822	122/7206	0.000246497451071
ko05205	Proteoglycans in cancer	14/822	271/7206	0.000423232580464
ko03013	RNA transport	6/822	166/7206	0.000476905215837
ko05110	Vibrio cholerae infection	17/822	63/7206	0.000497680511532
ko04072	Phospholipase D signaling pathway	39/822	197/7206	0.000557207144163
ko04260	Cardiac muscle contraction	23/822	98/7206	0.000602336478015
ko04060	Cytokine-cytokine receptor interaction	8/822	191/7206	0.000712011337529
ko04070	Phosphatidylinositol signaling system	25/822	112/7206	0.000807429342699
ko04621	NOD-like receptor signaling pathway	6/822	157/7206	0.00130405195094
ko04966	Collecting duct acid secretion	9/822	26/7206	0.00161587766273
ko04918	Thyroid hormone synthesis	20/822	86/7206	0.00165735494437
ko05169	Epstein-Barr virus infection	10/822	206/7206	0.00167112069532
ko04550	Signaling pathways regulating pluripotency of stem cells	7/822	165/7206	0.00177484080782
ko04915	Estrogen signaling pathway	27/822	131/7206	0.00199442556665
ko05166	HTLV-I infection	18/822	292/7206	0.00256872680492
ko04745	Phototransduction - fly	11/822	38/7206	0.00262172450247
ko04141	Protein processing in endoplasmic reticulum	9/822	184/7206	0.00308045048915
ko04110	Cell cycle	6/822	145/7206	0.00334117345671
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/822	79/7206	0.00360928095743
ko04510	Focal adhesion	14/822	240/7206	0.00373700603269
ko04964	Proximal tubule bicarbonate reclamation	9/822	29/7206	0.00378248022531
ko05220	Chronic myeloid leukemia	2/822	85/7206	0.00510078870464
ko04924	Renin secretion	19/822	86/7206	0.00529884993031
ko04962	Vasopressin-regulated water reabsorption	14/822	58/7206	0.00555840948378
ko04217	Necroptosis	9/822	178/7206	0.00558684380795
ko04744	Phototransduction	10/822	36/7206	0.0056130628873
ko05211	Renal cell carcinoma	3/822	96/7206	0.00563935498553
ko05215	Prostate cancer	4/822	111/7206	0.00611175246663
ko03008	Ribosome biogenesis in eukaryotes	2/822	79/7206	0.00706648886908
ko05161	Hepatitis B	9/822	173/7206	0.00729115922865
ko04932	Non-alcoholic fatty liver disease (NAFLD)	10/822	182/7206	0.00892320341547
ko04014	Ras signaling pathway	46/822	279/7206	0.0092294200901
ko05414	Dilated cardiomyopathy	22/822	112/7206	0.0100039560645
ko04612	Antigen processing and presentation	2/822	77/7206	0.0103346659358
ko05222	Small cell lung cancer	3/822	89/7206	0.0112195731962
ko04626	Plant-pathogen interaction	6/822	18/7206	0.0119990742773
ko00330	Arginine and proline metabolism	1/822	61/7206	0.0128881686346
ko04270	Vascular smooth muscle contraction	28/822	154/7206	0.0140190179134
ko00310	Lysine degradation	2/822	73/7206	0.0147049075483
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/822	14/7206	0.0158260929191
ko05200	Pathways in cancer	40/822	492/7206	0.0184470934114
ko04360	Axon guidance	38/822	233/7206	0.0208727589687
ko04740	Olfactory transduction	16/822	80/7206	0.0208908684212
ko04976	Bile secretion	16/822	80/7206	0.0208908684212
ko05212	Pancreatic cancer	3/822	83/7206	0.0223205571948
ko04064	NF-kappa B signaling pathway	4/822	96/7206	0.0223235557663
ko04668	TNF signaling pathway	6/822	120/7206	0.028268632158
ko04664	Fc epsilon RI signaling pathway	3/822	77/7206	0.0307190810939
ko04610	Complement and coagulation cascades	3/822	79/7206	0.0309623072599
ko04140	Autophagy - animal	10/822	164/7206	0.0334824633472
ko04620	Toll-like receptor signaling pathway	5/822	100/7206	0.0391697772408
ko04978	Mineral absorption	9/822	40/7206	0.0408209521732
ko04146	Peroxisome	4/822	89/7206	0.0419877619416
ko04330	Notch signaling pathway	2/822	62/7206	0.0424207211604
ko04115	p53 signaling pathway	3/822	74/7206	0.0425734771419
ko05140	Leishmaniasis	3/822	75/7206	0.0428228203774
ko01524	Platinum drug resistance	3/822	76/7206	0.0434308384368
ko04916	Melanogenesis	24/822	142/7206	0.0447429340852
ko04960	Aldosterone-regulated sodium reabsorption	9/822	41/7206	0.0451061047743
ko05120	Epithelial cell signaling in Helicobacter pylori infection	17/822	92/7206	0.0452039700217
ko04068	FoxO signaling pathway	11/822	167/7206	0.0481986669523
ko04930	Type II diabetes mellitus	11/822	54/7206	0.0499441505413