ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko05033	Nicotine addiction	37/806	56/7206	1.55904773575e-22
ko04080	Neuroactive ligand-receptor interaction	117/806	423/7206	3.2704916407e-22
ko04724	Glutamatergic synapse	56/806	152/7206	4.79010954665e-17
ko04020	Calcium signaling pathway	76/806	265/7206	1.37480934642e-15
ko04713	Circadian entrainment	49/806	136/7206	1.29643780982e-14
ko05032	Morphine addiction	43/806	110/7206	2.00614622335e-14
ko04723	Retrograde endocannabinoid signaling	54/806	175/7206	8.80526218672e-13
ko04727	GABAergic synapse	40/806	110/7206	2.63775937239e-12
ko04728	Dopaminergic synapse	53/806	185/7206	3.52772911808e-11
ko04721	Synaptic vesicle cycle	31/806	80/7206	1.21708901166e-10
ko04024	cAMP signaling pathway	67/806	279/7206	6.58546623194e-10
ko04921	Oxytocin signaling pathway	55/806	209/7206	8.53228065323e-10
ko04360	Axon guidance	58/806	233/7206	2.08026079062e-09
ko04725	Cholinergic synapse	45/806	160/7206	2.13620945835e-09
ko04911	Insulin secretion	36/806	117/7206	6.63553399032e-09
ko04022	cGMP-PKG signaling pathway	53/806	216/7206	1.76907388404e-08
ko03040	Spliceosome	1/806	145/7206	8.49788489437e-07
ko04970	Salivary secretion	28/806	95/7206	8.59075945009e-07
ko05031	Amphetamine addiction	27/806	91/7206	1.1653057533e-06
ko04261	Adrenergic signaling in cardiomyocytes	47/806	205/7206	1.33604793197e-06
ko04720	Long-term potentiation	28/806	99/7206	2.14254678536e-06
ko04514	Cell adhesion molecules (CAMs)	33/806	130/7206	3.99231585651e-06
ko03010	Ribosome	1/806	129/7206	6.61879525242e-06
ko04010	MAPK signaling pathway	63/806	321/7206	6.9695384057e-06
ko04726	Serotonergic synapse	33/806	137/7206	1.41587451338e-05
ko05322	Systemic lupus erythematosus	3/806	151/7206	3.644892077e-05
ko03013	RNA transport	5/806	166/7206	0.000160349869181
ko05168	Herpes simplex infection	6/806	182/7206	0.000180136169215
ko05203	Viral carcinogenesis	13/806	277/7206	0.000192073864247
ko04014	Ras signaling pathway	52/806	279/7206	0.000200240700465
ko04070	Phosphatidylinositol signaling system	26/806	112/7206	0.000222817550747
ko04742	Taste transduction	17/806	61/7206	0.000259469109613
ko04730	Long-term depression	20/806	78/7206	0.000355834674995
ko04925	Aldosterone synthesis and secretion	24/806	105/7206	0.000494024420288
ko05014	Amyotrophic lateral sclerosis (ALS)	19/806	74/7206	0.000514689093673
ko04930	Type II diabetes mellitus	15/806	54/7206	0.000613328895279
ko04371	Apelin signaling pathway	35/806	177/7206	0.000643028469547
ko05164	Influenza A	6/806	167/7206	0.000680417678415
ko04972	Pancreatic secretion	24/806	111/7206	0.00123124564137
ko04072	Phospholipase D signaling pathway	37/806	197/7206	0.00125159646951
ko04924	Renin secretion	20/806	86/7206	0.00144599692382
ko04710	Circadian rhythm	12/806	43/7206	0.00202334071985
ko05030	Cocaine addiction	17/806	73/7206	0.00252062459486
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/806	14/7206	0.00261362716973
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	18/806	79/7206	0.00319550621569
ko05414	Dilated cardiomyopathy	23/806	112/7206	0.0035689363856
ko05410	Hypertrophic cardiomyopathy (HCM)	21/806	100/7206	0.00363711951177
ko04141	Protein processing in endoplasmic reticulum	9/806	184/7206	0.00415868814618
ko04015	Rap1 signaling pathway	46/806	278/7206	0.00628613632843
ko04745	Phototransduction - fly	10/806	38/7206	0.00737973650952
ko04260	Cardiac muscle contraction	20/806	98/7206	0.00863505808207
ko04971	Gastric acid secretion	20/806	98/7206	0.00863505808207
ko00240	Pyrimidine metabolism	4/806	110/7206	0.00865402408362
ko04621	NOD-like receptor signaling pathway	8/806	157/7206	0.0103164458479
ko04610	Complement and coagulation cascades	2/806	79/7206	0.0105382640985
ko00562	Inositol phosphate metabolism	18/806	89/7206	0.0105456129252
ko04217	Necroptosis	10/806	178/7206	0.0153799862812
ko05133	Pertussis	3/806	87/7206	0.0158646383034
ko04923	Regulation of lipolysis in adipocytes	16/806	77/7206	0.0159804132732
ko04740	Olfactory transduction	16/806	80/7206	0.0188356004866
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/806	59/7206	0.0194196301264
ko04120	Ubiquitin mediated proteolysis	7/806	138/7206	0.0195396984342
ko04960	Aldosterone-regulated sodium reabsorption	10/806	41/7206	0.0204803708749
ko04214	Apoptosis - fly	2/806	72/7206	0.0217527680043
ko04973	Carbohydrate digestion and absorption	10/806	42/7206	0.0220026776692
ko04922	Glucagon signaling pathway	23/806	128/7206	0.0222252594012
ko04540	Gap junction	23/806	128/7206	0.0222252594012
ko05010	Alzheimer's disease	33/806	202/7206	0.0231482711615
ko05205	Proteoglycans in cancer	19/806	271/7206	0.0237327050129
ko05169	Epstein-Barr virus infection	13/806	206/7206	0.0241794303746
ko04071	Sphingolipid signaling pathway	27/806	162/7206	0.0314219676018
ko04964	Proximal tubule bicarbonate reclamation	7/806	29/7206	0.0369205692601
ko05219	Bladder cancer	1/806	48/7206	0.038316436578
ko05140	Leishmaniasis	3/806	75/7206	0.0428151894057
ko00680	Methane metabolism	8/806	34/7206	0.048149747302
ko04711	Circadian rhythm - fly	4/806	13/7206	0.04871303955