ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 27/220 191/7206 1.63553394495e-11 ko04064 NF-kappa B signaling pathway 12/220 96/7206 3.15584161344e-05 ko04380 Osteoclast differentiation 13/220 134/7206 0.000211789734476 ko04668 TNF signaling pathway 12/220 120/7206 0.000279489934573 ko05164 Influenza A 14/220 167/7206 0.000555366668033 ko04621 NOD-like receptor signaling pathway 13/220 157/7206 0.000979349191562 ko04217 Necroptosis 14/220 178/7206 0.00104509898484 ko04657 IL-17 signaling pathway 9/220 87/7206 0.00126885628979 ko05131 Shigellosis 8/220 82/7206 0.0033962840618 ko04672 Intestinal immune network for IgA production 5/220 37/7206 0.00497953468212 ko04662 B cell receptor signaling pathway 8/220 88/7206 0.00524186527368 ko05323 Rheumatoid arthritis 8/220 89/7206 0.00561223961773 ko05167 Kaposi's sarcoma-associated herpesvirus infection 13/220 191/7206 0.00799701202529 ko00051 Fructose and mannose metabolism 5/220 42/7206 0.00859287307209 ko04650 Natural killer cell mediated cytotoxicity 8/220 97/7206 0.00933741451191 ko04130 SNARE interactions in vesicular transport 5/220 44/7206 0.0104447998194 ko05144 Malaria 5/220 45/7206 0.0114659485263 ko04660 T cell receptor signaling pathway 9/220 124/7206 0.0133297367458 ko05145 Toxoplasmosis 9/220 126/7206 0.0146849827273 ko05161 Hepatitis B 11/220 173/7206 0.0209942998575 ko04062 Chemokine signaling pathway 12/220 201/7206 0.0216669051766 ko05321 Inflammatory bowel disease (IBD) 5/220 56/7206 0.0274147263638 ko05132 Salmonella infection 7/220 98/7206 0.0298100170456 ko05152 Tuberculosis 11/220 187/7206 0.0305456555751 ko05100 Bacterial invasion of epithelial cells 7/220 99/7206 0.0312789071548 ko04620 Toll-like receptor signaling pathway 7/220 100/7206 0.0327957008543 ko04610 Complement and coagulation cascades 6/220 79/7206 0.0331254499722 ko04623 Cytosolic DNA-sensing pathway 4/220 41/7206 0.0354463638678 ko00140 Steroid hormone biosynthesis 4/220 41/7206 0.0354463638678 ko04723 Retrograde endocannabinoid signaling 1/220 175/7206 0.0453081897516 ko04390 Hippo signaling pathway 1/220 188/7206 0.0479621106165