ko pathway ratio_in_study ratio_in_pop p_value ko05164 Influenza A 19/225 167/7206 9.31637807243e-07 ko04610 Complement and coagulation cascades 11/225 79/7206 2.99875552304e-05 ko05152 Tuberculosis 17/225 187/7206 6.91479839832e-05 ko05162 Measles 13/225 120/7206 8.61173561207e-05 ko04060 Cytokine-cytokine receptor interaction 17/225 191/7206 9.01171771807e-05 ko05150 Staphylococcus aureus infection 7/225 36/7206 0.000101552077715 ko04666 Fc gamma R-mediated phagocytosis 13/225 122/7206 0.000102190918408 ko04672 Intestinal immune network for IgA production 7/225 37/7206 0.00012196186149 ko05145 Toxoplasmosis 13/225 126/7206 0.000142257238472 ko05340 Primary immunodeficiency 6/225 30/7206 0.000274403877674 ko05321 Inflammatory bowel disease (IBD) 8/225 56/7206 0.000310790569584 ko04621 NOD-like receptor signaling pathway 14/225 157/7206 0.000371756549453 ko05140 Leishmaniasis 9/225 75/7206 0.000502413759836 ko04070 Phosphatidylinositol signaling system 11/225 112/7206 0.000705296032932 ko04658 Th1 and Th2 cell differentiation 10/225 96/7206 0.000775190265261 ko04650 Natural killer cell mediated cytotoxicity 10/225 97/7206 0.000841133250944 ko04933 AGE-RAGE signaling pathway in diabetic complications 12/225 135/7206 0.00099858106303 ko04659 Th17 cell differentiation 10/225 106/7206 0.00166886096257 ko00051 Fructose and mannose metabolism 6/225 42/7206 0.00177375621726 ko04514 Cell adhesion molecules (CAMs) 11/225 130/7206 0.00239086824037 ko04612 Antigen processing and presentation 8/225 77/7206 0.00262650296444 ko05166 HTLV-I infection 19/225 292/7206 0.00271845181632 ko04380 Osteoclast differentiation 11/225 134/7206 0.00303291265949 ko05230 Central carbon metabolism in cancer 8/225 81/7206 0.00360946606769 ko04217 Necroptosis 13/225 178/7206 0.00367997253961 ko04620 Toll-like receptor signaling pathway 9/225 100/7206 0.00388203821776 ko05168 Herpes simplex infection 13/225 182/7206 0.00444733127979 ko04919 Thyroid hormone signaling pathway 11/225 143/7206 0.0049891306426 ko05330 Allograft rejection 4/225 24/7206 0.00601410924994 ko05416 Viral myocarditis 6/225 55/7206 0.00700462355002 ko00140 Steroid hormone biosynthesis 5/225 41/7206 0.00851085821376 ko04960 Aldosterone-regulated sodium reabsorption 5/225 41/7206 0.00851085821376 ko05231 Choline metabolism in cancer 10/225 134/7206 0.00896894880167 ko04664 Fc epsilon RI signaling pathway 7/225 77/7206 0.0099284239958 ko04064 NF-kappa B signaling pathway 8/225 96/7206 0.00999852049493 ko04512 ECM-receptor interaction 7/225 79/7206 0.0113592458352 ko05161 Hepatitis B 12/225 173/7206 0.0116323961639 ko05320 Autoimmune thyroid disease 4/225 29/7206 0.0119045773686 ko05146 Amoebiasis 8/225 99/7206 0.0119257797015 ko05205 Proteoglycans in cancer 16/225 271/7206 0.0120871742179 ko04622 RIG-I-like receptor signaling pathway 6/225 62/7206 0.0124090170132 ko04750 Inflammatory mediator regulation of TRP channels 9/225 122/7206 0.0138264729867 ko04640 Hematopoietic cell lineage 6/225 64/7206 0.0143782595467 ko04066 HIF-1 signaling pathway 9/225 123/7206 0.0145262278006 ko05310 Asthma 3/225 17/7206 0.0147759035975 ko04660 T cell receptor signaling pathway 9/225 124/7206 0.0152518373194 ko05332 Graft-versus-host disease 3/225 18/7206 0.0173299813279 ko04611 Platelet activation 11/225 163/7206 0.0182231516041 ko05167 Kaposi's sarcoma-associated herpesvirus infection 12/225 191/7206 0.0183690797905 ko04662 B cell receptor signaling pathway 7/225 88/7206 0.0196842682137 ko04068 FoxO signaling pathway 11/225 167/7206 0.0199132102965 ko05323 Rheumatoid arthritis 7/225 89/7206 0.0208175064473 ko00120 Primary bile acid biosynthesis 3/225 20/7206 0.0231306377782 ko00966 Glucosinolate biosynthesis 1/225 1/7206 0.0312239800167 ko04668 TNF signaling pathway 8/225 120/7206 0.0337162657539 ko04015 Rap1 signaling pathway 15/225 278/7206 0.0337616640152 ko04152 AMPK signaling pathway 10/225 161/7206 0.0346425508198 ko00564 Glycerophospholipid metabolism 7/225 99/7206 0.0347286798713 ko05214 Glioma 6/225 79/7206 0.0363821016244 ko00565 Ether lipid metabolism 4/225 42/7206 0.0410385595586 ko04137 Mitophagy - animal 6/225 82/7206 0.0424821406298