ko pathway ratio_in_study ratio_in_pop p_value ko04662 B cell receptor signaling pathway 6/32 88/7206 1.96150001882e-06 ko05222 Small cell lung cancer 6/32 89/7206 2.09675579188e-06 ko04658 Th1 and Th2 cell differentiation 6/32 96/7206 3.27284533741e-06 ko04151 PI3K-Akt signaling pathway 10/32 390/7206 4.2372173208e-06 ko05200 Pathways in cancer 11/32 492/7206 4.64986245192e-06 ko05161 Hepatitis B 7/32 173/7206 8.25478562971e-06 ko04660 T cell receptor signaling pathway 6/32 124/7206 1.44471484099e-05 ko05166 HTLV-I infection 8/32 292/7206 2.96860888864e-05 ko04659 Th17 cell differentiation 5/32 106/7206 9.19713815294e-05 ko04218 Cellular senescence 6/32 177/7206 0.00010748041878 ko05215 Prostate cancer 5/32 111/7206 0.000114504741335 ko05167 Kaposi's sarcoma-associated herpesvirus infection 6/32 191/7206 0.000163463134187 ko04668 TNF signaling pathway 5/32 120/7206 0.000165524647297 ko04015 Rap1 signaling pathway 7/32 278/7206 0.000173012556551 ko04014 Ras signaling pathway 7/32 279/7206 0.000176915501159 ko05145 Toxoplasmosis 5/32 126/7206 0.000208160264852 ko04380 Osteoclast differentiation 5/32 134/7206 0.000277504678138 ko04931 Insulin resistance 5/32 137/7206 0.000307599101085 ko04010 MAPK signaling pathway 7/32 321/7206 0.000418560935228 ko05131 Shigellosis 4/32 82/7206 0.000439510661583 ko04360 Axon guidance 6/32 233/7206 0.000479150013646 ko05220 Chronic myeloid leukemia 4/32 85/7206 0.000504070631681 ko04510 Focal adhesion 6/32 240/7206 0.000560916215817 ko04611 Platelet activation 5/32 163/7206 0.000683953377534 ko04623 Cytosolic DNA-sensing pathway 3/32 41/7206 0.000756252380226 ko04620 Toll-like receptor signaling pathway 4/32 100/7206 0.000931703965758 ko04210 Apoptosis 5/32 180/7206 0.00107108280419 ko04024 cAMP signaling pathway 6/32 279/7206 0.00123576820716 ko04022 cGMP-PKG signaling pathway 5/32 216/7206 0.00240264766194 ko04622 RIG-I-like receptor signaling pathway 3/32 62/7206 0.00251870929599 ko05221 Acute myeloid leukemia 3/32 63/7206 0.00263670499203 ko04933 AGE-RAGE signaling pathway in diabetic complications 4/32 135/7206 0.00282019341462 ko05160 Hepatitis C 4/32 153/7206 0.00442332917156 ko04512 ECM-receptor interaction 3/32 79/7206 0.00500423761433 ko04722 Neurotrophin signaling pathway 4/32 160/7206 0.00518544806215 ko05212 Pancreatic cancer 3/32 83/7206 0.00574499447746 ko05164 Influenza A 4/32 167/7206 0.00603161610733 ko05218 Melanoma 3/32 85/7206 0.006138798659 ko04920 Adipocytokine signaling pathway 3/32 89/7206 0.00697412320272 ko05206 MicroRNAs in cancer 4/32 177/7206 0.0073941122665 ko01523 Antifolate resistance 2/32 30/7206 0.00769093102971 ko04064 NF-kappa B signaling pathway 3/32 96/7206 0.00859230193264 ko04650 Natural killer cell mediated cytotoxicity 3/32 97/7206 0.00884000373356 ko00073 Cutin, suberine and wax biosynthesis 1/32 2/7206 0.00886238104845 ko05146 Amoebiasis 3/32 99/7206 0.00934797194527 ko05169 Epstein-Barr virus infection 4/32 206/7206 0.0124604301119 ko05162 Measles 3/32 120/7206 0.0157186557144 ko04211 Longevity regulating pathway 3/32 123/7206 0.0167866480139 ko05142 Chagas disease (American trypanosomiasis) 3/32 130/7206 0.0194348851306 ko04919 Thyroid hormone signaling pathway 3/32 143/7206 0.0249373349071 ko05321 Inflammatory bowel disease (IBD) 2/32 56/7206 0.0253476735633 ko04962 Vasopressin-regulated water reabsorption 2/32 58/7206 0.0270588196204 ko04810 Regulation of actin cytoskeleton 4/32 264/7206 0.0282743838351 ko04621 NOD-like receptor signaling pathway 3/32 157/7206 0.031715094918 ko05418 Fluid shear stress and atherosclerosis 3/32 173/7206 0.0405358395106 ko05224 Breast cancer 3/32 174/7206 0.0411247870906 ko05030 Cocaine addiction 2/32 73/7206 0.0412896956691 ko05140 Leishmaniasis 2/32 75/7206 0.0433619526423 ko04310 Wnt signaling pathway 3/32 181/7206 0.0453699494134 ko05130 Pathogenic Escherichia coli infection 2/32 77/7206 0.0454727256815 ko04370 VEGF signaling pathway 2/32 77/7206 0.0454727256815 ko04932 Non-alcoholic fatty liver disease (NAFLD) 3/32 182/7206 0.0459938108189 ko05214 Glioma 2/32 79/7206 0.0476212168234 ko05230 Central carbon metabolism in cancer 2/32 81/7206 0.0498066384376