ko	pathway	ratio_in_study	ratio_in_pop	p_value
ko04080	Neuroactive ligand-receptor interaction	127/897	423/7206	2.8303226169e-23
ko04724	Glutamatergic synapse	61/897	152/7206	2.69053198339e-18
ko04713	Circadian entrainment	54/897	136/7206	4.37861745509e-16
ko04727	GABAergic synapse	47/897	110/7206	1.26969382693e-15
ko05032	Morphine addiction	46/897	110/7206	6.90081561367e-15
ko05033	Nicotine addiction	31/897	56/7206	1.39500153648e-14
ko04721	Synaptic vesicle cycle	37/897	80/7206	7.00558566555e-14
ko04723	Retrograde endocannabinoid signaling	56/897	175/7206	5.35031623636e-12
ko04921	Oxytocin signaling pathway	62/897	209/7206	1.5703043406e-11
ko04024	cAMP signaling pathway	74/897	279/7206	1.01071510241e-10
ko04020	Calcium signaling pathway	71/897	265/7206	1.20189804714e-10
ko04970	Salivary secretion	36/897	95/7206	1.8537289655e-10
ko04728	Dopaminergic synapse	55/897	185/7206	2.18068656168e-10
ko04911	Insulin secretion	40/897	117/7206	6.87287380767e-10
ko04725	Cholinergic synapse	48/897	160/7206	2.58175671716e-09
ko04022	cGMP-PKG signaling pathway	57/897	216/7206	1.43198092499e-08
ko05322	Systemic lupus erythematosus	1/897	151/7206	6.18531037768e-08
ko04261	Adrenergic signaling in cardiomyocytes	53/897	205/7206	1.26223859505e-07
ko05031	Amphetamine addiction	30/897	91/7206	2.38346761628e-07
ko05203	Viral carcinogenesis	10/897	277/7206	3.61609061908e-07
ko04966	Collecting duct acid secretion	14/897	26/7206	4.41529187664e-07
ko03010	Ribosome	1/897	129/7206	1.13073345337e-06
ko04726	Serotonergic synapse	38/897	137/7206	1.16297400735e-06
ko04720	Long-term potentiation	30/897	99/7206	1.81110036636e-06
ko04744	Phototransduction	16/897	36/7206	1.87819843714e-06
ko05168	Herpes simplex infection	5/897	182/7206	6.05496310508e-06
ko04971	Gastric acid secretion	29/897	98/7206	6.55979358359e-06
ko04972	Pancreatic secretion	31/897	111/7206	8.47453193282e-06
ko03040	Spliceosome	3/897	145/7206	1.03982762461e-05
ko04120	Ubiquitin mediated proteolysis	3/897	138/7206	2.22265296834e-05
ko04742	Taste transduction	20/897	61/7206	2.66590585154e-05
ko04110	Cell cycle	4/897	145/7206	6.10518755342e-05
ko04925	Aldosterone synthesis and secretion	28/897	105/7206	6.79361907907e-05
ko03013	RNA transport	6/897	166/7206	0.000116116800439
ko04371	Apelin signaling pathway	40/897	177/7206	0.000122924219507
ko04350	TGF-beta signaling pathway	2/897	103/7206	0.000230707347501
ko04976	Bile secretion	22/897	80/7206	0.000232953333293
ko05161	Hepatitis B	7/897	173/7206	0.000249018140863
ko05169	Epstein-Barr virus infection	10/897	206/7206	0.000354251114889
ko04924	Renin secretion	23/897	86/7206	0.00037423161808
ko04014	Ras signaling pathway	55/897	279/7206	0.000405421717803
ko04745	Phototransduction - fly	13/897	38/7206	0.000427960608966
ko04730	Long-term depression	21/897	78/7206	0.000429000252521
ko04550	Signaling pathways regulating pluripotency of stem cells	7/897	165/7206	0.00046999583592
ko05030	Cocaine addiction	20/897	73/7206	0.000483257717961
ko05164	Influenza A	7/897	167/7206	0.000488876974522
ko04060	Cytokine-cytokine receptor interaction	9/897	191/7206	0.000493766315152
ko05166	HTLV-I infection	18/897	292/7206	0.000531435421197
ko05014	Amyotrophic lateral sclerosis (ALS)	20/897	74/7206	0.000566786407802
ko04514	Cell adhesion molecules (CAMs)	30/897	130/7206	0.000666018245012
ko05110	Vibrio cholerae infection	18/897	63/7206	0.000690205147663
ko04626	Plant-pathogen interaction	8/897	18/7206	0.000773595705586
ko00190	Oxidative phosphorylation	29/897	127/7206	0.000967354482384
ko05162	Measles	4/897	120/7206	0.00110287257163
ko05140	Leishmaniasis	1/897	75/7206	0.00114514111736
ko04070	Phosphatidylinositol signaling system	26/897	112/7206	0.00130622957679
ko01230	Biosynthesis of amino acids	21/897	85/7206	0.00150707568544
ko04710	Circadian rhythm	13/897	43/7206	0.00159620748812
ko04270	Vascular smooth muscle contraction	33/897	154/7206	0.00178673903627
ko04964	Proximal tubule bicarbonate reclamation	10/897	29/7206	0.00183056427303
ko05215	Prostate cancer	4/897	111/7206	0.00209684968693
ko04922	Glucagon signaling pathway	28/897	128/7206	0.00260239653721
ko04540	Gap junction	28/897	128/7206	0.00260239653721
ko03008	Ribosome biogenesis in eukaryotes	2/897	79/7206	0.00323447988594
ko00010	Glycolysis / Gluconeogenesis	18/897	74/7206	0.00407736842631
ko04260	Cardiac muscle contraction	22/897	98/7206	0.00500058970914
ko04750	Inflammatory mediator regulation of TRP channels	26/897	122/7206	0.00519949774049
ko05120	Epithelial cell signaling in Helicobacter pylori infection	21/897	92/7206	0.00595973206209
ko04621	NOD-like receptor signaling pathway	9/897	157/7206	0.00695702384986
ko00290	Valine, leucine and isoleucine biosynthesis	3/897	4/7206	0.00697665963473
ko05321	Inflammatory bowel disease (IBD)	1/897	56/7206	0.00787774341738
ko04657	IL-17 signaling pathway	3/897	87/7206	0.00789851794187
ko04210	Apoptosis	11/897	180/7206	0.0080490764138
ko00120	Primary bile acid biosynthesis	7/897	20/7206	0.00808832553733
ko05323	Rheumatoid arthritis	20/897	89/7206	0.0085746266361
ko04740	Olfactory transduction	18/897	80/7206	0.0100620225005
ko04010	MAPK signaling pathway	55/897	321/7206	0.0119445379541
ko04978	Mineral absorption	11/897	40/7206	0.0127496094328
ko05414	Dilated cardiomyopathy	23/897	112/7206	0.0135018251436
ko00260	Glycine, serine and threonine metabolism	12/897	48/7206	0.0142326761372
ko05217	Basal cell carcinoma	2/897	68/7206	0.0145653846821
ko04923	Regulation of lipolysis in adipocytes	17/897	77/7206	0.0147188904908
ko04915	Estrogen signaling pathway	26/897	131/7206	0.015288635854
ko05010	Alzheimer's disease	37/897	202/7206	0.0167342620072
ko04660	T cell receptor signaling pathway	7/897	124/7206	0.018796421263
ko00230	Purine metabolism	35/897	194/7206	0.0204415983174
ko01200	Carbon metabolism	25/897	128/7206	0.020682168606
ko00604	Glycosphingolipid biosynthesis - ganglio series	5/897	14/7206	0.0225362021466
ko04630	Jak-STAT signaling pathway	8/897	132/7206	0.0229528435154
ko00220	Arginine biosynthesis	7/897	24/7206	0.0231839236506
ko04015	Rap1 signaling pathway	47/897	278/7206	0.0258933298322
ko00950	Isoquinoline alkaloid biosynthesis	4/897	10/7206	0.0269873863444
ko04658	Th1 and Th2 cell differentiation	5/897	96/7206	0.0283442544993
ko04064	NF-kappa B signaling pathway	5/897	96/7206	0.0283442544993
ko00362	Benzoate degradation	3/897	6/7206	0.0287512307884
ko05220	Chronic myeloid leukemia	4/897	85/7206	0.0299026188313
ko04214	Apoptosis - fly	3/897	72/7206	0.0299168767105
ko00680	Methane metabolism	9/897	34/7206	0.0309135760272
ko00650	Butanoate metabolism	7/897	26/7206	0.0353700464765
ko04217	Necroptosis	13/897	178/7206	0.0376244125843
ko04974	Protein digestion and absorption	19/897	96/7206	0.0409674865703
ko04961	Endocrine and other factor-regulated calcium reabsorption	13/897	59/7206	0.0439119769681
ko04620	Toll-like receptor signaling pathway	6/897	100/7206	0.0472537705779
ko05200	Pathways in cancer	47/897	492/7206	0.0472831380951
ko04072	Phospholipase D signaling pathway	34/897	197/7206	0.0479248371648
ko05205	Proteoglycans in cancer	23/897	271/7206	0.0482459597096