ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 22/220 191/7206 6.58888749632e-08 ko00140 Steroid hormone biosynthesis 7/220 41/7206 0.000208500431694 ko04070 Phosphatidylinositol signaling system 11/220 112/7206 0.000584413721554 ko04020 Calcium signaling pathway 19/220 265/7206 0.000677041783836 ko05231 Choline metabolism in cancer 12/220 134/7206 0.000767430103291 ko00564 Glycerophospholipid metabolism 10/220 99/7206 0.000830306217054 ko04610 Complement and coagulation cascades 8/220 79/7206 0.00268761746244 ko04072 Phospholipase D signaling pathway 14/220 197/7206 0.00273105329004 ko04022 cGMP-PKG signaling pathway 15/220 216/7206 0.00354774967242 ko05031 Amphetamine addiction 8/220 91/7206 0.00641256769812 ko04064 NF-kappa B signaling pathway 8/220 96/7206 0.00879151969232 ko04650 Natural killer cell mediated cytotoxicity 8/220 97/7206 0.00933741451191 ko04725 Cholinergic synapse 11/220 160/7206 0.0096487873376 ko04971 Gastric acid secretion 8/220 98/7206 0.00990822232574 ko05230 Central carbon metabolism in cancer 7/220 81/7206 0.0115305305533 ko04912 GnRH signaling pathway 9/220 122/7206 0.0120697525281 ko04750 Inflammatory mediator regulation of TRP channels 9/220 122/7206 0.0120697525281 ko04925 Aldosterone synthesis and secretion 8/220 105/7206 0.0146566682116 ko00590 Arachidonic acid metabolism 5/220 52/7206 0.020557586592 ko00120 Primary bile acid biosynthesis 3/220 20/7206 0.0218076118627 ko00100 Steroid biosynthesis 3/220 21/7206 0.0248820157666 ko04672 Intestinal immune network for IgA production 4/220 37/7206 0.0253880055782 ko00982 Drug metabolism - cytochrome P450 4/220 37/7206 0.0253880055782 ko04745 Phototransduction - fly 4/220 38/7206 0.0277166607866 ko00966 Glucosinolate biosynthesis 1/220 1/7206 0.030530113794 ko05152 Tuberculosis 11/220 187/7206 0.0305456555751 ko05214 Glioma 6/220 79/7206 0.0331254499722 ko04960 Aldosterone-regulated sodium reabsorption 4/220 41/7206 0.0354463638678 ko00051 Fructose and mannose metabolism 4/220 42/7206 0.0382730471094 ko01040 Biosynthesis of unsaturated fatty acids 3/220 25/7206 0.0393770941367 ko04710 Circadian rhythm 4/220 43/7206 0.0412253849986 ko04924 Renin secretion 6/220 86/7206 0.0471278175454 ko04918 Thyroid hormone synthesis 6/220 86/7206 0.0471278175454