ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	169/965	423/7206	1.96472380744e-45
ko04724	Glutamatergic synapse	78/965	152/7206	9.94871677261e-30
ko05033	Nicotine addiction	43/965	56/7206	4.10206745507e-27
ko04713	Circadian entrainment	65/965	136/7206	1.06526706793e-22
ko05032	Morphine addiction	57/965	110/7206	3.01178676525e-22
ko04728	Dopaminergic synapse	75/965	185/7206	1.25343221046e-20
ko04721	Synaptic vesicle cycle	45/965	80/7206	1.08019637568e-19
ko04727	GABAergic synapse	53/965	110/7206	6.5810227384e-19
ko04725	Cholinergic synapse	64/965	160/7206	2.12498666099e-17
ko04723	Retrograde endocannabinoid signaling	67/965	175/7206	5.45877294144e-17
ko04020	Calcium signaling pathway	87/965	265/7206	9.72867081343e-17
ko04921	Oxytocin signaling pathway	73/965	209/7206	7.17796531924e-16
ko04024	cAMP signaling pathway	86/965	279/7206	1.0639063207e-14
ko04911	Insulin secretion	49/965	117/7206	1.58416942061e-14
ko04726	Serotonergic synapse	52/965	137/7206	2.85778847404e-13
ko05031	Amphetamine addiction	38/965	91/7206	1.6619062168e-11
ko04970	Salivary secretion	39/965	95/7206	1.69104804888e-11
ko04261	Adrenergic signaling in cardiomyocytes	63/965	205/7206	5.04382420778e-11
ko04742	Taste transduction	29/965	61/7206	9.67161224677e-11
ko04720	Long-term potentiation	37/965	99/7206	1.35897181658e-09
ko04925	Aldosterone synthesis and secretion	36/965	105/7206	3.22098313835e-08
ko03040	Spliceosome	1/965	145/7206	3.79419960357e-08
ko04120	Ubiquitin mediated proteolysis	1/965	138/7206	8.31028924204e-08
ko04730	Long-term depression	29/965	78/7206	9.50175536411e-08
ko05014	Amyotrophic lateral sclerosis (ALS)	27/965	74/7206	4.1012549518e-07
ko05203	Viral carcinogenesis	12/965	277/7206	5.3424094992e-07
ko04971	Gastric acid secretion	32/965	98/7206	6.62253901628e-07
ko05168	Herpes simplex infection	5/965	182/7206	1.26795559197e-06
ko05322	Systemic lupus erythematosus	3/965	151/7206	1.38324296502e-06
ko05030	Cocaine addiction	25/965	73/7206	4.19536316876e-06
ko04744	Phototransduction	16/965	36/7206	4.99688575634e-06
ko05164	Influenza A	5/965	167/7206	5.36847521129e-06
ko04514	Cell adhesion molecules (CAMs)	37/965	130/7206	5.40437472889e-06
ko04022	cGMP-PKG signaling pathway	53/965	216/7206	6.37698448687e-06
ko04010	MAPK signaling pathway	72/965	321/7206	7.12228379975e-06
ko04966	Collecting duct acid secretion	13/965	26/7206	7.90700387322e-06
ko04360	Axon guidance	56/965	233/7206	8.11207328355e-06
ko04745	Phototransduction - fly	16/965	38/7206	1.16934304982e-05
ko04972	Pancreatic secretion	32/965	111/7206	1.50550133828e-05
ko04540	Gap junction	35/965	128/7206	3.2040717033e-05
ko04740	Olfactory transduction	25/965	80/7206	3.52566236849e-05
ko05110	Vibrio cholerae infection	21/965	63/7206	3.88824053465e-05
ko03013	RNA transport	6/965	166/7206	4.00843736975e-05
ko04070	Phosphatidylinositol signaling system	31/965	112/7206	5.83333702403e-05
ko05162	Measles	3/965	120/7206	6.40092606668e-05
ko04260	Cardiac muscle contraction	28/965	98/7206	6.51443036693e-05
ko04621	NOD-like receptor signaling pathway	6/965	157/7206	7.65921581606e-05
ko04060	Cytokine-cytokine receptor interaction	9/965	191/7206	9.22868358296e-05
ko04014	Ras signaling pathway	60/965	279/7206	0.000146316145775
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	23/965	79/7206	0.000191138961128
ko05169	Epstein-Barr virus infection	11/965	206/7206	0.000240911708141
ko05166	HTLV-I infection	20/965	292/7206	0.00041752709837
ko04141	Protein processing in endoplasmic reticulum	10/965	184/7206	0.000606236771623
ko04750	Inflammatory mediator regulation of TRP channels	30/965	122/7206	0.000692303595084
ko04924	Renin secretion	23/965	86/7206	0.00110371020227
ko04110	Cell cycle	7/965	145/7206	0.00118754062997
ko04626	Plant-pathogen interaction	8/965	18/7206	0.00126734880612
ko04961	Endocrine and other factor-regulated calcium reabsorption	17/965	59/7206	0.00158531427635
ko04072	Phospholipase D signaling pathway	42/965	197/7206	0.00192444657555
ko04960	Aldosterone-regulated sodium reabsorption	13/965	41/7206	0.00193193387806
ko04612	Antigen processing and presentation	2/965	77/7206	0.00212228858811
ko03008	Ribosome biogenesis in eukaryotes	2/965	79/7206	0.00223862363459
ko04146	Peroxisome	3/965	89/7206	0.00255194649662
ko04964	Proximal tubule bicarbonate reclamation	10/965	29/7206	0.00318611276941
ko00330	Arginine and proline metabolism	1/965	61/7206	0.00363738835104
ko04064	NF-kappa B signaling pathway	4/965	96/7206	0.00396574493585
ko04630	Jak-STAT signaling pathway	7/965	132/7206	0.00413911724585
ko05414	Dilated cardiomyopathy	26/965	112/7206	0.00459086172698
ko04371	Apelin signaling pathway	37/965	177/7206	0.00493340801865
ko04915	Estrogen signaling pathway	29/965	131/7206	0.00598744823052
ko00604	Glycosphingolipid biosynthesis - ganglio series	6/965	14/7206	0.0065423616516
ko04610	Complement and coagulation cascades	3/965	79/7206	0.00734958815021
ko05410	Hypertrophic cardiomyopathy (HCM)	23/965	100/7206	0.0073711501505
ko00562	Inositol phosphate metabolism	21/965	89/7206	0.00737417095017
ko05161	Hepatitis B	12/965	173/7206	0.00909708145509
ko01524	Platinum drug resistance	3/965	76/7206	0.0104169267483
ko04710	Circadian rhythm	12/965	43/7206	0.0109442081277
ko05222	Small cell lung cancer	4/965	89/7206	0.011109503459
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/965	92/7206	0.0126353295483
ko04330	Notch signaling pathway	2/965	62/7206	0.0136411547098
ko04217	Necroptosis	13/965	178/7206	0.0138104647355
ko05205	Proteoglycans in cancer	23/965	271/7206	0.0139021549419
ko05016	Huntington's disease	17/965	215/7206	0.0144325421339
ko04214	Apoptosis - fly	3/965	72/7206	0.0147214364828
ko00310	Lysine degradation	3/965	73/7206	0.01472180444
ko05140	Leishmaniasis	3/965	75/7206	0.0153593953401
ko03420	Nucleotide excision repair	1/965	46/7206	0.0166055025439
ko05145	Toxoplasmosis	8/965	126/7206	0.0168839046427
ko04922	Glucagon signaling pathway	27/965	128/7206	0.0174012636325
ko04015	Rap1 signaling pathway	51/965	278/7206	0.0190770749919
ko04932	Non-alcoholic fatty liver disease (NAFLD)	14/965	182/7206	0.0202472584642
ko04918	Thyroid hormone synthesis	19/965	86/7206	0.0244627977306
ko00071	Fatty acid degradation	1/965	45/7206	0.0251387027651
ko04912	GnRH signaling pathway	25/965	122/7206	0.0305704142808
ko04510	Focal adhesion	21/965	240/7206	0.0333786946228
ko04916	Melanogenesis	28/965	142/7206	0.0333868324978
ko00980	Metabolism of xenobiotics by cytochrome P450	1/965	40/7206	0.0360924148891
ko00140	Steroid hormone biosynthesis	1/965	41/7206	0.0362576422649
ko04550	Signaling pathways regulating pluripotency of stem cells	13/965	165/7206	0.0366402484543
ko05220	Chronic myeloid leukemia	5/965	85/7206	0.0372074475901
ko00680	Methane metabolism	9/965	34/7206	0.0384273540756
ko04115	p53 signaling pathway	4/965	74/7206	0.0392767170689
ko05200	Pathways in cancer	51/965	492/7206	0.0397650580158
ko00590	Arachidonic acid metabolism	2/965	52/7206	0.0398967612332
ko04640	Hematopoietic cell lineage	3/965	64/7206	0.040729284731
ko00280	Valine, leucine and isoleucine degradation	2/965	54/7206	0.0414756651666
ko04976	Bile secretion	17/965	80/7206	0.0464533016398
ko04611	Platelet activation	13/965	163/7206	0.0468286583678