ko pathway ratio_in_study ratio_in_pop p_value ko03040 Spliceosome 47/341 145/7206 1.29049437236e-27 ko04110 Cell cycle 47/341 145/7206 1.29049437236e-27 ko04111 Cell cycle - yeast 37/341 90/7206 3.68335836792e-26 ko03030 DNA replication 24/341 38/7206 3.80425346854e-23 ko04113 Meiosis - yeast 26/341 70/7206 2.33666145895e-17 ko03013 RNA transport 38/341 166/7206 1.14899122626e-16 ko03460 Fanconi anemia pathway 20/341 51/7206 3.71434556982e-14 ko00240 Pyrimidine metabolism 27/341 110/7206 6.2877128517e-13 ko03430 Mismatch repair 13/341 22/7206 1.61284331408e-12 ko03440 Homologous recombination 16/341 41/7206 1.56428863175e-11 ko03420 Nucleotide excision repair 15/341 46/7206 1.32244714717e-09 ko03015 mRNA surveillance pathway 21/341 93/7206 1.33006830986e-09 ko03410 Base excision repair 12/341 38/7206 9.24983032166e-08 ko03008 Ribosome biogenesis in eukaryotes 17/341 79/7206 1.09735494814e-07 ko00230 Purine metabolism 27/341 194/7206 3.59132052072e-07 ko04114 Oocyte meiosis 19/341 139/7206 2.63391218211e-05 ko05205 Proteoglycans in cancer 1/341 271/7206 5.11741851437e-05 ko04810 Regulation of actin cytoskeleton 1/341 264/7206 7.76151018971e-05 ko04914 Progesterone-mediated oocyte maturation 15/341 104/7206 0.000100474432183 ko03018 RNA degradation 13/341 84/7206 0.000140772289832 ko04510 Focal adhesion 1/341 240/7206 0.000156871832671 ko04144 Endocytosis 4/341 342/7206 0.000368995034987 ko04010 MAPK signaling pathway 4/341 321/7206 0.00105041108329 ko04062 Chemokine signaling pathway 1/341 201/7206 0.00108121222162 ko05010 Alzheimer's disease 1/341 202/7206 0.00109057154634 ko04015 Rap1 signaling pathway 3/341 278/7206 0.00128797194819 ko04014 Ras signaling pathway 3/341 279/7206 0.00129840420941 ko04360 Axon guidance 2/341 233/7206 0.00148836635121 ko04060 Cytokine-cytokine receptor interaction 1/341 191/7206 0.00156875303656 ko00670 One carbon pool by folate 5/341 20/7206 0.00198239836784 ko03020 RNA polymerase 6/341 29/7206 0.00202246635644 ko04932 Non-alcoholic fatty liver disease (NAFLD) 1/341 182/7206 0.00228827182049 ko04115 p53 signaling pathway 10/341 74/7206 0.00237553480766 ko05152 Tuberculosis 1/341 187/7206 0.00237901193919 ko04151 PI3K-Akt signaling pathway 7/341 390/7206 0.00295999194244 ko04140 Autophagy - animal 1/341 164/7206 0.00485846099432 ko04261 Adrenergic signaling in cardiomyocytes 2/341 205/7206 0.00648980407891 ko04621 NOD-like receptor signaling pathway 1/341 157/7206 0.00705910049096 ko05166 HTLV-I infection 24/341 292/7206 0.00713702864794 ko04145 Phagosome 1/341 162/7206 0.00734874651363 ko04072 Phospholipase D signaling pathway 2/341 197/7206 0.00927914028031 ko04670 Leukocyte transendothelial migration 1/341 151/7206 0.0103612317284 ko05012 Parkinson's disease 1/341 155/7206 0.0108895368909 ko04728 Dopaminergic synapse 2/341 185/7206 0.0126441767286 ko04916 Melanogenesis 1/341 142/7206 0.0149422855679 ko04217 Necroptosis 2/341 178/7206 0.0181082454415 ko04550 Signaling pathways regulating pluripotency of stem cells 2/341 165/7206 0.024763059167 ko04666 Fc gamma R-mediated phagocytosis 1/341 122/7206 0.0308556300525 ko04211 Longevity regulating pathway 1/341 123/7206 0.0308766699364 ko03450 Non-homologous end-joining 3/341 15/7206 0.0312840699595 ko05167 Kaposi's sarcoma-associated herpesvirus infection 3/341 191/7206 0.0360794016859 ko04071 Sphingolipid signaling pathway 2/341 162/7206 0.0361898060514 ko00450 Selenocompound metabolism 3/341 16/7206 0.0371879995761 ko04120 Ubiquitin mediated proteolysis 12/341 138/7206 0.0392639663213 ko03050 Proteasome 6/341 54/7206 0.0410494806305 ko05200 Pathways in cancer 14/341 492/7206 0.0466160832832