ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 31/187 191/7206 8.09849695481e-17 ko05340 Primary immunodeficiency 13/187 30/7206 1.29975204947e-13 ko04650 Natural killer cell mediated cytotoxicity 20/187 97/7206 3.32156283808e-13 ko04612 Antigen processing and presentation 16/187 77/7206 7.62188522848e-11 ko05330 Allograft rejection 10/187 24/7206 1.55939263082e-10 ko05164 Influenza A 22/187 167/7206 2.39790290073e-10 ko05320 Autoimmune thyroid disease 10/187 29/7206 1.42249235754e-09 ko05145 Toxoplasmosis 18/187 126/7206 3.04417706139e-09 ko05332 Graft-versus-host disease 8/187 18/7206 6.20873282744e-09 ko05168 Herpes simplex infection 21/187 182/7206 7.34151630972e-09 ko05162 Measles 17/187 120/7206 9.73872215119e-09 ko04659 Th17 cell differentiation 16/187 106/7206 1.06402746241e-08 ko05152 Tuberculosis 21/187 187/7206 1.19783550812e-08 ko05321 Inflammatory bowel disease (IBD) 12/187 56/7206 1.34995517466e-08 ko04658 Th1 and Th2 cell differentiation 14/187 96/7206 1.43418367438e-07 ko04630 Jak-STAT signaling pathway 16/187 132/7206 2.51688436788e-07 ko05140 Leishmaniasis 12/187 75/7206 4.10425007053e-07 ko04940 Type I diabetes mellitus 8/187 32/7206 1.0923538228e-06 ko04660 T cell receptor signaling pathway 14/187 124/7206 3.44974887462e-06 ko04064 NF-kappa B signaling pathway 12/187 96/7206 6.09703950465e-06 ko04217 Necroptosis 16/187 178/7206 1.35998402869e-05 ko04062 Chemokine signaling pathway 17/187 201/7206 1.62621775837e-05 ko04640 Hematopoietic cell lineage 9/187 64/7206 3.53707873141e-05 ko04672 Intestinal immune network for IgA production 7/187 37/7206 3.77078402406e-05 ko05310 Asthma 5/187 17/7206 5.35614138011e-05 ko03050 Proteasome 8/187 54/7206 6.62845013312e-05 ko04145 Phagosome 14/187 162/7206 7.38019188426e-05 ko05323 Rheumatoid arthritis 10/187 89/7206 9.34991989003e-05 ko05144 Malaria 7/187 45/7206 0.000139464597683 ko04380 Osteoclast differentiation 12/187 134/7206 0.000174037564644 ko04621 NOD-like receptor signaling pathway 13/187 157/7206 0.000206098975892 ko04620 Toll-like receptor signaling pathway 10/187 100/7206 0.000248698039517 ko05150 Staphylococcus aureus infection 6/187 36/7206 0.000286964995914 ko05133 Pertussis 9/187 87/7206 0.000394381062584 ko05416 Viral myocarditis 7/187 55/7206 0.000501158986514 ko04514 Cell adhesion molecules (CAMs) 11/187 130/7206 0.000529712841612 ko05161 Hepatitis B 12/187 173/7206 0.0017405154625 ko04662 B cell receptor signaling pathway 8/187 88/7206 0.00193340575854 ko04611 Platelet activation 11/187 163/7206 0.00332891245819 ko04664 Fc epsilon RI signaling pathway 7/187 77/7206 0.00368029266419 ko05132 Salmonella infection 8/187 98/7206 0.00380080881141 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/187 191/7206 0.00395388559475 ko05142 Chagas disease (American trypanosomiasis) 9/187 130/7206 0.00652867160579 ko00590 Arachidonic acid metabolism 5/187 52/7206 0.0108070382179 ko05034 Alcoholism 1/187 238/7206 0.0218404165284 ko04622 RIG-I-like receptor signaling pathway 5/187 62/7206 0.0218880450082 ko04360 Axon guidance 1/187 233/7206 0.0325187577617 ko04666 Fc gamma R-mediated phagocytosis 7/187 122/7206 0.0390078449047 ko05143 African trypanosomiasis 3/187 32/7206 0.0491778516795