ko pathway ratio_in_study ratio_in_pop p_value ko04512 ECM-receptor interaction 16/206 79/7206 4.90127134051e-10 ko04510 Focal adhesion 27/206 240/7206 7.20135991314e-10 ko05410 Hypertrophic cardiomyopathy (HCM) 16/206 100/7206 1.80003504436e-08 ko05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 11/206 79/7206 1.31217819284e-05 ko05414 Dilated cardiomyopathy 13/206 112/7206 1.63836894975e-05 ko05131 Shigellosis 11/206 82/7206 1.88613695321e-05 ko05100 Bacterial invasion of epithelial cells 11/206 99/7206 0.000111011917046 ko04666 Fc gamma R-mediated phagocytosis 12/206 122/7206 0.000177151010157 ko04974 Protein digestion and absorption 10/206 96/7206 0.000387624474437 ko05146 Amoebiasis 10/206 99/7206 0.000496993869713 ko04621 NOD-like receptor signaling pathway 13/206 157/7206 0.000528349870078 ko04668 TNF signaling pathway 11/206 120/7206 0.000605519694316 ko04380 Osteoclast differentiation 11/206 134/7206 0.00151388601225 ko04933 AGE-RAGE signaling pathway in diabetic complications 11/206 135/7206 0.00160774482759 ko00627 Aminobenzoate degradation 3/206 9/7206 0.00170274024456 ko00930 Caprolactam degradation 3/206 9/7206 0.00170274024456 ko05164 Influenza A 12/206 167/7206 0.00290713396993 ko05133 Pertussis 8/206 87/7206 0.00328341267197 ko04810 Regulation of actin cytoskeleton 16/206 264/7206 0.00397695517885 ko05416 Viral myocarditis 6/206 55/7206 0.0045795771271 ko05134 Legionellosis 7/206 74/7206 0.00501128394409 ko04623 Cytosolic DNA-sensing pathway 5/206 41/7206 0.00590083361901 ko00650 Butanoate metabolism 4/206 26/7206 0.00591785393239 ko05132 Salmonella infection 8/206 98/7206 0.006774824565 ko04611 Platelet activation 11/206 163/7206 0.00687454004309 ko01212 Fatty acid metabolism 6/206 60/7206 0.00703094362188 ko04610 Complement and coagulation cascades 7/206 79/7206 0.00716298292103 ko00281 Geraniol degradation 2/206 5/7206 0.00768279321636 ko00071 Fatty acid degradation 5/206 45/7206 0.00877567831001 ko04660 T cell receptor signaling pathway 9/206 124/7206 0.00890548540205 ko04670 Leukocyte transendothelial migration 10/206 151/7206 0.0110883241644 ko04151 PI3K-Akt signaling pathway 20/206 390/7206 0.0111579182732 ko04060 Cytokine-cytokine receptor interaction 12/206 191/7206 0.0120900056626 ko04662 B cell receptor signaling pathway 7/206 88/7206 0.0126597501857 ko04920 Adipocytokine signaling pathway 7/206 89/7206 0.0134177282272 ko05205 Proteoglycans in cancer 15/206 271/7206 0.0137172192522 ko00760 Nicotinate and nicotinamide metabolism 4/206 34/7206 0.015374991684 ko00680 Methane metabolism 4/206 34/7206 0.015374991684 ko04217 Necroptosis 11/206 178/7206 0.018245355457 ko05150 Staphylococcus aureus infection 4/206 36/7206 0.0186862362447 ko04210 Apoptosis 11/206 180/7206 0.0189698464562 ko04064 NF-kappa B signaling pathway 7/206 96/7206 0.0196595297456 ko05168 Herpes simplex infection 11/206 182/7206 0.0197739427606 ko04932 Non-alcoholic fatty liver disease (NAFLD) 11/206 182/7206 0.0197739427606 ko04260 Cardiac muscle contraction 7/206 98/7206 0.0217634658359 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/206 191/7206 0.0244094235839 ko05145 Toxoplasmosis 8/206 126/7206 0.0275825555752 ko04144 Endocytosis 17/206 342/7206 0.0282087088287 ko05418 Fluid shear stress and atherosclerosis 10/206 173/7206 0.0324843956882 ko04657 IL-17 signaling pathway 6/206 87/7206 0.0377968860614 ko00710 Carbon fixation in photosynthetic organisms 3/206 27/7206 0.0406804164987 ko05222 Small cell lung cancer 6/206 89/7206 0.0415314990808 ko05219 Bladder cancer 4/206 48/7206 0.0474698526279 ko05120 Epithelial cell signaling in Helicobacter pylori infection 6/206 92/7206 0.0475570637746