ko pathway ratio_in_study ratio_in_pop p_value ko04060 Cytokine-cytokine receptor interaction 24/199 191/7206 3.50028289007e-10 ko04380 Osteoclast differentiation 19/199 134/7206 3.53232057621e-09 ko05150 Staphylococcus aureus infection 9/199 36/7206 3.84757366842e-07 ko05140 Leishmaniasis 11/199 75/7206 5.64031729365e-06 ko04610 Complement and coagulation cascades 11/199 79/7206 9.44840856126e-06 ko04650 Natural killer cell mediated cytotoxicity 12/199 97/7206 1.28440867994e-05 ko05321 Inflammatory bowel disease (IBD) 9/199 56/7206 1.91887215714e-05 ko04611 Platelet activation 15/199 163/7206 4.01697336755e-05 ko05152 Tuberculosis 16/199 187/7206 5.4156614037e-05 ko04640 Hematopoietic cell lineage 9/199 64/7206 5.76319639845e-05 ko04620 Toll-like receptor signaling pathway 11/199 100/7206 8.92550559187e-05 ko05162 Measles 12/199 120/7206 0.000108929173431 ko04666 Fc gamma R-mediated phagocytosis 12/199 122/7206 0.00012778823081 ko04064 NF-kappa B signaling pathway 10/199 96/7206 0.000293858188727 ko04621 NOD-like receptor signaling pathway 13/199 157/7206 0.00037911932489 ko05323 Rheumatoid arthritis 9/199 89/7206 0.000733847617869 ko04630 Jak-STAT signaling pathway 11/199 132/7206 0.00101091111489 ko05340 Primary immunodeficiency 5/199 30/7206 0.00123992652745 ko05144 Malaria 6/199 45/7206 0.0013646993481 ko04145 Phagosome 12/199 162/7206 0.00168689132408 ko05164 Influenza A 12/199 167/7206 0.00218205062189 ko05145 Toxoplasmosis 10/199 126/7206 0.00245316483888 ko04659 Th17 cell differentiation 9/199 106/7206 0.00253490402124 ko04662 B cell receptor signaling pathway 8/199 88/7206 0.00285073383615 ko00590 Arachidonic acid metabolism 6/199 52/7206 0.0029073071817 ko04810 Regulation of actin cytoskeleton 16/199 264/7206 0.00306042569715 ko04514 Cell adhesion molecules (CAMs) 10/199 130/7206 0.00308432664108 ko04672 Intestinal immune network for IgA production 5/199 37/7206 0.00324385750785 ko05168 Herpes simplex infection 12/199 182/7206 0.00442126487401 ko04664 Fc epsilon RI signaling pathway 7/199 77/7206 0.00517342445242 ko05202 Transcriptional misregulation in cancer 12/199 188/7206 0.0057197108503 ko04622 RIG-I-like receptor signaling pathway 6/199 62/7206 0.00699402228331 ko04660 T cell receptor signaling pathway 9/199 124/7206 0.00716542486963 ko05320 Autoimmune thyroid disease 4/199 29/7206 0.00780159679392 ko05133 Pertussis 7/199 87/7206 0.00998520168731 ko05310 Asthma 3/199 17/7206 0.0105998495972 ko04062 Chemokine signaling pathway 12/199 201/7206 0.0128856008208 ko04658 Th1 and Th2 cell differentiation 7/199 96/7206 0.0165697006056 ko04144 Endocytosis 17/199 342/7206 0.0167588997196 ko05132 Salmonella infection 7/199 98/7206 0.0183722335248 ko05130 Pathogenic Escherichia coli infection 6/199 77/7206 0.0192258967993 ko04612 Antigen processing and presentation 6/199 77/7206 0.0192258967993 ko05167 Kaposi's sarcoma-associated herpesvirus infection 11/199 191/7206 0.0209020893323 ko05020 Prion diseases 4/199 40/7206 0.0237454141485 ko04072 Phospholipase D signaling pathway 11/199 197/7206 0.0239941627217 ko05131 Shigellosis 6/199 82/7206 0.0253803185831 ko04137 Mitophagy - animal 6/199 82/7206 0.0253803185831 ko04623 Cytosolic DNA-sensing pathway 4/199 41/7206 0.0257609181511 ko05330 Allograft rejection 3/199 24/7206 0.027400345115 ko05161 Hepatitis B 10/199 173/7206 0.0286690901501 ko05169 Epstein-Barr virus infection 11/199 206/7206 0.0299957501724 ko04217 Necroptosis 10/199 178/7206 0.0317412566261 ko04933 AGE-RAGE signaling pathway in diabetic complications 8/199 135/7206 0.0329773312642 ko04670 Leukocyte transendothelial migration 9/199 151/7206 0.0375923977156 ko05166 HTLV-I infection 14/199 292/7206 0.0420751231533 ko00230 Purine metabolism 1/199 194/7206 0.045329823087