ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 37/543 191/7206 6.26968828906e-08 ko00350 Tyrosine metabolism 12/543 33/7206 2.42518384759e-06 ko00120 Primary bile acid biosynthesis 9/543 20/7206 5.79803944228e-06 ko04380 Osteoclast differentiation 25/543 134/7206 1.77604138655e-05 ko00140 Steroid hormone biosynthesis 12/543 41/7206 3.08579499356e-05 ko00643 Styrene degradation 4/543 4/7206 3.19135251815e-05 ko03013 RNA transport 1/543 166/7206 6.80363575616e-05 ko04974 Protein digestion and absorption 19/543 96/7206 7.84934618271e-05 ko04064 NF-kappa B signaling pathway 18/543 96/7206 0.000246704132535 ko04621 NOD-like receptor signaling pathway 25/543 157/7206 0.000315661278197 ko04110 Cell cycle 1/543 145/7206 0.00032353582406 ko00950 Isoquinoline alkaloid biosynthesis 5/543 10/7206 0.000436962327804 ko00983 Drug metabolism - other enzymes 10/543 42/7206 0.000881042591019 ko00051 Fructose and mannose metabolism 10/543 42/7206 0.000881042591019 ko03010 Ribosome 1/543 129/7206 0.00102346453485 ko00360 Phenylalanine metabolism 6/543 17/7206 0.00107324000118 ko04933 AGE-RAGE signaling pathway in diabetic complications 21/543 135/7206 0.00136308961704 ko05146 Amoebiasis 17/543 99/7206 0.00144656749817 ko05034 Alcoholism 6/543 238/7206 0.00156310880698 ko00960 Tropane, piperidine and pyridine alkaloid biosynthesis 3/543 4/7206 0.00160702329024 ko03040 Spliceosome 2/543 145/7206 0.00204820255722 ko04610 Complement and coagulation cascades 14/543 79/7206 0.0020741342363 ko04512 ECM-receptor interaction 14/543 79/7206 0.0020741342363 ko05164 Influenza A 24/543 167/7206 0.0025192741423 ko04120 Ubiquitin mediated proteolysis 2/543 138/7206 0.00284822612194 ko00380 Tryptophan metabolism 10/543 50/7206 0.00356520155532 ko00400 Phenylalanine, tyrosine and tryptophan biosynthesis 3/543 5/7206 0.00379253729781 ko03320 PPAR signaling pathway 12/543 69/7206 0.0049494418383 ko00982 Drug metabolism - cytochrome P450 8/543 37/7206 0.0054026773603 ko04650 Natural killer cell mediated cytotoxicity 15/543 97/7206 0.00614354451812 ko05321 Inflammatory bowel disease (IBD) 10/543 56/7206 0.00822918740891 ko05145 Toxoplasmosis 18/543 126/7206 0.00917905726079 ko03015 mRNA surveillance pathway 1/543 93/7206 0.00944712214667 ko04960 Aldosterone-regulated sodium reabsorption 8/543 41/7206 0.0102545056159 ko00592 alpha-Linolenic acid metabolism 5/543 19/7206 0.0114213363864 ko05162 Measles 17/543 120/7206 0.0127784559863 ko05160 Hepatitis C 20/543 153/7206 0.0129345415522 ko04723 Retrograde endocannabinoid signaling 5/543 175/7206 0.0131245892841 ko04710 Circadian rhythm 8/543 43/7206 0.0136357318092 ko04391 Hippo signaling pathway - fly 1/543 90/7206 0.0140023595993 ko04611 Platelet activation 21/543 163/7206 0.0150868265301 ko05150 Staphylococcus aureus infection 7/543 36/7206 0.0162549227924 ko04390 Hippo signaling pathway 6/543 188/7206 0.0170440823632 ko04930 Type II diabetes mellitus 9/543 54/7206 0.0183944017775 ko04672 Intestinal immune network for IgA production 7/543 37/7206 0.0187871133933 ko04668 TNF signaling pathway 16/543 120/7206 0.0221543280985 ko05340 Primary immunodeficiency 6/543 30/7206 0.0223040461441 ko00330 Arginine and proline metabolism 10/543 61/7206 0.0231072415041 ko04666 Fc gamma R-mediated phagocytosis 16/543 122/7206 0.0243210120055 ko05204 Chemical carcinogenesis 8/543 48/7206 0.0255364657385 ko04630 Jak-STAT signaling pathway 17/543 132/7206 0.0284745649561 ko00220 Arginine biosynthesis 5/543 24/7206 0.0305934896328 ko04510 Focal adhesion 27/543 240/7206 0.033635036855 ko00052 Galactose metabolism 6/543 33/7206 0.0343951892477 ko00830 Retinol metabolism 7/543 42/7206 0.0356347793273 ko04657 IL-17 signaling pathway 12/543 87/7206 0.0377426147629 ko04659 Th17 cell differentiation 14/543 106/7206 0.0383776161294 ko04662 B cell receptor signaling pathway 12/543 88/7206 0.0395596732841 ko05224 Breast cancer 6/543 174/7206 0.0402578248597 ko04922 Glucagon signaling pathway 16/543 128/7206 0.040945216371 ko04020 Calcium signaling pathway 29/543 265/7206 0.0426013110405 ko05322 Systemic lupus erythematosus 5/543 151/7206 0.0427318426368 ko00500 Starch and sucrose metabolism 6/543 35/7206 0.0444296692351 ko04622 RIG-I-like receptor signaling pathway 9/543 62/7206 0.0489152222866 ko04022 cGMP-PKG signaling pathway 24/543 216/7206 0.0491674506007