ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	200/1317	423/7206	2.03739216841e-45
ko04724	Glutamatergic synapse	88/1317	152/7206	3.23466056007e-28
ko05033	Nicotine addiction	47/1317	56/7206	1.40271994584e-26
ko04713	Circadian entrainment	77/1317	136/7206	5.96066212286e-24
ko05032	Morphine addiction	67/1317	110/7206	1.79008598825e-23
ko04727	GABAergic synapse	65/1317	110/7206	8.83132763163e-22
ko04020	Calcium signaling pathway	111/1317	265/7206	7.48454847398e-20
ko04728	Dopaminergic synapse	86/1317	185/7206	4.65436437642e-19
ko04725	Cholinergic synapse	76/1317	160/7206	1.22631711225e-17
ko04721	Synaptic vesicle cycle	49/1317	80/7206	1.25096710598e-17
ko04723	Retrograde endocannabinoid signaling	78/1317	175/7206	7.1912636824e-16
ko04024	cAMP signaling pathway	106/1317	279/7206	2.85749131613e-15
ko04726	Serotonergic synapse	63/1317	137/7206	5.36895139664e-14
ko04911	Insulin secretion	55/1317	117/7206	7.2285941725e-13
ko04742	Taste transduction	36/1317	61/7206	1.3440622216e-12
ko04921	Oxytocin signaling pathway	81/1317	209/7206	1.97497140253e-12
ko05031	Amphetamine addiction	44/1317	91/7206	4.57388859605e-11
ko03010	Ribosome	1/1317	129/7206	2.02989653371e-10
ko04744	Phototransduction	24/1317	36/7206	2.09133612021e-10
ko04970	Salivary secretion	44/1317	95/7206	2.71472186432e-10
ko03040	Spliceosome	3/1317	145/7206	1.47406827496e-09
ko04720	Long-term potentiation	42/1317	99/7206	1.96821561855e-08
ko05322	Systemic lupus erythematosus	5/1317	151/7206	2.82097421701e-08
ko04022	cGMP-PKG signaling pathway	72/1317	216/7206	8.0697791437e-08
ko04261	Adrenergic signaling in cardiomyocytes	69/1317	205/7206	1.03014977976e-07
ko04925	Aldosterone synthesis and secretion	42/1317	105/7206	1.48000008803e-07
ko05030	Cocaine addiction	32/1317	73/7206	3.64149623511e-07
ko03013	RNA transport	8/1317	166/7206	3.91936708625e-07
ko05203	Viral carcinogenesis	22/1317	277/7206	1.04167954234e-06
ko04971	Gastric acid secretion	38/1317	98/7206	1.9306016338e-06
ko04110	Cell cycle	8/1317	145/7206	1.02436004006e-05
ko04070	Phosphatidylinositol signaling system	40/1317	112/7206	1.03141785013e-05
ko04141	Protein processing in endoplasmic reticulum	13/1317	184/7206	1.69776882695e-05
ko03008	Ribosome biogenesis in eukaryotes	2/1317	79/7206	2.84901120968e-05
ko04924	Renin secretion	32/1317	86/7206	2.97409750877e-05
ko04966	Collecting duct acid secretion	14/1317	26/7206	4.63788114637e-05
ko04710	Circadian rhythm	19/1317	43/7206	7.63212814942e-05
ko04730	Long-term depression	29/1317	78/7206	8.18434838348e-05
ko04745	Phototransduction - fly	17/1317	38/7206	0.000150542220362
ko05164	Influenza A	13/1317	167/7206	0.000155003980821
ko05169	Epstein-Barr virus infection	18/1317	206/7206	0.000155932474059
ko04014	Ras signaling pathway	76/1317	279/7206	0.000186232905349
ko05168	Herpes simplex infection	15/1317	182/7206	0.000193254869383
ko05014	Amyotrophic lateral sclerosis (ALS)	27/1317	74/7206	0.000198826117098
ko04072	Phospholipase D signaling pathway	57/1317	197/7206	0.000234951464225
ko04371	Apelin signaling pathway	52/1317	177/7206	0.000245152688441
ko00520	Amino sugar and nucleotide sugar metabolism	1/1317	55/7206	0.000324411378773
ko04740	Olfactory transduction	28/1317	80/7206	0.000361138454979
ko04010	MAPK signaling pathway	84/1317	321/7206	0.000365606028004
ko04270	Vascular smooth muscle contraction	46/1317	154/7206	0.000440119992669
ko05161	Hepatitis B	15/1317	173/7206	0.000457064258513
ko04972	Pancreatic secretion	35/1317	111/7206	0.000708238957949
ko04922	Glucagon signaling pathway	39/1317	128/7206	0.000723594141796
ko04540	Gap junction	39/1317	128/7206	0.000723594141796
ko04360	Axon guidance	63/1317	233/7206	0.000743659338606
ko04120	Ubiquitin mediated proteolysis	11/1317	138/7206	0.0007845566039
ko04514	Cell adhesion molecules (CAMs)	39/1317	130/7206	0.00118675775057
ko04750	Inflammatory mediator regulation of TRP channels	37/1317	122/7206	0.00125013522872
ko05205	Proteoglycans in cancer	30/1317	271/7206	0.00129029846221
ko05110	Vibrio cholerae infection	22/1317	63/7206	0.00152288289319
ko03420	Nucleotide excision repair	1/1317	46/7206	0.00174341485971
ko04976	Bile secretion	26/1317	80/7206	0.00198070716829
ko04923	Regulation of lipolysis in adipocytes	25/1317	77/7206	0.00262233456206
ko03022	Basal transcription factors	1/1317	44/7206	0.00266403358456
ko05162	Measles	10/1317	120/7206	0.00278151784798
ko05133	Pertussis	6/1317	87/7206	0.00325438422175
ko04621	NOD-like receptor signaling pathway	15/1317	157/7206	0.00326117799
ko05166	HTLV-I infection	35/1317	292/7206	0.00410215784651
ko04711	Circadian rhythm - fly	7/1317	13/7206	0.00411044928148
ko04622	RIG-I-like receptor signaling pathway	3/1317	62/7206	0.00426318749409
ko04612	Antigen processing and presentation	5/1317	77/7206	0.00452170286836
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	25/1317	79/7206	0.00477752313829
ko05414	Dilated cardiomyopathy	32/1317	112/7206	0.00651753817517
ko04930	Type II diabetes mellitus	18/1317	54/7206	0.00723293169991
ko04060	Cytokine-cytokine receptor interaction	21/1317	191/7206	0.00760996803051
ko04915	Estrogen signaling pathway	36/1317	131/7206	0.00841242783962
ko04214	Apoptosis - fly	5/1317	72/7206	0.00885052739552
ko04630	Jak-STAT signaling pathway	13/1317	132/7206	0.00885318038755
ko05131	Shigellosis	6/1317	82/7206	0.00887436003613
ko04626	Plant-pathogen interaction	8/1317	18/7206	0.00938144392085
ko00630	Glyoxylate and dicarboxylate metabolism	1/1317	38/7206	0.00960829369138
ko03410	Base excision repair	1/1317	38/7206	0.00960829369138
ko04064	NF-kappa B signaling pathway	8/1317	96/7206	0.0107724316957
ko05144	Malaria	2/1317	45/7206	0.0111668950609
ko04610	Complement and coagulation cascades	6/1317	79/7206	0.0119874385509
ko00280	Valine, leucine and isoleucine degradation	3/1317	54/7206	0.0122572815558
ko04964	Proximal tubule bicarbonate reclamation	11/1317	29/7206	0.0128820867204
ko04217	Necroptosis	20/1317	178/7206	0.0136802616875
ko00860	Porphyrin and chlorophyll metabolism	1/1317	34/7206	0.0137908080102
ko05016	Huntington's disease	26/1317	215/7206	0.0154735420717
ko05140	Leishmaniasis	6/1317	75/7206	0.0162703789758
ko05130	Pathogenic Escherichia coli infection	6/1317	77/7206	0.016569403121
ko04210	Apoptosis	21/1317	180/7206	0.0188412641515
ko05145	Toxoplasmosis	13/1317	126/7206	0.0194235871479
ko00965	Betalain biosynthesis	3/1317	4/7206	0.0210391330693
ko05231	Choline metabolism in cancer	35/1317	134/7206	0.0234145000149
ko04260	Cardiac muscle contraction	27/1317	98/7206	0.0242447039339
ko04657	IL-17 signaling pathway	8/1317	87/7206	0.0251723540618
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/1317	14/7206	0.0291262804442
ko05340	Primary immunodeficiency	1/1317	30/7206	0.0312246678841
ko04932	Non-alcoholic fatty liver disease (NAFLD)	22/1317	182/7206	0.0319745889785
ko03018	RNA degradation	8/1317	84/7206	0.0334406483458
ko05416	Viral myocarditis	4/1317	55/7206	0.0342642066356
ko05219	Bladder cancer	3/1317	48/7206	0.0366081030833
ko01524	Platinum drug resistance	7/1317	76/7206	0.0369208261164
ko04960	Aldosterone-regulated sodium reabsorption	13/1317	41/7206	0.0395721127204
ko05200	Pathways in cancer	73/1317	492/7206	0.0400090027812
ko05217	Basal cell carcinoma	6/1317	68/7206	0.0405112580165
ko04113	Meiosis - yeast	6/1317	70/7206	0.041518970267
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/1317	59/7206	0.0420818547986
ko04973	Carbohydrate digestion and absorption	13/1317	42/7206	0.0433856649438
ko00240	Pyrimidine metabolism	12/1317	110/7206	0.0460810267438
ko05215	Prostate cancer	12/1317	111/7206	0.0465589255955
ko05206	MicroRNAs in cancer	22/1317	177/7206	0.0481844670285
ko04115	p53 signaling pathway	7/1317	74/7206	0.0490595330981